Results 41 to 50 of about 8,755 (175)

Antimicrobial Stewardship, Laboratory Surveillance, and Quality Management in Africa: A Narrative Review of Challenges and Opportunities for Integrated AMR Control

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Introduction Antimicrobial resistance (AMR) is a growing public health threat that disproportionately affects African countries due to high infectious disease burdens, widespread antimicrobial misuse, weak health systems, inadequate diagnostic capacity, and fragmented surveillance infrastructure.
Ameh Wisdom Owoicho, Majani Edward
wiley   +1 more source

How Host Phylogeny, Diet, and Habitat Affect Gut Microbial Diversity in Wild Snakes

open access: yesEcology and Evolution, Volume 16, Issue 7, July 2026.
Gut microbiota plays critical roles in host digestion, immune regulation, neurochemical signaling, and metabolic homeostasis. Based on wild snakes (73 individuals from 23 species) from China, we explored the composition, characteristics, and functions of gut microbes across different groups using fecal metagenomic samples; further we explored the ...
Jiaqi Zhang   +7 more
wiley   +1 more source

DNA vaccines elicit durable protective immunity against individual or simultaneous infections with Lassa and Ebola viruses in guinea pigs

open access: yesHuman Vaccines & Immunotherapeutics, 2017
We previously developed optimized DNA vaccines against both Lassa fever and Ebola hemorrhagic fever viruses and demonstrated that they were protective individually in guinea pig and nonhuman primate models.
Kathleen A. Cashman   +8 more
doaj   +1 more source

Sexual and reproductive health and rights in anticipatory action for disasters

open access: yesDisasters, Volume 50, Issue 3, July 2026.
Abstract An examination of the incorporation of sexual and reproductive health and rights (SRHR) in anticipatory action (AA) reveals the latter's potential to strengthen disaster response by addressing pre‐existing inequalities and marginalised needs.
Ellie Edmond Shimmin, Emmanuel Raju
wiley   +1 more source

Mapping of the Lassa virus LAMP1 binding site reveals unique determinants not shared by other old world arenaviruses.

open access: yesPLoS Pathogens, 2017
Cell entry of many enveloped viruses occurs by engagement with cellular receptors, followed by internalization into endocytic compartments and pH-induced membrane fusion.
Hadar Israeli   +4 more
doaj   +1 more source

Lassa antiviral LHF-535 protects guinea pigs from lethal challenge

open access: yesScientific Reports, 2022
LHF-535 is a small molecule antiviral currently in development for the treatment of Lassa fever, a zoonotic disease endemic in West Africa that generates significant morbidity and mortality.
Kathleen A. Cashman   +8 more
doaj   +1 more source

Research Direction and Science Evaluation: The Role of Coherence and Alignment

open access: yesJournal of Economics &Management Strategy, Volume 35, Issue 3, Page 437-474, Fall 2026.
ABSTRACT The decisions of funding agencies greatly influence the direction of scientific research; however, our understanding of how applicants' research directions affect the selection process remains limited. In this study, we investigate how a project's coherence with a scientist's previous work and its alignment with current scientific trends ...
Charles Ayoubi   +3 more
wiley   +1 more source

Lassa Virus in Pygmy Mice, Benin, 2016–2017

open access: yesEmerging Infectious Diseases, 2019
Lassa virus has been identified in 3 pygmy mice, Mus baoulei, in central Benin. The glycoprotein and nucleoprotein sequences cluster with the Togo strain. These mice may be a new reservoir for Lassa virus in Ghana, Togo, and Benin.
Anges Yadouleton   +14 more
doaj   +1 more source

High crossreactivity of human T cell responses between Lassa virus lineages.

open access: yesPLoS Pathogens, 2020
Lassa virus infects hundreds of thousands of people each year across rural West Africa, resulting in a high number of cases of Lassa fever (LF), a febrile disease associated with high morbidity and significant mortality.
Brian M Sullivan   +28 more
doaj   +1 more source

Pathogens that Cause Illness Clinically Indistinguishable from Lassa Fever, Nigeria, 2018

open access: yesEmerging Infectious Diseases, 2022
During the 2018 Lassa fever outbreak in Nigeria, samples from patients with suspected Lassa fever but negative Lassa virus PCR results were processed through custom gene expression array cards and metagenomic sequencing.
Jonathan W. Ashcroft   +22 more
doaj   +1 more source

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