Results 81 to 90 of about 5,193 (199)

Detection of intraepithelial and stromal Langerin and CCR5 positive cells in the human endometrium: potential targets for HIV infection. [PDF]

PLoS ONE, 2011
Both the upper (endocervix and uterus) and lower (ectocervix and vagina) female genital tract mucosa are considered to be target sites for sexual transmission of HIV. There are a few reports on the T cell and antigen-presenting cell distribution in human
Tove Kaldensjö, Pernilla Petersson, Anna Tolf, Gareth Morgan, Kristina Broliden, Taha Hirbod   +5 more
doaj   +1 more source

Chronic Pruritic Papular Eruption in an Elderly Man

JEADV Clinical Practice, EarlyView.
Filipe Monteiro, Inês Tribolet‐Abreu, Gustavo Almeida‐Silva, Inês Amaral, Ivânia Soares, Sónia Fernandes, Joana Antunes   +6 more
wiley   +1 more source

Efficacy, safety, and relapse outcomes of MAPK inhibitors in pediatric Langerhans cell histiocytosis: A real‐world study

International Journal of Cancer, Volume 158, Issue 10, Page 2674-2683, 15 May 2026.
What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang, Jing‐jing Sun, Zhi Wan, Xiao‐yu Jing, Xia Guo, Ju Gao   +5 more
wiley   +1 more source

Host Langerin (CD207) is a receptor for Yersinia pestis phagocytosis and promotes dissemination [PDF]

, 2015
Yersinia pestis is a Gram-negative bacterium that causes plague. After Y. pestis overcomes the skin barrier, it encounters antigen-presenting cells (APCs), such as Langerhans and dendritic cells.
박채규
core   +3 more sources

Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state. [PDF]

, 2007
International audienceLangerin is a C-type lectin receptor that recognizes glycosylated patterns on pathogens. Langerin is used to identify human and mouse epidermal Langerhans cells (LCs), as well as migratory LCs in the dermis and the skin draining ...
Leboeuf, Marylene, Ochando, Jordi, Malissen, Bernard, Florent Ginhoux, Bogunovic, Milena, Ginhoux, Florent, Grisotto, Marcos, Hans Snoeck, Helft, Julie, Randolph, Gwendalyn, Kissenpfennig, Adrien, Milena Bogunovic, Matthew P. Collin, Bernard Malissen, Julie Helft, Collin, Matthew P, Adrien Kissenpfennig, Merad, Miriam, Marcos Grisotto, Snoeck, Hans, Jordi Ochando, Michal Abel, Gwendalyn Randolph, Marylene Leboeuf, Abel, Michal, Miriam Merad   +25 more
core   +1 more source

Engagement of a Neighboring Lys Residue by a Salicylaldehyde‐Modified Glycomimetic Ligand Enables Potent and Selective Binding to DC‐SIGN Over L‐SIGN

ChemistryEurope, Volume 4, Issue 5, May 2026.
Mannose derivatives connected to the aminophilic salicylaldehyde tag show high binding affinity for C‐type lectin DC‐SIGN, favored by an imine bond with a protein's Lys residue in the ligand binding site. This reversible‐covalent binding interaction enables ligand selectivity for DC‐SIGN over the closely related L‐SIGN.
Sara Pollastri, Clara Delaunay, Giulia Antonini, Carine Froment, Michel Thépaut, Davide Pasquali, Sarah Mazzotta, Laura Belvisi, Julien Marcoux, Franck Fieschi, Alberto Dal Corso, Anna Bernardi   +11 more
wiley   +1 more source

Editorial: Faux amis: Langerin-expressing DC in humans and mice [PDF]

Journal of Leukocyte Biology, 2015
Discussion on the identification of Langerin+ DC populations in humans.
openaire   +2 more sources

Ezh2 Controls Skin Tolerance through Distinct Mechanisms in Different Subsets of Skin Dendritic Cells

iScience, 2018
Summary: Ezh2, a well-established epigenetic repressor, can down-regulate leukocyte inflammatory responses, but its role in cutaneous health remains elusive.
Jia Tong Loh, Thomas Jun Feng Lim, Kyoko Ikumi, Takuma Matoba, Baptiste Janela, Merry Gunawan, Tatsuya Toyama, Maegan Bunjamin, Lai Guan Ng, Michael Poidinger, Akimichi Morita, Florent Ginhoux, Sayuri Yamazaki, Kong-Peng Lam, I-hsin Su   +14 more
doaj   +1 more source

Production of monoclonal antibodies that recognize the extracellular domain of mouse Langerin/CD207 [PDF]

Journal of Immunological Methods, 2007
Langerin CD207 is a type II transmembrane protein. It is responsible for the formation of Birbeck granules, which are intracellular organelles within Langerhans cells, the dendritic cells of stratified squamous epithelia like the epidermis. Because current anti-CD207 antibodies have limitations, we prepared new monoclonals by immunizing rats with the ...
Cheong, Cheolho, Idoyaga, Juliana, Do, Yoonkyung, Pack, Maggi, Park, Sung Ho, Lee, Haekyung, Kang, Young-Sun, Choi, Jae-Hoon, Kim, Jae Y., Bonito, Anthony, Inaba, Kayo, Yamazaki, Sayuri, Steinman, Ralph M., Park, Chae Gyu   +13 more
openaire   +3 more sources

Novel Approaches for Investigating Host Responses to HIV Infection in Ex Vivo Human Genital Tissues

American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Understanding local immune responses and the structural integrity of the genital mucosal barrier is essential for advancing knowledge of both susceptibility to sexual HIV transmission and the pathogenesis of chronic HIV infection. This review highlights innovative methodologies for investigating host responses to HIV infection using ex vivo ...
Mathias Franzén Boger, Vilde Kaldhusdal, Kristina Broliden   +2 more
wiley   +1 more source