Results 51 to 60 of about 8,253 (208)

Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization. [PDF]

PLoS ONE, 2011
Dendritic cells (DCs) subsets differ in precursor cell of origin, functional properties, requirements for growth factors, and dependence on transcription factors.
Brian T Edelson, Tara R Bradstreet, Wumesh KC, Kai Hildner, Jeremy W Herzog, Julia Sim, John H Russell, Theresa L Murphy, Emil R Unanue, Kenneth M Murphy   +9 more
doaj   +1 more source

Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo

, 2012
After activation, Langerhans cells (LC), a distinct subpopulation of epidermis-resident dendritic cells, migrate from skin to lymph nodes where they regulate the magnitude and quality of immune responses initiated by epicutaneously applied antigens ...
Feng, X., Gaiser, M., Germain, R., Igyarto, B., Kaplan, D., Lämmermann, T., Tessarollo, L., Udey, a.   +7 more
core   +1 more source

Hepatic Langerhans cell histiocytosis: Report of a rare case

Human Pathology Reports, 2023
Langerhans cell histiocytosis (LCH) is a rare neoplastic disease characterized by abnormal proliferation of Langerhans cells infiltrating various organs, resulting in organ dysfunction.
Renling Yao, Jun Chen, Jie Li
doaj   +1 more source

HIV Types, Groups, Subtypes and Recombinant Forms: Errors in Replication, Selection Pressure and Quasispecies [PDF]

, 2012
HIV-1 is a chimpanzee virus which was transmitted to humans by several zoonotic events resulting in infection with HIV-1 groups M P, and in parallel transmission events from sooty mangabey monkey viruses leading to infections with HIV-2 groups A H.
Alvarez M, Batmanian J, Bocharov G, Brennan CA, Burgard M, Buzon MJ, Dahl V, Dai L, Domingo E, Duarte EA, Etienne L, Fang G, Fultz PN, Gunthard HF, Henriet S, Iordanskiy S, Josef Eberle, Julg B, Kijak GH, Korber B, Law M, Lemey P, Lorenzo-Redondo R, Lutz G. Gürtler, Motomura K, Neel C, Onafuwa-Nuga A, Pathak VK, Pathak VK, Rachinger A, Sauter D, Shimizu N, Simon-Loriere E, Smith DM, Sterjovski J, Swenson LC, Tienen C, Troyer JL, Van der Kuyl AC, Van der Vlist M, Zhu T   +40 more
core   +1 more source

Ontogeny of Langerin/CD207 Expression in the Epidermis of Mice [PDF]

Journal of Investigative Dermatology, 2004
C-type lectin receptors help Langerhans cells (LC) to take up and process pathogens. Langerin/CD207 is a mannose-binding C-type lectin that is specifically expressed by LC. It is involved in antigen uptake in an as yet poorly defined way, and it is a major molecular constituent of Birbeck granules.
Tripp, Christoph H., Chang-Rodriguez, Souyet, Stoitzner, Patrizia, Holzmann, Sandra, Stössel, Hella, Douillard, Patrice, Saeland, Sem, Koch, Franz, Elbe-Bürger, Adelheid, Romani, Nikolaus   +9 more
openaire   +2 more sources

The Essential Role of anxA2 in Langerhans Cell Birbeck Granules Formation

Cells, 2020
Langerhans cells (LC) are the resident antigen presenting cells of the mucosal epithelium and play an essential role in initiating immune responses.
Shantae M. Thornton, Varsha D. Samararatne, Joseph G. Skeate, Christopher Buser, Kim P. Lühen, Julia R. Taylor, Diane M. Da Silva, W. Martin Kast   +7 more
doaj   +1 more source

Activin A induces Langerhans cell differentiation in vitro and in human skin explants. [PDF]

PLoS ONE, 2008
Langerhans cells (LC) represent a well characterized subset of dendritic cells located in the epidermis of skin and mucosae. In vivo, they originate from resident and blood-borne precursors in the presence of keratinocyte-derived TGFbeta.
Tiziana Musso, Sara Scutera, William Vermi, Roberta Daniele, Michele Fornaro, Carlotta Castagnoli, Daniela Alotto, Maria Ravanini, Irene Cambieri, Laura Salogni, Angela Rita Elia, Mirella Giovarelli, Fabio Facchetti, Giampiero Girolomoni, Silvano Sozzani   +14 more
doaj   +1 more source

Impaired Differentiation of Langerhans Cells in the Murine Oral Epithelium Adjacent to Titanium Dental Implants

Frontiers in Immunology, 2018
Peri-implantitis is a destructive inflammatory process affecting tissues surrounding dental implants and it is considered a new global health concern.
Oded Heyman, Noam Koren, Gabriel Mizraji, Gabriel Mizraji, Tal Capucha, Sharon Wald, Maria Nassar, Yaara Tabib, Lior Shapira, Avi-Hai Hovav, Asaf Wilensky   +10 more
doaj   +1 more source

Identification and Characterization of Endogenous Langerin Ligands in Murine Extracellular Matrix [PDF]

Journal of Investigative Dermatology, 2006
Langerin is a C-type lectin that is expressed by Langerhans cells (LC) and related immune cells, and believed to play an important role in antigen recognition and uptake. To determine if Langerin has endogenous ligands, we generated S protein binding, bacterial recombinant, mouse soluble Langerin, and utilized it as a probe.
Tada, Yayoi, Riedl, Elisabeth, Lowenthal, Mark S., Liotta, Lance A., Briner, David M., Crouch, Erika C., Udey, Mark C.   +6 more
openaire   +2 more sources

Characterization of Langerin-Expressing Dendritic Cell Subsets in the Normal Cornea [PDF]

Investigative Opthalmology & Visual Science, 2011
In addition to Langerhans cells (LCs), other dendritic cells (CD11c(+)) have recently been shown to express Langerin (c-type lectin). In skin, (non-LC) Langerin+ dendritic cells initiate adaptive immunity. However, whether such dendritic cells (DC) reside in the cornea, an immune-privileged tissue, is unknown.Normal C57BL/6 corneas were harvested for ...
Hattori, Takaaki, Chauhan, Sunil, Lee, Hyunsoo, Ueno, Hiroki, Dana, Reza, Kaplan, Daniel H., Saban, Daniel R.   +6 more
openaire   +3 more sources