Results 21 to 30 of about 14,758 (206)

Lethal Infection of Lassa Virus Isolated from a Human Clinical Sample in Outbred Guinea Pigs without Adaptation

open access: yesmSphere, 2019
Lassa virus (LASV), a member of the family Arenaviridae, is the causative agent of Lassa fever. Lassa virus is endemic in West African countries, such as Nigeria, Guinea, Liberia, and Sierra Leone, and causes outbreaks annually.
Junki Maruyama   +6 more
doaj   +1 more source

Human platelets and their capacity of binding viruses: Meaning and challenges? [PDF]

open access: yes, 2015
Blood platelets are first aimed at ensuring primary hemostasis. Beyond this role, they have been acknowledged as having functions in the maintenance of the vascular arborescence and, more recently, as being also innate immune cells, devoted notably to ...
Chabert, Adrien   +6 more
core   +2 more sources

One-Year Retrospective Review of Psychiatric Consultations in Lassa Fever, Southern Nigeria

open access: yesEmerging Infectious Diseases, 2020
We conducted a retrospective review of psychiatric consultations for hospitalized patients with Lassa fever in southern Nigeria. Ten (8.8%) of 113 patients had psychiatric consultations.
Esther O. Okogbenin   +5 more
doaj   +1 more source

Lassa fever and infection control: Knowledge, attitudes and practice in a University Teaching Hospital in Uyo, Nigeria

open access: yesIbom Medical Journal, 2017
Context: Lassa fever is a deadly viral hemorrhagic disease that is endemic in Nigeria with recurrent outbreaks that often affect healthcare workers. Hospital infection control can potentially limit the impact of outbreaks of this disease in healthcare ...
Ekuma AE, Akpan IS
doaj   +1 more source

Using modelling to disentangle the relative contributions of zoonotic and anthroponotic transmission: the case of lassa fever. [PDF]

open access: yes, 2015
BACKGROUND: Zoonotic infections, which transmit from animals to humans, form the majority of new human pathogens. Following zoonotic transmission, the pathogen may already have, or may acquire, the ability to transmit from human to human. With infections
Cunningham, Andrew A   +11 more
core   +4 more sources

Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples [PDF]

open access: yes, 2015
We have developed a robust RNA sequencing method for generating complete de novo assemblies with intra-host variant calls of Lassa and Ebola virus genomes in clinical and biological samples.
Andersen, Kristian G   +26 more
core   +1 more source

Capacity building permitting comprehensive monitoring of a severe case of Lassa hemorrhagic fever in Sierra Leone with a positive outcome: Case Report

open access: yesVirology Journal, 2011
Lassa fever is a neglected tropical disease with a significant impact on the health care system of endemic West African nations. To date, case reports of Lassa fever have focused on laboratory characterisation of serological, biochemical and molecular ...
Fonnie Mbalu   +13 more
doaj   +1 more source

An overview of Lassa fever

open access: yesWikiJournal of Medicine, 2019
Lassa fever is a viral hemorrhagic fever caused by Lassa virus (Lassa mammarenavirus), a negative-sense single-stranded RNA virus of the Arenaviridae family. In most cases Lassa virus infection is asymptomatic (presenting no symptom). When symptomatic it
Abdulmutalab Musa
doaj   +1 more source

Descriptive epidemiology of Lassa fever in Nigeria, 2012-2017

open access: yesThe Pan African Medical Journal, 2020
INTRODUCTION: Lassa fever, an acute viral hemorrhagic zoonotic disease is endemic in some parts of Nigeria. The disease alert and outbreak threshold are known; however, there has been a shift from the previous seasonal transmission pattern to an all year-
Onyebuchi Augustine Okoro   +8 more
doaj   +1 more source

Treatment of Marburg and Ebola hemorrhagic fevers: A strategy for testing new drugs and vaccines under outbreak conditions. [PDF]

open access: yes, 2008
The filoviruses, Marburg and Ebola, have the dubious distinction of being associated with some of the highest case-fatality rates of any known infectious disease-approaching 90% in many outbreaks.
A.G. Sprecher   +105 more
core   +2 more sources

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