Results 81 to 90 of about 8,253 (208)
What contributes to an effective mannose recognition domain? [PDF]
, 2017 In general, carbohydrate-lectin interactions are characterized by high specificity but also low affinity. The main reason for the low affinities are desolvation costs, due to the numerous hydroxy groups present on the ligand, together with the typically ...
Eriş, Deniz +4 more
core +3 more sources
eJHaem, Volume 7, Issue 2, April 2026.ABSTRACT Introduction Histiocytic sarcoma (HS) is a rare neoplasm derived from non‐Langerhans histiocytic cells, exceptionally arising from B‐ALL. Methods We present the case of a child with high‐risk B‐ALL with PAX5 P80R mutation. Results Despite initial remission, a chemoresistant paravertebral mass was identified as HS.
Laetitia Largeaud +12 more
wiley +1 more source
Single Cell Analysis Reveals Dynamic Changes of Distinct Cell Populations in Human Nickel Allergy
Allergy, Volume 81, Issue 4, Page 1138-1148, April 2026.We investigated cell types mediating the early and late inflammatory responses in human Ni2+‐allergy by scRNA‐Seq. Early responsiveness was mainly mediated by TLR4+TAGLN− endothelial cells indirectly activating TLR4−KRT16+ keratinocytes, and CCR7+DCN+ DCs. Late responsiveness was crucially driven by infiltration of KLF2+ central memory T cells and TLR4+
Marc Schmidt +7 more
wiley +1 more source
PLoS ONE, 2019 Langerhans cell histiocytosis (LCH) is characterized by the accumulation of Langerin (CD207)-expressing histiocytes. Mutational activation of mitogen-activated protein kinase pathway genes, in particular BRAF, drives most cases. To test whether activated
David S Nelson +9 more
doaj +1 more source
Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract [PDF]
, 2013 Developing efficacious vaccines against enteric diseases is a global challenge that requires a better understanding of cellular recruitment dynamics at the mucosal surfaces.
Brane, Lucas +14 more
core +2 more sources
11‐year‐old girl presenting with blurred vision and progressive right arm weakness
Brain Pathology, EarlyView.
Trung Toan Tran +6 more
wiley +1 more source
The Plant Journal, Volume 126, Issue 1, April 2026.SUMMARY Pattern recognition receptors (PRRs) function across diverse eukaryotic organisms as a powerful surveillance system to perceive danger signals and to trigger specific adaptive responses. This complex receptor network constitutes the first layer of perception of the innate immune system of plants and mammals.
Gonzalo Vílchez‐Pinto +4 more
wiley +1 more source
Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent [PDF]
Journal of Biological Chemistry, 2017 JBC papers in press 292(3), 862 - 871 (2017).
Hanske, J. +10 more
openaire +4 more sources
Detection of intraepithelial and stromal Langerin and CCR5 positive cells in the human endometrium: potential targets for HIV infection. [PDF]
PLoS ONE, 2011 Both the upper (endocervix and uterus) and lower (ectocervix and vagina) female genital tract mucosa are considered to be target sites for sexual transmission of HIV. There are a few reports on the T cell and antigen-presenting cell distribution in human
Tove Kaldensjö +5 more
doaj +1 more source
Dendritic cells and the extracellular matrix : A challenge for maintaining tolerance/homeostasis [PDF]
, 2015 Supported by The Royal College of Surgeons of Edinburgh. ACKNOWLEDGMENTS We would like to thank the Microscopy Core Facility and the Medical Research Facility at the University of Aberdeen for technical assistance.
Forrester, John +2 more
core +1 more source