Results 51 to 60 of about 8,755 (175)
Lassa virus protein-protein interactions as mediators of Lassa fever pathogenesis. [PDF]
Abstract Viral hemorrhagic Lassa fever (LF), caused by Lassa virus (LASV), is a significant public health concern endemic in West Africa with high morbidity and mortality rates, limited treatment options, and potential for international spread.
Jan S +4 more
europepmc +4 more sources
Addressing Climate Driven Vector‐Borne Disease in West Africa
ABSTRACT Introduction Vector‐borne diseases (VBDs) pose a significant public health threat in West Africa, contributing to substantial morbidity and mortality, particularly among vulnerable populations. This region is highly susceptible to the effects of climate change due to its geographical location, dependence on rain‐fed agriculture, and fragile ...
Majani Edward +3 more
wiley +1 more source
Improving the Breadth of the Host’s Immune Response to Lassa Virus
In 2017, the global Coalition for Epidemic Preparedness (CEPI) declared Lassa virus disease to be one of the world’s foremost biothreats. In January 2018, World Health Organization experts met to address the Lassa biothreat.
Juan Carlos Zapata +3 more
doaj +1 more source
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterised by progressive muscle weakness in both bulbar and extremity muscles, leading to a diverse clinical phenotype with motor and non‐motor symptoms. Cerebrospinal fluid (CSF) from sporadic ALS patients were analysed for proteomics content and revealed altered inflammatory and ...
Eleonora Sabetta +8 more
wiley +1 more source
Spreading Speed for a Vector‐Borne Disease System on Non‐Coincident Straight Infinite Cylinders
ABSTRACT Vector‐borne diseases remain an increasing global public health concern. In this work, we investigate the spreading speed of vector‐borne disease via a four‐component reaction–diffusion system posed on non‐coincident straight infinite cylinders, which stands for an unconventional spatial configuration.
Arnaud Ducrot +2 more
wiley +1 more source
ABSTRACT Pet dogs with naturally occurring cancers provide valuable models for comparative oncology and pathology tumour registries offer a powerful resource for onco‐epidemiological research. Here, we analysed the Small Animal Veterinary Surveillance Network (SAVSNET) pathology‐based tumour registry (PTR), one of the largest veterinary tumour ...
José Rodríguez +9 more
wiley +1 more source
Detection of Antibody and Antigen for Lassa Virus Nucleoprotein in Monkeys from Southern Nigeria
Lassa fever is a deadly viral haemorrhagic fever caused by Lassa Virus (LASV). Rodents, especially, Mystomys natalensis, are the known reservoirs of LASV and humans are the defined hosts.
Bamidele Nyemike Ogunro +6 more
doaj +1 more source
A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang +13 more
wiley +1 more source
Assessing the Environmental Drivers of Lassa Fever in West Africa: A Systematic Review
The spread of Lassa virus in West Africa is reliant on the abundance and distribution of its rodent host reservoirs. While the impact of environmental change on viral spread has been studied for many zoonotic viruses, there is still a limited ...
Natalie A. Davis +4 more
doaj +1 more source
Lassa virus (LASV) causes a severe, often fatal hemorrhagic disease in regions in Africa where the disease is endemic, and approximately 30% of patients develop sudden-onset sensorineural hearing loss after recovering from acute disease.
Kathleen A. Cashman +8 more
doaj +1 more source

