Results 91 to 100 of about 5,193 (199)
Characterization of carbohydrate recognition by langerin, a C-type lectin of Langerhans cells [PDF]
Langerin is a type II transmembrane cell surface receptor found on Langerhans cells. The extracellular domain of langerin consists of a neck region containing a series of heptad repeats and a C-terminal C-type carbohydrate-recognition domain (CRD). A role for langerin in processing of glycoprotein antigens has been proposed, but until now there has ...
Nicola S, Stambach, Maureen E, Taylor
openaire +2 more sources
11‐year‐old girl presenting with blurred vision and progressive right arm weakness
Brain Pathology, EarlyView.
Trung Toan Tran +6 more
wiley +1 more source
ABSTRACT Rosai‐Dorfman disease is a rare non‐Langerhans cell histiocytic disorder. It is common in male children and young adults of African descent. It is classified into sporadic and familial types. The most common clinical presentation is massive bilateral cervical lymphadenopathy associated with constitutional symptoms. Histiocytic emperipolesis is
George Evele +2 more
wiley +1 more source
Langerin (CD207) represents a novel interferon-stimulated gene in Langerhans cells [PDF]
Interferons (IFNs) are “warning signal” cytokines released upon pathogen sensing. IFNs control the expression of interferon-stimulated genes (ISGs), which are often crucial to restrict viral infections and establish a cellular antiviral state.1,2 Langerin (CD207), a well-known surface receptor on Langerhans cells (LC), belongs to the C-type lectin ...
Ghizlane Maarifi +9 more
openaire +2 more sources
The opportunistic fungal pathogen Candida albicans frequently causes diseases such as oropharyngeal candidiasis (OPC) in immunocompromised individuals. Although it is well appreciated that the cytokine IL-17 is crucial for protective immunity against OPC,
Florian Sparber +8 more
doaj +1 more source
Langerin+CD8+ Dendritic Cells in the Splenic Marginal Zone: Not So Marginal After All
Dendritic cells (DC) fulfill an essential sentinel function within the immune system, acting at the interface of innate and adaptive immunity. The DC family, both in mouse and man, shows high functional heterogeneity in order to orchestrate immune ...
Ronald A. Backer +2 more
doaj +1 more source
ABSTRACT Introduction Histiocytic sarcoma (HS) is a rare neoplasm derived from non‐Langerhans histiocytic cells, exceptionally arising from B‐ALL. Methods We present the case of a child with high‐risk B‐ALL with PAX5 P80R mutation. Results Despite initial remission, a chemoresistant paravertebral mass was identified as HS.
Laetitia Largeaud +12 more
wiley +1 more source
Transfer of antigen between antigen-presenting cells (APCs) is potentially a physiologically relevant mechanism to spread antigen to cells with specialized stimulatory functions.
Troels R Petersen +4 more
doaj +1 more source
Alien Registration- Langerin, Ulrec (Rumford, Oxford County)
https://digitalmaine.com/alien_docs/12062/thumbnail ...
Langerin, Ulrec
core
Single Cell Analysis Reveals Dynamic Changes of Distinct Cell Populations in Human Nickel Allergy
We investigated cell types mediating the early and late inflammatory responses in human Ni2+‐allergy by scRNA‐Seq. Early responsiveness was mainly mediated by TLR4+TAGLN− endothelial cells indirectly activating TLR4−KRT16+ keratinocytes, and CCR7+DCN+ DCs. Late responsiveness was crucially driven by infiltration of KLF2+ central memory T cells and TLR4+
Marc Schmidt +7 more
wiley +1 more source

