Results 41 to 50 of about 8,755 (175)
ABSTRACT Introduction Antimicrobial resistance (AMR) is a growing public health threat that disproportionately affects African countries due to high infectious disease burdens, widespread antimicrobial misuse, weak health systems, inadequate diagnostic capacity, and fragmented surveillance infrastructure.
Ameh Wisdom Owoicho, Majani Edward
wiley +1 more source
How Host Phylogeny, Diet, and Habitat Affect Gut Microbial Diversity in Wild Snakes
Gut microbiota plays critical roles in host digestion, immune regulation, neurochemical signaling, and metabolic homeostasis. Based on wild snakes (73 individuals from 23 species) from China, we explored the composition, characteristics, and functions of gut microbes across different groups using fecal metagenomic samples; further we explored the ...
Jiaqi Zhang +7 more
wiley +1 more source
We previously developed optimized DNA vaccines against both Lassa fever and Ebola hemorrhagic fever viruses and demonstrated that they were protective individually in guinea pig and nonhuman primate models.
Kathleen A. Cashman +8 more
doaj +1 more source
Sexual and reproductive health and rights in anticipatory action for disasters
Abstract An examination of the incorporation of sexual and reproductive health and rights (SRHR) in anticipatory action (AA) reveals the latter's potential to strengthen disaster response by addressing pre‐existing inequalities and marginalised needs.
Ellie Edmond Shimmin, Emmanuel Raju
wiley +1 more source
Cell entry of many enveloped viruses occurs by engagement with cellular receptors, followed by internalization into endocytic compartments and pH-induced membrane fusion.
Hadar Israeli +4 more
doaj +1 more source
Lassa antiviral LHF-535 protects guinea pigs from lethal challenge
LHF-535 is a small molecule antiviral currently in development for the treatment of Lassa fever, a zoonotic disease endemic in West Africa that generates significant morbidity and mortality.
Kathleen A. Cashman +8 more
doaj +1 more source
Research Direction and Science Evaluation: The Role of Coherence and Alignment
ABSTRACT The decisions of funding agencies greatly influence the direction of scientific research; however, our understanding of how applicants' research directions affect the selection process remains limited. In this study, we investigate how a project's coherence with a scientist's previous work and its alignment with current scientific trends ...
Charles Ayoubi +3 more
wiley +1 more source
Lassa Virus in Pygmy Mice, Benin, 2016–2017
Lassa virus has been identified in 3 pygmy mice, Mus baoulei, in central Benin. The glycoprotein and nucleoprotein sequences cluster with the Togo strain. These mice may be a new reservoir for Lassa virus in Ghana, Togo, and Benin.
Anges Yadouleton +14 more
doaj +1 more source
High crossreactivity of human T cell responses between Lassa virus lineages.
Lassa virus infects hundreds of thousands of people each year across rural West Africa, resulting in a high number of cases of Lassa fever (LF), a febrile disease associated with high morbidity and significant mortality.
Brian M Sullivan +28 more
doaj +1 more source
Pathogens that Cause Illness Clinically Indistinguishable from Lassa Fever, Nigeria, 2018
During the 2018 Lassa fever outbreak in Nigeria, samples from patients with suspected Lassa fever but negative Lassa virus PCR results were processed through custom gene expression array cards and metagenomic sequencing.
Jonathan W. Ashcroft +22 more
doaj +1 more source

