Results 91 to 100 of about 5,672 (207)

Comparison of heparin and gp120 binding mode to Langerin.

, 2013
A) Overlay of sensorgram showing Langerin CRD interaction onto gp120YU2 functionalized surface in Ca2+ buffer. Langerin CRD concentration range is from 400 µM to 12,5 µM with 2 times serial dilution.
Romain R. Vivès (296307), Antoine Daina (170216), Franck Fieschi (296308), Eric Chabrol (296302), Michel Thepaut (296305), Eric Girard (266610), Emilie Vassal-Stermann (296304), Alessandra Nurisso (296303)   +7 more
core   +1 more source

Langerin+CD8+ Dendritic Cells in the Splenic Marginal Zone: Not So Marginal After All

Frontiers in Immunology, 2019
Dendritic cells (DC) fulfill an essential sentinel function within the immune system, acting at the interface of innate and adaptive immunity. The DC family, both in mouse and man, shows high functional heterogeneity in order to orchestrate immune ...
Ronald A. Backer, Nathalie Diener, Björn E. Clausen   +2 more
doaj   +1 more source

Identification of Epigenetic Regulator‐Associated Genes in Keloid Disease Through Integrated Bulk and Single‐Cell Transcriptomics With RT‐qPCR Validation

The FASEB Journal, Volume 40, Issue 16, 31 August 2026.
Step I: Screened HR/SMYD4 as key keloid epigenetic genes via bulk/scRNA‐seq and machine learning. Step II: Built a high‐performance nomogram (AUC = 0.988). Step III: Conducted multi‐omics analyses. Step IV: Experimentally verified their differential expression and pathogenic roles.
Yifei Wang, Shuqian Dou, Mingkun Dai, Guoxun Yang, Wenjun Liu   +4 more
wiley   +1 more source

Visualization and Characterization of Migratory Langerhans Cells in Murine Skin and Lymph Nodes by Antibodies Against Langerin/CD207

, 2003
Dendritic cells are professional antigen-presenting cells that initiate primary immunity. Migration from sites of antigen uptake to lymphoid organs is crucial for the generation of immune responses.
Kämmerer, Ulrike, Koch, Franz, Holzmann, Sandra, McLellan, Alexander D., Kämpgen, Eckhart, Kapp, Michaela, Stoitzner, Patrizia, Ivarsson, Lennart, Stössel, Hella, Douillard, Patrice, Saeland, Sem, Romani, Nikolaus   +11 more
core   +1 more source

11‐year‐old girl presenting with blurred vision and progressive right arm weakness

Brain Pathology, Volume 36, Issue 6, November 2026.
Trung Toan Tran, Thi My Hanh Luong, Bérengère Dadone‐Montaudié, Hong Nhung Ta, Thai Hoc Nguyen, Fanny Burel‐Vandenbos, Gia Du Pham   +6 more
wiley   +1 more source

A Novel Perfused Full‐Thickness Human Skin Microphysiological System for Modeling Injury, Regeneration, Tumor Pathophysiology, and Therapeutics Development

Advanced Healthcare Materials, Volume 15, Issue 31, 21 August 2026.
What if human skin could remain fully alive and functional outside the body for weeks? A New Alternative Method (NAM) based on a vascularized full‐thickness skin microphysiological system achieves precisely this, preserving native vasculature, resident immunity, and metabolic activity for up to three weeks, while faithfully recapitulating radiation ...
Yusuf Surucu, Hamid Malekzadeh, Alexa Rivera Del Rio Hernandez, Naresh Mahajan, Ethan Banks, Dayyan Ur Rahman, José A. Arellano, Katherine S. Yang, Alexey Altman, G.V. Naveen Kumar, Matthew L. Steinhauser, Jeffrey A. Gusenoff, J. Peter Rubin, Asim Ejaz   +13 more
wiley   +1 more source

Structural Studies of Langerin and Birbeck Granule: A Macromolecular Organization Model

, 2016
Dendritic cells, a sentinel immunity cell lineage, include different cell subsets that express various C-type lectins. For example, epidermal Langerhans cells express langerin, and some dermal dendritic cells express DC-SIGN.
Michel Thépaut (1788882), Richard Kahn (353779), Corinne Vivès (2384077), Sem Saeland (2384065), Colette Dezutter-Dambuyant (2384062), Bertrand Arnou (2384074), Christine Ebel (129858), Franck Fieschi (296308), Carine Monnier (2384071), Jenny Valladeau (2384068), Anne Imberty (75942), Alessandra Nurisso (296303)   +11 more
core   +1 more source

Exploiting the role of endogenous lymphoid-resident dendritic cells in the priming of NKT cells and CD8+ T cells to dendritic cell-based vaccines.

PLoS ONE, 2011
Transfer of antigen between antigen-presenting cells (APCs) is potentially a physiologically relevant mechanism to spread antigen to cells with specialized stimulatory functions.
Troels R Petersen, Dianne Sika-Paotonu, Deborah A Knight, Helen M A Simkins, Ian F Hermans   +4 more
doaj   +1 more source

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

The Journal of Pathology, Volume 269, Issue 4-5, Page 387-398, August 2026.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov, Juliana Faria Filipe, Sylvia Eidenhammer, German Ott, Iris Halbwedl, Karl Kashofer, Helmut Popper   +6 more
wiley   +1 more source

Unraveling cutaneous histiocytosis: insights into histology, pathogenesis, diagnosis, and treatment pitfalls

Frontiers in Medicine
Histiocytoses represent a group of diverse rare disorders characterized by the abnormal accumulation of cells derived from the mononuclear phagocyte system in various tissues and organs.
Lucian G. Scurtu, Lucian G. Scurtu, Francesca Scurtu, Francesca Scurtu, Olga Simionescu, Olga Simionescu   +5 more
doaj   +1 more source