Results 71 to 80 of about 5,193 (199)

Perineurioma‐like EMA‐positive calvarial neoplasms: clinicopathological study of eight cases

Histopathology, EarlyView.
Perineurioma‐like, EMA‐positive calvarial neoplasms (PLECN) are a rare group of intraosseous spindle cell tumours that demonstrate overlapping morphologic features of perineurioma and fibroblastic meningioma. These lesions tend to behave indolently but show a propensity for progressive growth.
Raheel Rizwan, Yingting Mok, Josephine K Dermawan, Alexandra Isaacson, Veronica Ulici, Scott E Kilpatrick, John D Reith, Gabrielle Yeaney, Hakan Ilaslan, Karen J Fritchie   +9 more
wiley   +1 more source

Coexpression of CD1a, langerin and Birbeck's granules in Langerhans cell histiocytoses (LCH) in children: ultrastructural and immunocytochemical studies.

Folia Histochemica et Cytobiologica, 2007
Langerhans cell histiocytoses (LCH) represent rare diseases of unclear etiology and pathogenesis. Most of the cases include children, 1 to 15 years of age, and various organs are involved (bones, skin, liver, lymph nodes, bone marrow and other).
Marzena Podhorska-Okołów, Michał Jeleń, Jadwiga Wecławek, Malgorzata Dumańska, Barbara Dolilńska-Krajewska, Piotr Dziegiel, Ewa Jagoda, Magdalena Fic, Maciej Zabel   +8 more
doaj   +1 more source

Interaction properties of Langerin to different glycosaminoglycans.

, 2013
(A-C) Structure of glycosaminoglycan disaccharides. Disaccharide units for heparin/HS (A), CS/DS (B) or KS (C). R = COCH3 or SO3H; X = H or SO3. The star indicates presence of glucuronic or iduronic acid C-5 epimers.
Romain R. Vivès (296307), Antoine Daina (170216), Franck Fieschi (296308), Eric Chabrol (296302), Michel Thepaut (296305), Eric Girard (266610), Emilie Vassal-Stermann (296304), Alessandra Nurisso (296303)   +7 more
core   +1 more source

Epidemiology of Canine Cutaneous Histiocytoma: Insights From Age and Topographic Clustering

Veterinary Dermatology, EarlyView.
Background: Canine cutaneous histiocytoma (CCH) is a benign Langerhans‐cell tumour that often regresses spontaneously via inflammation. Objectives: To estimate incidence and characterise age and breed–anatomical‐site patterns using two complementary clustering analyses.
C. De Moura, K. Pinello, J. Catarino, J. Niza‐Ribeiro, J. Santos, P. Faísca   +5 more
wiley   +1 more source

Morphological Alterations and Increased S100B Expression in Epidermal Langerhans Cells Detected in Skin from Patients with Progressive Vitiligo

Life, 2021
The role of Langerhans cells (LCs) in vitiligo pathogenesis remains unclear, with published studies reporting contradictory results regarding the quantity of LCs and no data on the features of LCs in vitiligo.
Fei Yang, Lingli Yang, Lanting Teng, Huimin Zhang, Ichiro Katayama   +4 more
doaj   +1 more source

Carbohydrate-Dependent Binding of Langerin to SodC, a Cell Wall Glycoprotein of Mycobacterium leprae [PDF]

, 2014
Langerhans cells participate in the immune response in leprosy by their ability to activate T cells that recognize the pathogen, Mycobacterium leprae, in a langerin-dependent manner.
Robert L. Modlin, Heaslip, Darragh, Mark C. Udey, Belisle, John T, John T. Belisle, Udey, Mark C, Brennan, Patrick J, Patrick J. Brennan, Kim, Hee Jin, Darragh Heaslip, Modlin, Robert L, Hee Jin Kim   +11 more
core   +1 more source

Immunohistochemical expression of Langerin in Langerhans cell histiocytosis and non-Langerhans cell histiocytic disorders

, 2008
Langerin is a type II transmembrane C-type lectin associated with the formation of Birbeck granules in Langerhans cells. Langerin is a highly selective marker for Langerhans cells and the lesional cells of Langerhans cell histiocytosis. Although Langerin
Chu, Peiguo G., Weiss, Lawrence M., Lau, Sean K.   +2 more
core   +1 more source

BRAF V600E and Pten deletion in mice produces a histiocytic disorder with features of Langerhans cell histiocytosis.

PLoS ONE, 2019
Langerhans cell histiocytosis (LCH) is characterized by the accumulation of Langerin (CD207)-expressing histiocytes. Mutational activation of mitogen-activated protein kinase pathway genes, in particular BRAF, drives most cases. To test whether activated
David S Nelson, Ryan L Marano, Yechaan Joo, Sara Y Tian, Bhumi Patel, Daniel H Kaplan, Mark J Shlomchik, Kristen Stevenson, Roderick T Bronson, Barrett J Rollins   +9 more
doaj   +1 more source

Role of Serotonin in the Maintenance of Inflammatory State in Crohn’s Disease

Biomedicines, 2022
Crohn’s disease (CD) is a chronic intestinal inflammation considered to be a major entity of inflammatory bowel diseases (IBDs), affecting different segments of the whole gastrointestinal tract.
Simona Pergolizzi, Alessio Alesci, Antonio Centofanti, Marialuisa Aragona, Socrate Pallio, Ludovico Magaudda, Giuseppina Cutroneo, Eugenia Rita Lauriano   +7 more
doaj   +1 more source

Metabolic Tagging of Tumour Extracellular Vesicles for Targeted Modulation of Dendritic Cells

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) have emerged as a promising alternative to cell‐based therapies due to their benign safety profiles and favourable pharmacokinetic properties. Tumour EVs, in particular, have shown promise to function as a therapeutic cancer vaccine for various cancer types.
Rimsha Bhatta, Wenhao Xu, Ruike Dai, Yusheng Liu, Jiadiao Zhou, Yixin Xue, Hua Wang   +6 more
wiley   +1 more source