Results 71 to 80 of about 5,672 (207)

Role of Serotonin in the Maintenance of Inflammatory State in Crohn’s Disease

Biomedicines, 2022
Crohn’s disease (CD) is a chronic intestinal inflammation considered to be a major entity of inflammatory bowel diseases (IBDs), affecting different segments of the whole gastrointestinal tract.
Simona Pergolizzi, Alessio Alesci, Antonio Centofanti, Marialuisa Aragona, Socrate Pallio, Ludovico Magaudda, Giuseppina Cutroneo, Eugenia Rita Lauriano   +7 more
doaj   +1 more source

Dual Lineages of Langerhans Cells Cooperate to Restore the Immune Barrier after Skin Injury

Advanced Science, Volume 13, Issue 59, 23 October 2026.
After skin injury, the epidermal immune barrier is rebuilt by two sources of Langerhans cells. Resident Langerhans cells first move into the wound during re‐epithelialization, guided by CXCR2 signaling. Later, recruited monocytes become long‐lived Langerhans cells.
Axel D. Schmitter‐Sánchez, Nicholas Basista, Sudhanshu Mishra, Hyeri Kim, Audrey Bench, Catherine Matte‐Martone, Min‐Soo Seo, Gun Woo Lee, Sangbum Park   +8 more
wiley   +1 more source

Editorial: Faux amis: Langerin-expressing DC in humans and mice [PDF]

Journal of Leukocyte Biology, 2015
Discussion on the identification of Langerin+ DC populations in humans.
openaire   +2 more sources

Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition [PDF]

, 2017
International audienceAt the surface of dendritic cells, C-type lectin receptors (CLRs) allow the recognition of carbohydrate-based PAMPS or DAMPS (pathogen- or danger-associated molecular patterns, respectively) and promote immune response regulation ...
Thépaut, Michel, Eric Chabrol, Varga, Norbert, Vanessa Porkolab, Sutkevičiu Tė, Ieva, Ordanini, Stefania, Franck Fieschi, Sutkeviciute, Ieva, Anna Bernardi, Michel Thépaut, Eric Girard, Fieschi, Franck, Girard, Eric, García-Jiménez, Maria José, Bernardi, Anna, Nieto, Pedro, Nieto, Pedro M., Pedro M. Nieto, Nieto, Pedro M, Ieva Sutkevičiu̅tė, Maria José García-Jiménez, Norbert Varga, Chabrol, Eric, Stefania Ordanini, Porkolab, Vanessa   +24 more
core   +1 more source

BRAF V600E and Pten deletion in mice produces a histiocytic disorder with features of Langerhans cell histiocytosis.

PLoS ONE, 2019
Langerhans cell histiocytosis (LCH) is characterized by the accumulation of Langerin (CD207)-expressing histiocytes. Mutational activation of mitogen-activated protein kinase pathway genes, in particular BRAF, drives most cases. To test whether activated
David S Nelson, Ryan L Marano, Yechaan Joo, Sara Y Tian, Bhumi Patel, Daniel H Kaplan, Mark J Shlomchik, Kristen Stevenson, Roderick T Bronson, Barrett J Rollins   +9 more
doaj   +1 more source

Detection of intraepithelial and stromal Langerin and CCR5 positive cells in the human endometrium: potential targets for HIV infection. [PDF]

PLoS ONE, 2011
Both the upper (endocervix and uterus) and lower (ectocervix and vagina) female genital tract mucosa are considered to be target sites for sexual transmission of HIV. There are a few reports on the T cell and antigen-presenting cell distribution in human
Tove Kaldensjö, Pernilla Petersson, Anna Tolf, Gareth Morgan, Kristina Broliden, Taha Hirbod   +5 more
doaj   +1 more source

Chronic Pruritic Papular Eruption in an Elderly Man

JEADV Clinical Practice, EarlyView.
Filipe Monteiro, Inês Tribolet‐Abreu, Gustavo Almeida‐Silva, Inês Amaral, Ivânia Soares, Sónia Fernandes, Joana Antunes   +6 more
wiley   +1 more source

An Overlap of Erdheim–Chester Disease and Rosai–Dorfman Disease With Isolated Bone Lesions Presenting a Diagnostic Challenge: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Some of the rarest diseases with cell accumulation in different organs are histiocytoses. Since these diagnoses are uncommon, other differential diagnoses must be excluded. We report a case of a 42‐year‐old man with episodes of knee pain and fever.
Maris Tulk, Reet Kuuse, Maksim Zagura, Hazem M. M. Ali, Liis Vahesaar   +4 more
wiley   +1 more source

Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function.

, 2005
Langerin is a C-type lectin expressed by a subset of dendritic leukocytes, the Langerhans cells (LC). Langerin is a cell surface receptor that induces the formation of an LC-specific organelle, the Birbeck granule (BG). We generated a langerin(-/-) mouse
Prina, Eric, Coste, Isabelle, Bordat, Yann, Aït-Yahia, Smina, Gresser, Olivia, Renno, Toufic, Badell, Edgar, Malissen, Bernard, Douillard, Patrice, Clair-Moninot, Valérie, Lang, Thierry, Pooley, Joanne L, Winter, Nathalie, Shortman, Ken, Milon, Geneviève, Lebecque, Serge, Stössel, Hella, Romani, Nikolaus, Saeland, Sem, Kissenpfennig, Adrien   +19 more
core   +1 more source

A frontal lobe mass in a 6‐year‐old girl

Brain Pathology, EarlyView.
Francesca S. Vacca, Aaron Mochizuki, Smruti K. Patel, Blaise Jones, Somak Roy, Kirti Gupta   +5 more
wiley   +1 more source