Results 31 to 40 of about 10,303 (224)

Lassa Fever Encephalopathy: Lassa Virus in Cerebrospinal Fluid but Not in Serum [PDF]

The Journal of Infectious Diseases, 2001
The pathogenesis of neurologic complications of Lassa fever is poorly understood. A Nigerian patient had fever, disorientation, seizures, and blood-brain barrier dysfunction, and Lassa virus was found in cerebrospinal fluid (CSF) but not in serum.
S, Günther, B, Weisner, A, Roth, T, Grewing, M, Asper, C, Drosten, P, Emmerich, J, Petersen, M, Wilczek, H, Schmitz   +9 more
openaire   +2 more sources

Molecular confirmation of Lassa fever imported into Ghana

African Journal of Laboratory Medicine, 2016
Background: Recent reports have shown an expansion of Lassa virus from the area where it was first isolated in Nigeria to other areas of West Africa.
Joseph H.K. Bonney, Edward O. Nyarko, Sally-Ann Ohene, Joseph Amankwa, Ralph K. Ametepi, Shirley C. Nimo-Paintsil, Badu Sarkodie, Prince Agbenohevi, Michael Adjabeng, Nicholas N.A. Kyei, Samuel Bel-Nono, William K. Ampofo   +11 more
doaj   +1 more source

Immunobiology of Ebola and Lassa virus infections [PDF]

Nature Reviews Immunology, 2017
Two of the most important contemporary emerging viruses that affect human health in Africa are Ebola virus (EBOV) and Lassa virus (LASV). The 2013-2016 West African outbreak of EBOV was responsible for more than 11,000 deaths, primarily in Guinea, Sierra Leone and Liberia.
Joseph B, Prescott, Andrea, Marzi, David, Safronetz, Shelly J, Robertson, Heinz, Feldmann, Sonja M, Best   +5 more
openaire   +2 more sources

Prevalence and risk factors of Lassa seropositivity in inhabitants of the forest region of Guinea: a cross-sectional study.

, 2009
BACKGROUND: Lassa fever is a viral hemorrhagic fever endemic in West Africa. The reservoir host of the virus is a multimammate rat, Mastomys natalensis.
Fichet-Calvet, Elisabeth, Elisabeth Fichet-Calvet, Philippe J Guerin, Magassouba, N'Faly, Koulemou, K, Lewis, R, Kekoura Koulemou, Rebecca F Grais, Guerin, Philippe J, Rosamund Lewis, Grais, Rebecca F., Guerin, Philippe J., Fichet-Calvet, E, Solen Kernéis, Grais, RF, Lamine Koivogui, Guerin, PJ, Philippe J. Guerin, N'Faly Magassouba, Grais, Rebecca F, Magassouba, N, Kernéis, Solen, Koivogui, Lamine, Lewis, Rosamund, Kernéis, S, Rebecca F. Grais, Koulemou, Kekoura, Aplogan, Aristide, Koivogui, L, Aplogan, A, Aristide Aplogan   +30 more
core   +1 more source

Diversity in responses to oncolytic Lassa-vesicular stomatitis virus in patient-derived glioblastoma cells

Molecular Therapy: Oncolytics, 2021
The difficulty of glioblastoma treatment makes it a good candidate for novel therapies, such as oncolytic viruses. Vesicular stomatitis virus expressing Lassa virus glycoprotein (Lassa-VSV) showed significant promise in animal models using established ...
Teddy E. Kim, Shelby Puckett, Kailong Zhang, Denise M. Herpai, David A. Ornelles, John N. Davis, Anthony N. van den Pol, Waldemar Debinski, Douglas S. Lyles   +8 more
doaj   +1 more source

Putting Rodents at the Center of One Health Programs: A Narrative Synthesis

Integrative Zoology, EarlyView.
Rodents link human, animal, and environmental health across diverse ecosystems. Rodent diversity underpins both zoonotic disease risk and ecosystem function. Environmental change reshapes rodent communities and spillover dynamics. Rodents act as reservoirs, amplifiers, and sentinels of emerging pathogens.
Steven R. Belmain
wiley   +1 more source

Mutational Analysis of the Lassa Virus Promoter [PDF]

Journal of Virology, 2006
ABSTRACT The promoter sequences directing viral gene expression and genome replication of arenaviruses reside within the 3′ and 5′ termini of each RNA segment. The terminal 19 nucleotides at both ends are highly conserved among all arenavirus species and are almost completely complementary to each other. This study aimed at characterizing the
Meike, Hass, Martina, Westerkofsky, Stefanie, Müller, Beate, Becker-Ziaja, Carola, Busch, Stephan, Günther   +5 more
openaire   +2 more sources

Bayesian estimation of Lassa virus epidemiological parameters: Implications for spillover prevention using wildlife vaccination.

PLoS Neglected Tropical Diseases, 2020
Lassa virus is a significant burden on human health throughout its endemic region in West Africa, with most human infections the result of spillover from the primary rodent reservoir of the virus, the natal multimammate mouse, M. natalensis.
Scott L Nuismer, Christopher H Remien, Andrew J Basinski, Tanner Varrelman, Nathan Layman, Kyle Rosenke, Brian Bird, Michael Jarvis, Peter Barry, Patrick W Hanley, Elisabeth Fichet-Calvet   +10 more
doaj   +1 more source

Wearable Electronic Monitoring of Vital Signs in Hospitalised Adults: A Nursing Focused Scoping Review of Clinical, Economic and Implementation Outcomes

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To synthesise evidence on wearable devices for continuous vital signs monitoring in adult hospital inpatients, focusing on clinical effectiveness, nursing perspectives, workflow impact, patient experience and resource implications. Design Scoping review.
Sian Myfanwy Shaw, Sophie Bethan Shaw, Gillian Janes   +2 more
wiley   +1 more source

Research Direction and Science Evaluation: The Role of Coherence and Alignment

Journal of Economics &Management Strategy, EarlyView.
ABSTRACT The decisions of funding agencies greatly influence the direction of scientific research; however, our understanding of how applicants' research directions affect the selection process remains limited. In this study, we investigate how a project's coherence with a scientist's previous work and its alignment with current scientific trends ...
Charles Ayoubi, Sandra Barbosu, Michele Pezzoni, Fabiana Visentin   +3 more
wiley   +1 more source