Results 41 to 50 of about 17,001 (224)

Molecular confirmation of Lassa fever imported into Ghana

African Journal of Laboratory Medicine, 2016
Background: Recent reports have shown an expansion of Lassa virus from the area where it was first isolated in Nigeria to other areas of West Africa.
Joseph H.K. Bonney, Edward O. Nyarko, Sally-Ann Ohene, Joseph Amankwa, Ralph K. Ametepi, Shirley C. Nimo-Paintsil, Badu Sarkodie, Prince Agbenohevi, Michael Adjabeng, Nicholas N.A. Kyei, Samuel Bel-Nono, William K. Ampofo   +11 more
doaj   +1 more source

Ebola virus disease epidemic in West Africa: Lessons learned and issues arising from West African countries [PDF]

, 2015
© Royal College of Physicians 2015. All rights reserved.The current Ebola virus disease (EVD) outbreak ravaging three nations in West Africa has affected more than 14,000 persons and killed over 5,000.
Akpalu, AK, Foster, M, Ka, MM, McConnochie, M, Oleribe, OO, Salako, BL, Taylor-Robinson, SD   +6 more
core   +1 more source

Development of a minigenome cassette for Lettuce necrotic yellows virus: A first step in rescuing a plant cytorhabdovirus [PDF]

, 2020
Rhabdoviruses are enveloped negative-sense RNA viruses that have numerous biotechnological applications. However, recovering plant rhabdoviruses from cDNA remains difficult due to technical difficulties such as the need for concurrent in planta ...
Drake, P, Ibrahim, AEC, Ma, J, Van Dolleweerd, CJ   +3 more
core   +1 more source

Phylogeography of Lassa Virus in Nigeria [PDF]

Journal of Virology, 2019
Lassa virus is the causative agent of Lassa fever, a viral hemorrhagic fever with a case fatality rate of approximately 30% in Africa. Previous studies disclosed a geographical pattern in the distribution of Lassa virus strains and a westward movement of the virus across West Africa during evolution.
Ehichioya, Deborah U., Dellicour, Simon, Pahlmann, Meike, Rieger, Toni, Oestereich, Lisa, Becker-Ziaja, Beate, Cadar, Daniel, Ighodalo, Yemisi, Olokor, Thomas, Omomoh, Emmanuel, Oyakhilome, Jennifer, Omiunu, Racheal, Agbukor, Jacqueline, Ebo, Benevolence, Aiyepada, John, Ebhodaghe, Paulson, Osiemi, Blessing, Ehikhametalor, Solomon, Akhilomen, Patience, Airende, Michael, Esumeh, Rita, Muoebonam, Ekene, Giwa, Rosemary, Ekanem, Anieno, Igenegbale, Ganiyu, Odigie, George, Okonofua, Grace, Enigbe, Racheal, Yerumoh, Edna Omonegho, Pallasch, Elisa, Bockholt, Sabrina, Kafetzopoulou, Liana E., Duraffour, Sophie, Okokhere, Peter O., Akpede, George O., Okogbenin, Sylvanus A., Odia, Ikponmwosa, Aire, Chris, Akpede, Nosa, Tobin, Ekaete, Ogbaini-Emovon, Ephraim, Lemey, Philippe, Adomeh, Donatus, Asogun, Danny A., Guenther, Stephan   +44 more
openaire   +4 more sources

High-Resolution Structure of the N-Terminal Endonuclease Domain of the Lassa Virus L Polymerase in Complex with Magnesium Ions [PDF]

, 2014
Lassa virus (LASV) causes deadly hemorrhagic fever disease for which there are no vaccines and limited treatments. LASV-encoded L polymerase is required for viral RNA replication and transcription.
Dong, Changjiang, Dong, Haohao, Huang, Qinfeng, Liang, Yuying, Ly, Hinh, Wallat, Gregor D., Wang, Wenjian   +6 more
core   +6 more sources

New Hosts of The Lassa Virus [PDF]

Scientific Reports, 2016
Abstract Lassa virus (LASV) causes a deadly haemorrhagic fever in humans, killing several thousand people in West Africa annually. For 40 years, the Natal multimammate rat, Mastomys natalensis , has been assumed to be the sole host of LASV.
Olayemi, Ayodeji, Cadar, Daniel, Magassouba, N. Faly, Obadare, Adeoba, Kourouma, Fode, Oyeyiola, Akinlabi, Fasogbon, Samuel, Igbokwe, Joseph, Rieger, Toni, Bockholt, Sabrina, Jerome, Hanna, Schmidt-Chanasit, Jonas, Garigliany, Mutien-Marie, Lorenzen, Stephan, Igbahenah, Felix, Fichet, Jean-Nicolas, Ortsega, Daniel, Omilabu, Sunday, Gunther, Stephan, Fichet-Calvet, Elisabeth   +19 more
openaire   +3 more sources

Family-specific degenerate primer design: a tool to design consensus degenerated oligonucleotides [PDF]

, 2013
Designing degenerate PCR primers for templates of unknown nucleotide sequence may be a very difficult task. In this paper, we present a new method to design degenerate primers, implemented in family-specific degenerate primer design (FAS-DPD) computer ...
Borio, Cristina Silvia, Ghiringhelli, Pablo Daniel, Goñi, Sandra Elizabeth, Iserte, Javier Alonso, Lozano, Mario Enrique, Stephan, Betina Inés   +5 more
core   +3 more sources

Diversity in responses to oncolytic Lassa-vesicular stomatitis virus in patient-derived glioblastoma cells

Molecular Therapy: Oncolytics, 2021
The difficulty of glioblastoma treatment makes it a good candidate for novel therapies, such as oncolytic viruses. Vesicular stomatitis virus expressing Lassa virus glycoprotein (Lassa-VSV) showed significant promise in animal models using established ...
Teddy E. Kim, Shelby Puckett, Kailong Zhang, Denise M. Herpai, David A. Ornelles, John N. Davis, Anthony N. van den Pol, Waldemar Debinski, Douglas S. Lyles   +8 more
doaj   +1 more source

Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples [PDF]

, 2015
We have developed a robust RNA sequencing method for generating complete de novo assemblies with intra-host variant calls of Lassa and Ebola virus genomes in clinical and biological samples.
Andersen, Kristian G, Berlin, Aaron, Birren, Bruce W, Busby, Michele, Ehiane, Philomena E, England, Eleina, Folarin, Onikepe, Garry, Robert F, Gire, Stephen K, Gladden, Adrianne D, Gnirke, Andreas, Goba, Augustine, Grant, Donald S, Happi, Christian, Hensley, Lisa, Honko, Anna, Kahn, S Humarr, Levin, Joshua Z, Malboeuf, Christine M, Matranga, Christian B, Mikkelsen, Tarjei S, Moses, Lina M, Odia, Ikponmwonsa, Sabeti, Pardis C, Stremlau, Matthew, Tewhey, Ryan, Winnicki, Sarah   +26 more
core   +1 more source

Bayesian estimation of Lassa virus epidemiological parameters: Implications for spillover prevention using wildlife vaccination.

PLoS Neglected Tropical Diseases, 2020
Lassa virus is a significant burden on human health throughout its endemic region in West Africa, with most human infections the result of spillover from the primary rodent reservoir of the virus, the natal multimammate mouse, M. natalensis.
Scott L Nuismer, Christopher H Remien, Andrew J Basinski, Tanner Varrelman, Nathan Layman, Kyle Rosenke, Brian Bird, Michael Jarvis, Peter Barry, Patrick W Hanley, Elisabeth Fichet-Calvet   +10 more
doaj   +1 more source