WikiJournal of Medicine, 2019 Lassa fever is a viral hemorrhagic fever caused by Lassa virus (Lassa mammarenavirus), a negative-sense single-stranded RNA virus of the Arenaviridae family. In most cases Lassa virus infection is asymptomatic (presenting no symptom). When symptomatic it
Abdulmutalab Musa
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New Hosts of The Lassa Virus [PDF]
Scientific Reports, 2016 Abstract Lassa virus (LASV) causes a deadly haemorrhagic fever in humans, killing several thousand people in West Africa annually. For 40 years, the Natal multimammate rat, Mastomys natalensis , has been assumed to be the sole host of LASV.
Olayemi, Ayodeji +19 more
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Structural and functional studies of novel mechanisms of Lassa fever virus nucleoprotein in immune suppression, viral RNA transcription and replication [PDF]
, 2013 Lassa fever virus is one of the most dangerous viruses of arenaviridae family, causing more than 500,000 infections per year in Africa. The fatality rate for hospitalized patients is as high as 20%.
Qi, Xiaoxuan
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Use of Favipiravir to Treat Lassa Virus Infection in Macaques
Emerging Infectious Diseases, 2018 Lassa virus, the cause of Lassa fever in humans, is endemic to West Africa. Treatment of Lassa fever is primarily supportive, although ribavirin has shown limited efficacy if administered early during infection.
Kyle Rosenke +12 more
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Development of a new vaccine for the prevention of Lassa fever.
PLoS Medicine, 2005 BACKGROUND: Recent importation of Lassa fever into Germany, the Netherlands, the United Kingdom, and the United States by travelers on commercial airlines from Africa underscores the public health challenge of emerging viruses.
Thomas W Geisbert +15 more
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Nigerian Journal of Paediatrics, 2021 Background: Lassa virus disease (LVD) is of public health concern in endemic countries of Africa. Majority of Lassa virus infections are asymptomatic while symptomatic cases can mimic other infections.
Orji Chito Maria-Lauretta +2 more
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Development and evaluation of antibody-capture immunoassays for detection of Lassa virus nucleoprotein-specific immunoglobulin M and G. [PDF]
PLoS Neglected Tropical Diseases, 2018 The classical method for detection of Lassa virus-specific antibodies is the immunofluorescence assay (IFA) using virus-infected cells as antigen.
Martin Gabriel +23 more
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A GIS-BASED APPROACH TO RISK MAPPING OF LASSA FEVER OUTBREAK IN AKURE SOUTH LOCAL GOVERNMENT AREA, NIGERIA [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2022 Lassa fever is an acute viral illness, which is endemic in some counties in West Africa, including Guinea, Liberia, Sierra Leone and parts of Nigeria.
O. J. Ifejube +3 more
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Prevalence and risk factors of Lassa seropositivity in inhabitants of the forest region of Guinea: a cross-sectional study. [PDF]
, 2009 BACKGROUND: Lassa fever is a viral hemorrhagic fever endemic in West Africa. The reservoir host of the virus is a multimammate rat, Mastomys natalensis.
Fichet-Calvet, Elisabeth +30 more
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Molecular confirmation and phylogeny of Lassa fever virus in Benin Republic 2014–2016
African Journal of Laboratory Medicine, 2019 Background: The changing epidemiology of the Lassa virus from endemic areas to other parts of West Africa has been reported. However, there have been no documented Lassa fever transmission chains in the Benin Republic.
Olumuyiwa B. Salu +7 more
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