Results 71 to 80 of about 8,253 (208)

Editorial: Faux amis: Langerin-expressing DC in humans and mice [PDF]

Journal of Leukocyte Biology, 2015
Discussion on the identification of Langerin+ DC populations in humans.
openaire   +2 more sources

Regulating the adaptive immune response to respiratory virus infection [PDF]

, 2012
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Braciale, Thomas J., Kim, Taeg S., Sun, Jie   +2 more
core   +1 more source

Engagement of a Neighboring Lys Residue by a Salicylaldehyde‐Modified Glycomimetic Ligand Enables Potent and Selective Binding to DC‐SIGN Over L‐SIGN

ChemistryEurope, Volume 4, Issue 5, May 2026.
Mannose derivatives connected to the aminophilic salicylaldehyde tag show high binding affinity for C‐type lectin DC‐SIGN, favored by an imine bond with a protein's Lys residue in the ligand binding site. This reversible‐covalent binding interaction enables ligand selectivity for DC‐SIGN over the closely related L‐SIGN.
Sara Pollastri, Clara Delaunay, Giulia Antonini, Carine Froment, Michel Thépaut, Davide Pasquali, Sarah Mazzotta, Laura Belvisi, Julien Marcoux, Franck Fieschi, Alberto Dal Corso, Anna Bernardi   +11 more
wiley   +1 more source

Functional Redundancy of Langerhans Cells and Langerin+ Dermal Dendritic Cells in Contact Hypersensitivity [PDF]

Journal of Investigative Dermatology, 2010
The relative roles of Langerhans cells (LC), dermal dendritic cells (DC), and, in particular, the recently discovered Langerin(+) dermal DC subset in the induction and control of contact hypersensitivity (CHS) responses remain controversial. Using an inducible mouse model, in which LC and other Langerin(+) DC can be depleted by injection of diphtheria ...
Noordegraaf, Madelon, Flacher, Vincent, Stoitzner, Patrizia, Clausen, Björn   +3 more
openaire   +3 more sources

Molecular Interactions of β-(1→3)-Glucans with Their Receptors

Molecules, 2015
β-(1→3)-Glucans can be found as structural polysaccharides in cereals, in algae or as exo-polysaccharides secreted on the surfaces of mushrooms or fungi.
Laurent Legentil, Franck Paris, Caroline Ballet, Sophie Trouvelot, Xavier Daire, Vaclav Vetvicka, Vincent Ferrières   +6 more
doaj   +1 more source

Human anogenital monocyte-derived dendritic cells and langerin+cDC2 are major HIV target cells

Nature Communications, 2021
Epithelial tissue mononuclear phagocytes (MNP) can transmit HIV to CD4 T cells, but less is known about sub-epithelial cells. Here, the authors describe MNPs in human anogenital and colorectal tissues and find that CD14+CD1c+ monocyte-derived dendritic ...
Jake W. Rhodes, Rachel A. Botting, Kirstie M. Bertram, Erica E. Vine, Hafsa Rana, Heeva Baharlou, Peter Vegh, Thomas R. O’Neil, Anneliese S. Ashhurst, James Fletcher, Grant P. Parnell, J. Dinny Graham, Najla Nasr, Jake J. K. Lim, Laith Barnouti, Peter Haertsch, Martijn P. Gosselink, Angelina Di Re, Faizur Reza, Grahame Ctercteko, Gregory J. Jenkins, Andrew J. Brooks, Ellis Patrick, Scott N. Byrne, Eric Hunter, Muzlifah A. Haniffa, Anthony L. Cunningham, Andrew N. Harman   +27 more
doaj   +1 more source

Novel Approaches for Investigating Host Responses to HIV Infection in Ex Vivo Human Genital Tissues

American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Understanding local immune responses and the structural integrity of the genital mucosal barrier is essential for advancing knowledge of both susceptibility to sexual HIV transmission and the pathogenesis of chronic HIV infection. This review highlights innovative methodologies for investigating host responses to HIV infection using ex vivo ...
Mathias Franzén Boger, Vilde Kaldhusdal, Kristina Broliden   +2 more
wiley   +1 more source

Clinicopathological Features, Treatment Response, and Outcome of Rosai‐Dorfman Disease in Two Children

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Rosai‐Dorfman disease is a rare non‐Langerhans cell histiocytic disorder. It is common in male children and young adults of African descent. It is classified into sporadic and familial types. The most common clinical presentation is massive bilateral cervical lymphadenopathy associated with constitutional symptoms. Histiocytic emperipolesis is
George Evele, Kouya Francine, Richard Bardin   +2 more
wiley   +1 more source

Calcium‐Independent Activation of an Allosteric Network in Langerin by Heparin Oligosaccharides [PDF]

ChemBioChem, 2017
AbstractThe C‐type lectin receptor Langerin is a glycan‐binding protein that serves as an uptake receptor on Langerhans cells and is essential for the formation of Birbeck granules. Whereas most Langerin ligands are recognized by a canonical Ca2+‐dependent binding site, heparins have been proposed to make additional contacts to a secondary, Ca2 ...
Jonas Hanske, Robert Wawrzinek, Andreas Geissner, Eike‐Christian Wamhoff, Katrin Sellrie, Henrik Schmidt, Peter H. Seeberger, Christoph Rademacher   +7 more
openaire   +3 more sources

Morphological Alterations and Increased S100B Expression in Epidermal Langerhans Cells Detected in Skin from Patients with Progressive Vitiligo

Life, 2021
The role of Langerhans cells (LCs) in vitiligo pathogenesis remains unclear, with published studies reporting contradictory results regarding the quantity of LCs and no data on the features of LCs in vitiligo.
Fei Yang, Lingli Yang, Lanting Teng, Huimin Zhang, Ichiro Katayama   +4 more
doaj   +1 more source