Results 61 to 70 of about 8,253 (208)

Studies of human dendritic cells in the skin after antigen exposure [PDF]

, 2012
Dendritic cells (DCs) act at the interface of innate and adaptive immunity. They are capable of inducing strong effector immune responses to invading pathogens, but also exert important functions in the maintenance of tolerance.
Bond, Emily
core   +1 more source

Fluorinated Glycan Frameshifts: Automated Synthesis Expedites the Study of Glycan‐Protein Interactions by 19F‐BioNMR

Angewandte Chemie, Volume 138, Issue 12, 16 March 2026.
Given the prominence of 19F‐bioNMR in structural research, fluorinated glycans hold enormous potential in glycomimetic frameshift design. However, challenges associated with the stereocontrolled synthesis of these disruptive actors continue to frustrate advances. To address this, the automated synthesis of selectively C‐2 fluorinated glycans related to
James Suri, Christina Jordan, Charlotte S. Teschers, Kristina Schlangen, Simon H. Rüdisser, Alvar D. Gossert, Ryan Gilmour   +6 more
wiley   +2 more sources

A Rare Case of Cutaneous Crystal‐Storing Histiocytosis With Kappa Light Chain Restriction and Unusual BCL6 Expression

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Crystal‐storing histiocytosis (CSH) is a rare histopathologic phenomenon characterized by the accumulation of crystalline material within histiocytes, most often associated with lymphoplasmacytic or plasma cell neoplasms. Cutaneous involvement is uncommon and may present diagnostic challenges.
Liangli Wang, Jonathan L. Curry, Julia Dai, Daniel H. Wang, Paolo Strati, Melody R. Becnel, Leomar Y. Ballester, Carlos A. Torres‐Cabala, Phyu P. Aung   +8 more
wiley   +1 more source

Coexpression of CD1a, langerin and Birbeck's granules in Langerhans cell histiocytoses (LCH) in children: ultrastructural and immunocytochemical studies.

Folia Histochemica et Cytobiologica, 2007
Langerhans cell histiocytoses (LCH) represent rare diseases of unclear etiology and pathogenesis. Most of the cases include children, 1 to 15 years of age, and various organs are involved (bones, skin, liver, lymph nodes, bone marrow and other).
Marzena Podhorska-Okołów, Michał Jeleń, Jadwiga Wecławek, Malgorzata Dumańska, Barbara Dolilńska-Krajewska, Piotr Dziegiel, Ewa Jagoda, Magdalena Fic, Maciej Zabel   +8 more
doaj   +1 more source

An unusual case of intertrigo in an adult caused by purely cutaneous Langerhans cell histiocytosis [PDF]

, 2016
We report a case of persistent intertrigo in an adult, eventually diagnosed as cutaneous Langerhans cell histiocytosis (LCH). It is known that LCH has a predilection for intertriginous areas, however purely cutaneous disease as in our case, is uncommon ...
Baldacchino, Godfrey, Betts, Alexandra, Boffa, Michael J., Gatt, Alex   +3 more
core  

Tumor-infiltrating macrophages and dendritic cells in human colorectal cancer: relation to local regulatory T cells, systemic T-cell response against tumor-associated antigens and survival [PDF]

, 2007
Introduction Although systemic T-cell responses against tumor antigens and tumor infiltration by T cells have been investigated in colorectal cancer (CRC), the initiation of spontaneous immune responses in situ is not well understood.
Dirk Nagorsen, Sabine Voigt, Erika Berg, Harald Stein, Eckhard Thiel, Christoph Loddenkemper, KM Ropponen, Y Naito, A Oberg, AC Diederichsen, Y Funada, T Blankenstein, C Allen, D Sickert, Y Nakayama, AR Dadabayev, NA Zeid, M Furihata, ID Nagtegaal, AA Khorana, C Lackner, C Loddenkemper, RM Steinman, FO Nestle, MC Panelli, J Banchereau, T Schwaab, P Demetter   +27 more
core   +2 more sources

Epidemiology of Canine Cutaneous Histiocytoma: Insights From Age and Topographic Clustering

Veterinary Dermatology, EarlyView.
Background: Canine cutaneous histiocytoma (CCH) is a benign Langerhans‐cell tumour that often regresses spontaneously via inflammation. Objectives: To estimate incidence and characterise age and breed–anatomical‐site patterns using two complementary clustering analyses.
C. De Moura, K. Pinello, J. Catarino, J. Niza‐Ribeiro, J. Santos, P. Faísca   +5 more
wiley   +1 more source

Langerin (CD207) represents a novel interferon-stimulated gene in Langerhans cells [PDF]

Cellular & Molecular Immunology, 2019
Interferons (IFNs) are “warning signal” cytokines released upon pathogen sensing. IFNs control the expression of interferon-stimulated genes (ISGs), which are often crucial to restrict viral infections and establish a cellular antiviral state.1,2 Langerin (CD207), a well-known surface receptor on Langerhans cells (LC), belongs to the C-type lectin ...
Ghizlane Maarifi, Magdalena A. Czubala, Justine Lagisquet, Matthew O. Ivory, Kyra Fuchs, Laure Papin, James C. Birchall, Sébastien Nisole, Vincent Piguet, Fabien P. Blanchet   +9 more
openaire   +2 more sources

Filaggrin-null mutations are associated with increased maturation markers on Langerhans cells [PDF]

, 2016
Background Mutations in the gene encoding filaggrin (FLG), an epidermal structural protein, are the strongest risk factor identified for the development of atopic dermatitis (AD).
Andrew J. Muinonen-Martin, Angelova-Fischer, Banchereau, Bashir, Berth-Jones, Brown, Chu, Claire S. Leitch, Correale, Cunjing Yu, Dahl, Di Gennaro, Eenass Natafji, Elias, Gibbs, Gibbs, Gibbs, Gilmour, Gilmour, Harriott-Smith, Jürgen Schwarze, Kammeyer, Kammeyer, Kaneko, Kezic, Laihia, Leung, Linda E. Campbell, Loffler, McAleer, McGrath, Meunier, Nayani Madarasingha, Norval, Pasanen, Pasanen, Paul M. Fitch, Peltonen, Pinnagoda, Prechtel, Richard B. Weller, Roland Chu, Romani, Romani, Ross, Sadhu, Sarah E.M. Howie, Seneschal, Sergeant, Sharizan Abdul-Ghaffar, Shibaki, Smith, W.H. Irwin McLean, Williams, Yoshida, Zoë C. Venables   +55 more
core   +4 more sources

Efficacy, safety, and relapse outcomes of MAPK inhibitors in pediatric Langerhans cell histiocytosis: A real‐world study

International Journal of Cancer, Volume 158, Issue 10, Page 2674-2683, 15 May 2026.
What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang, Jing‐jing Sun, Zhi Wan, Xiao‐yu Jing, Xia Guo, Ju Gao   +5 more
wiley   +1 more source