Results 61 to 70 of about 6,528 (248)
Duramycin-induced calcium release in cancer cells [PDF]
, 2015 Introduction: Duramycin through binding with phosphatidylethanolamine (PE) has shown potential to be an effective anti-tumour agent. However its mode of action in relation to tumour cells is not fully understood.
Broughton, Laura J. +3 more
core +1 more source
Lantibiotics as probes for phosphatidylethanolamine [PDF]
Amino Acids, 2009 Phosphatidylethanolamine (PE) is a major component in the mammalian plasma membrane. It is present mainly in the inner leaflet of the membrane bilayer in a viable, typical mammalian cell. However, accumulating evidence indicates that a number of biological events involve PE externalization.
openaire +2 more sources
Immunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle +6 more
wiley +1 more source
Identification of essential amino acid residues in the nisin dehydratase NisB
Frontiers in Microbiology, 2015 Nisin is a posttranslationally-modified antimicrobial peptide that has the ability to induce its own biosynthesis. Serines and threonines in the modifiable core peptide part of precursor nisin are dehydrated to dehydroalanines and dehydrobutyrines by the
Rustem eKhusainov +5 more
doaj +1 more source
, 2015 Bacteriocins are peptide-derived molecules produced by bacteria, whose recently-discovered functions include virulence factors and signalling molecules as well as their better known roles as antibiotics.
Freed, Stefan D +3 more
core +1 more source
BAGEL:a web-based bacteriocin genome mining tool [PDF]
, 2006 A common problem in the annotation of open reading frames (ORFs) is the identification of genes that are functionally similar but have limited or no sequence homology.
Bijlsma, Jetta J. E. +4 more
core +2 more sources
Epidermin and gallidermin: Staphylococcal lantibiotics
International Journal of Medical Microbiology, 2014 The Staphylococcus epidermidis derived epidermin was the first lantibiotic that has been shown to be ribosomally synthesized and posttranslationally modified. Together with gallidermin, produced by Staphylococcus gallinarum, they belong to the large class of cationic antimicrobial peptides (CAMPs) that act against a broad spectrum of Gram-positive ...
Perconti, Silvana +4 more
openaire +3 more sources
Nukacin ISK-1, a Bacteriostatic Lantibiotic [PDF]
Antimicrobial Agents and Chemotherapy, 2009 ABSTRACT We determined the mode of action of nukacin ISK-1. It did not cause membrane potential dissipation or the efflux of ATP or K + ions from the cells of a sensitive bacterial strain; however, it blocked the membrane depolarization activity of nisin. Nukacin ISK-1-treated cells had single arrangements
Sikder M, Asaduzzaman +5 more
openaire +2 more sources
Advanced Science, Volume 13, Issue 12, 27 February 2026.Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács +9 more
wiley +1 more source
Expression of the lantibiotic mersacidin in Bacillus amyloliquefaciens FZB42. [PDF]
PLoS ONE, 2011 UNLABELLED: Lantibiotics are small peptide antibiotics that contain the characteristic thioether amino acids lanthionine and methyllanthionine. As ribosomally synthesized peptides, lantibiotics possess biosynthetic gene clusters which contain the ...
Anna Maria Herzner +10 more
doaj +1 more source