Results 71 to 80 of about 17,625 (221)

Inhibition of cholesterol biogenesis by arsenite: preparation of labeled lanosterol*

Journal of Lipid Research, 1961
When mevalonic acid-2-C14 was incubated with rat liver homogenate with the usual cofactors plus 10−3 M arsenite, the formation of labeled cholesterol was inhibited and labeled lanosterol accumulated.
Mary L. Moller, T.T. Tchen
doaj   +1 more source

Sterols associated with small unilamellar vesicles (SUVs): intrinsic mobility role for 1H NMR detection.

, 2014
International audienceSmall unilamellar vesicles (SUVs) of phospholipids are often used as a membrane model system for studying the interaction of molecules.
Bondon, Arnaud, Da Costa, Grégory, Mouret, Liza   +2 more
core   +3 more sources

The zinc cluster proteins Upc2 and Ecm22 promote filamentation in Saccharomyces cerevisiae by sterol biosynthesis-dependent and -independent pathways. [PDF]

, 2015
The transition between a unicellular yeast form to multicellular filaments is crucial for budding yeast foraging and the pathogenesis of many fungal pathogens such as Candida albicans.
Höfken, T, Woods, K
core   +1 more source

Development of an analytical method for detecting triterpene alcohols in camellia oil and evaluation of their anti‐inflammatory effects

JSFA reports, Volume 6, Issue 3, Page 62-72, March 2026.
Abstract Background Camellia oil is a characteristic Chinese plant oil and is hailed as “the olive oil of the East”. However, there is a significant difference in the active ingredient between it and olive oil, which consequently leads to different effects.
Hengguang Cheng, Qing Jiang, Xiaoxia Li, Yunjie Jiang, Tinghuan Fang, Lirong Tang   +5 more
wiley   +1 more source

Mycochemical Diversity and Therapeutic Potential of Hymenochaetoid Fungi from Central Asia: Regional and Global Perspectives

New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov, Milena Rašeta, Sylvie Rapior, Manzura Yarasheva, Oksana Mykchaylova, Rustamjon Allaberdiev, Şule İnci, Dilfuza Berdieva, Arshad Mehmood Abbasi, Shikhnazar Khodjaev, Dian‐Ming Hu, Weijun Yang, Abudujilili Abuduaini, Maria Letizia Taddei, Mengcen Wang, Islomjon Urinboev, Jiajia Chen   +16 more
wiley   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, Volume 22, Issue 16, 17 March 2026.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Lanosterol regulates abnormal amyloid accumulation in LECs through the mediation of cholesterol pathway metabolism

Biochemistry and Biophysics Reports
Age-related cataract (ARC) is the predominant cause of global blindness, linked to the progressive aging of the lens, oxidative stress, perturbed calcium homeostasis, hydration irregularities, and modifications in crystallin proteins. Currently, surgical
Yingxue Su, Danyuan Sun, Chen Cao, Yandong Wang   +3 more
doaj   +1 more source

Study on anti-tumor activity of itraconazole in colon cancer [PDF]

E3S Web of Conferences, 2019
Itraconazole is a common antifungal drug, which inhibiting lanosterol 14 alpha-demethylase, interfering with lanosterol convert to ergosterol or cholesterol, thereby affecting the synthesis of fungal cell membranes.
Li Xiaoqi, Shan Jingbo, Jin Lijun, Li Xinyu, Zhou Sa, Ma Wenjian   +5 more
doaj   +1 more source

Analysis of ergosterol and gene expression profiles of sterol ∆5,6-desaturase (ERG3) and lanosterol 14α-demethylase (ERG11) in Candida albicans treated with carvacrol [PDF]

, 2018
Introduction: Usually, for treatment of fungal infections, antifungals such as azoles are used, but one of the biggest problems faced in clinical practice is the emergence of resistance for most of these drugs.
Alizadeh, Fahimeh., Esfandyari, Samad., Khodavandi, Alireza., Nouripour-Sisakht, Sadegh.   +3 more
core   +2 more sources

In Vitro Activities of Five Antifungal Drugs Against Conidia and Sclerotic Cells of Chromoblastomycosis Agent Fonsecaea spp

Microbiology and Immunology, Volume 70, Issue 3, Page 139-147, March 2026.
ABSTRACT Chromoblastomycosis (CBM) is a chronic skin and subcutaneous infection mainly caused by Fonsecaea pedrosoi, a dematiaceous fungus with various morphotypes. Characteristic sclerotic cells—globe‐shaped, multiseptated and pigmented—are found in lesions of infected individuals, though their differentiation in the host remains poorly understood. To
Aline Barral Takahashi, Daniella Paternostro de Araújo Grisólia, Moises Batista da Silva, Naila Ferreira da Cruz, Sâmela Miranda da Silva, Patrícia Fagundes da Costa, Claudio Guedes Salgado   +6 more
wiley   +1 more source