Results 41 to 50 of about 5,193 (199)

Effect of ultrasound treatment of the skin on activation of Langerhans cells and antibody production in rodents

Journal of Advanced Pharmaceutical Technology & Research, 2023
In this study, we investigated whether stimulating the skin with ultrasound (US) could activate Langerhans cells (LCs) – antigen-presenting cells in the epidermis and stimulate antibody production following the subcutaneous and intradermal injection of ...
Satoko Enjo, Yutaro Hazama, Soichiro Kimura, Yasunori Morimoto, Hideo Ueda   +4 more
doaj   +1 more source

Computational and experimental prediction of human C-type lectin receptor druggability

Frontiers in Immunology, 2014
Mammalian C-type lectin receptors are involved in many aspects of immune cell regulation such as pathogen recognition, clearance of apoptotic bodies and lymphocyte homing.
Jonas eAretz, Jonas eAretz, Eike-Christian eWamhoff, Eike-Christian eWamhoff, Jonas eHanske, Jonas eHanske, Dario eHeymann, Christoph eRademacher, Christoph eRademacher   +8 more
doaj   +1 more source

Pyodermatitis-Pyostomatitis Vegetans: The Role of Langerin Deficiency in Disease Pathogenesis. [PDF]

J Clin Med
Background/Objectives: Pyodermatitis–pyostomatitis vegetans (PPV) is a rare, chronic inflammatory mucocutaneous disorder. However, the etiology of PPV remains controversial. Methods: A review of online PPV case studies from PubMed, Wanfang database, Web of Science, and books has been performed.
Pan D, Wang J, Cai L, Huang M, Han Q, Zheng Z, Zeng X, Chen Q, Ai R, Zhou Y.   +9 more
europepmc   +3 more sources

Alteration of the Langerin Oligomerization State Affects Birbeck Granule Formation [PDF]

Biophysical Journal, 2015
Langerin, a trimeric C-type lectin specifically expressed in Langerhans cells, has been reported to be a pathogen receptor through the recognition of glycan motifs by its three carbohydrate recognition domains (CRD). In the context of HIV-1 (human immunodeficiency virus-1) transmission, Langerhans cells of genital mucosa play a protective role by ...
Chabrol, Eric, Thépaut, Michel, Dezutter-Dambuyant, Colette, Vivès, Corinne, Marcoux, Julien, Kahn, Richard, Valladeau-Guilemond, Jenny, Vachette, Patrice, Durand, Dominique, Fieschi, Franck   +9 more
openaire   +3 more sources

Role of langerin+ cells in skin pathologies

, 2021
Langerhans cells (LCs) are epidermal immune cells that express C-type lectin receptor langerin along with a subset of dermal dendritic cells. Langerin+ cells play a pivotal role in skin immunity. Previous research has suggested that LC may be involved in
Rajesh, Aarthi
core   +1 more source

Langerin+ CD8α+ Dendritic Cells Drive Early CD8+ T Cell Activation and IL-12 Production During Systemic Bacterial Infection

Frontiers in Immunology, 2018
Bloodstream infections induce considerable morbidity, high mortality, and represent a significant burden of cost in health care; however, our understanding of the immune response to bacteremia is incomplete.
Kelly A. Prendergast, Kelly A. Prendergast, Naomi J. Daniels, Troels R. Petersen, Ian F. Hermans, Ian F. Hermans, Ian F. Hermans, Joanna R. Kirman, Joanna R. Kirman   +8 more
doaj   +1 more source

Syndecan 4 Upregulation on Activated Langerhans Cells Counteracts Langerin Restriction to Facilitate Hepatitis C Virus Transmission

Frontiers in Immunology, 2020
Sexually transmitted Hepatitis C virus (HCV) infections and high reinfections are a major concern amongst men who have sex with men (MSM) living with HIV-1 and HIV-negative MSM.
Bernadien M. Nijmeijer, Julia Eder, Catharina J. M. Langedijk, Tanja M. Kaptein, Sofie Meeussen, Pascale Zimmermann, Pascale Zimmermann, Carla M. S. Ribeiro, Teunis B. H. Geijtenbeek   +8 more
doaj   +1 more source

CD1a and langerin: acting as more than Langerhans cell markers [PDF]

Journal of Clinical Investigation, 2004
Langerhans cells (LCs) represent a unique DC subset populating the outermost body surface, i.e., the epidermis. Although CD1a and langerin (CD207) are used as specific markers to distinguish LCs from other DC subsets, their immunological functions have remained mostly unknown.
Norikatsu, Mizumoto, Akira, Takashima
openaire   +2 more sources

Image_2_A population of dermal Langerin+ dendritic cells promote the inflammation in mouse model of atopic dermatitis.tif

, 2022
Cutaneous dendritic cells (DCs) have been implicated in the pathogenesis of atopic dermatitis (AD). However, the specific role of different subsets of DCs has not been well defined.
Wei Li (7081), Chen Zhang (66790), Chunying Xiao (8612091), Jixin Gao (741196), Zhenlai Zhu (11936732), Yixin Luo (712865), Hui Fang (177012), Hongjiang Qiao (6558884), Gang Wang (36685), Meng Fu (307487)   +9 more
core   +1 more source

Langerhans Cells Sense Staphylococcus aureus Wall Teichoic Acid through Langerin To Induce Inflammatory Responses

mBio, 2019
Staphylococcus aureus is a major cause of skin and soft tissue infections and aggravator of the inflammatory skin disease atopic dermatitis (AD [eczema]). Epicutaneous exposure to S.
Rob van Dalen, Jacinto S. De La Cruz Diaz, Matevž Rumpret, Felix F. Fuchsberger, Nienke H. van Teijlingen, Jonas Hanske, Christoph Rademacher, Teunis B. H. Geijtenbeek, Jos A. G. van Strijp, Christopher Weidenmaier, Andreas Peschel, Daniel H. Kaplan, Nina M. van Sorge   +12 more
doaj   +1 more source