Results 101 to 110 of about 8,253 (208)
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT This case report highlights that Langerhans cell histiocytosis should be suspected in the differential diagnosis for children who exhibit failure to thrive, diabetes insipidus, and skin lesions. Early recognition and timely management are crucial for preventing irreversible hypothalamic–pituitary damage and improving outcomes.
Kidus Geabriel Yohannes +3 more
wiley +1 more source
The Role of Langerin⁺ CD8α⁺ Dendritic Cells in Tumour Immunotherapy [PDF]
, 2021 <p>The immune system has the potential to selectively target and eliminate tumours cells. However, the induction of an immunosuppressive environment by factors released by tumours cells, or by the tumour stroma, in combination with difficulties in differentiating between healthy and malignant cells, contributes to inefficient or disabled anti ...
openaire +1 more source
Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases
ChemistryEurope, Volume 4, Issue 2, February 2026.Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang +7 more
wiley +1 more source
Kovalente Aktivierung des C‐Typ Lektins DC‐SIGN
Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.Wir stellen die ersten kovalenten Aktivatoren eines C‐Typ‐Lektins vor. Mithilfe orthogonaler funktioneller Assays, NMR, MS/MS und computergestützter Modellierung untersuchen wir die Mechanismen eines funktionellen „Electrophile‐first“‐Screenings gegen DC‐SIGN.
Jonathan Lefèbre +9 more
wiley +1 more source
Langerhans cell histiocytosis in an adult patient
Vestnik Dermatologii i Venerologii, 2019 Aim: to present a clinical case of a rare dermatosis — Langerhans cell histiocytosis (LCH) in an adult patient.Materials and methods. A clinical and laboratory examination of a 64-year-old woman who had complained of rashes on the skin of the scalp, neck,
A. E. Karamova +5 more
doaj +1 more source
Targeting antigens to dendritic cell receptors for vaccine development [PDF]
, 2013 Dendritic cells (DCs) are highly specialized antigen presenting cells of the immune system which play a key role in regulating immune responses. Depending on the method of antigen delivery, DCs stimulate immune responses or induce tolerance.
Apostolopoulos, Vasso +3 more
core +2 more sources
Calcitonin gene-related peptide inhibits Langerhans cell-mediated HIV-1 transmission. [PDF]
, 2013 International audienceUpon its mucosal entry, human immunodeficiency virus type 1 (HIV-1) is internalized by Langerhans cells (LCs) in stratified epithelia and transferred locally to T cells.
Ahmed +37 more
core +4 more sources
Glycomimetic langerin ligands for Langerhans cell targeting
, 2017 Immune evasion represents an important hallmark of cancer progression. In this context, the induction of tumor-specific cytotoxic T cell immunity to overcome immunological tolerance has become a focal point of cancer immunotherapy. Langerhans cells (LCs) constitute a dendritic cell (DC) subset residing in the epidermis of the human skin. They have been
openaire +2 more sources
EBioMedicine, 2018 Langerhans cells (LCs) are antigen-presenting cells in the epidermis whose roles in antigen-specific immune regulation remain incompletely understood. Desmoglein 3 (Dsg3) is a keratinocyte cell-cell adhesion molecule critical for epidermal integrity and ...
Daniela Y. Kitashima +13 more
doaj +1 more source
Dendritic cells: Key players in human herpesvirus 8 infection and pathogenesis [PDF]
, 2014 Human herpesvirus 8 (HHV-8; Kaposi's sarcoma-associated herpesvirus) is an oncogenic gammaherpesvirus that primarily infects cells of the immune and vascular systems.
Akula +119 more
core +1 more source