Results 81 to 90 of about 633,545 (282)
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Recherches en Éducation, 2013 This text presents a descriptive and comprehensive research, based on professional didactic (Pastré, Mayen, Vergnaud, 2006, Vinatier, 2009) and analysis of the speeches-in-interaction (Kerbrat-Orecchioni, 2005), especially teachers’ speech acts (Austin ...
Éric Saillot
doaj +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Recherches en Éducation, 2016 Through this paper, we propose to draw up a model of philosophical discussion as a particular situation of communication, in order to understand the functioning of the communication in these spaces of collective thinking.
Aline Auriel
doaj +1 more source
Human-Machine Multi-Turn Language Dialogue Interaction Based on Deep Learning. [PDF]
Micromachines (Basel), 2022 Ke X, Hu P, Yang C, Zhang R.
europepmc +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Une lecture grammaticale de séquences choisies dans les échanges philosophiques
Recherches en Éducation, 2016 This paper proposes an analysis of continuous texts based on a specific corpus made of philosophical discussions. The aim of this syntactic study is to show the inner organization of textual extracts, from their regularities to their variations.
Mylène Blasco
doaj +1 more source
The Embodied Crossmodal Self Forms Language and Interaction: A Computational Cognitive Review. [PDF]
Front Psychol, 2021 Röder F +4 more
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Recherches en Éducation, 2016 The objective of our study was to characterize the processes of conceptualization within the discussions with philosophical aim in primary education. In this end, we have integrated the concept of “dialogism” (Bakhtin, 1978, 1984) now widely used in the ...
Philippe Roiné
doaj +1 more source