Results 11 to 20 of about 17,001 (224)

Survival of Lassa Virus in Blood and Tissue Culture Media and in a Small Particle Aerosol

Pathogens, 2020
Knowledge of the survival and stability of a pathogen is important for understanding its risk, reducing its transmission, and establishing control measures.
Sophie J Smither, Lin S Eastaugh, James S Findlay, Lyn M O’Brien, Mark S Lever   +4 more
doaj   +1 more source

The risk of transmission of a viral haemorrhagic fever infection in a United Kingdom laboratory [PDF]

, 2017
No abstract ...
Shorten, Robert J., Wilson-Davies, Eleri
core   +7 more sources

Predicting the evolution of the Lassa virus endemic area and population at risk over the next decades

Nature Communications, 2022
It is currently unknown how climate and land use changes could affect the endemic area of Lassa virus, a zoonotic pathogen responsible for Lassa fever.
Raphaëlle Klitting, Liana E. Kafetzopoulou, Wim Thiery, Gytis Dudas, Sophie Gryseels, Anjali Kotamarthi, Bram Vrancken, Karthik Gangavarapu, Mambu Momoh, John Demby Sandi, Augustine Goba, Foday Alhasan, Donald S. Grant, Sylvanus Okogbenin, Ephraim Ogbaini-Emovo, Robert F. Garry, Allison R. Smither, Mark Zeller, Matthias G. Pauthner, Michelle McGraw, Laura D. Hughes, Sophie Duraffour, Stephan Günther, Marc A. Suchard, Philippe Lemey, Kristian G. Andersen, Simon Dellicour   +26 more
doaj   +1 more source

Lethal Infection of Lassa Virus Isolated from a Human Clinical Sample in Outbred Guinea Pigs without Adaptation

mSphere, 2019
Lassa virus (LASV), a member of the family Arenaviridae, is the causative agent of Lassa fever. Lassa virus is endemic in West African countries, such as Nigeria, Guinea, Liberia, and Sierra Leone, and causes outbreaks annually.
Junki Maruyama, John T. Manning, Elizabeth J. Mateer, Rachel Sattler, Natalya Bukreyeva, Cheng Huang, Slobodan Paessler   +6 more
doaj   +1 more source

Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay. [PDF]

, 2011
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) emerged as the causal agent of an endemic atypical pneumonia, infecting thousands of people worldwide.
Agudelo, Juliet, Amberg, Sean M, Chen, Yen Ting, Craik, Charles S, Goetz, David H, Hansell, Elizabeth, Lu, Kai, McKerrow, James, Roush, William R, Simmons, Graham, Zhou, Yanchen   +10 more
core   +1 more source

The origin and prevention of pandemics. [PDF]

, 2010
Despite the fact that most emerging diseases stem from the transmission of pathogenic agents from animals to humans, the factors that mediate this process are still ill defined.
Djoko, Cyrille F, Fair, Joseph N, Lebreton, Matthew, Pike, Brian L, Rimoin, Anne W, Saylors, Karen E, Tamoufe, Ubald, Wolfe, Nathan D   +7 more
core   +1 more source

Phylogenetic and Mutational Analysis of Lassa Virus Strains Isolated in Nigeria: Proposal for an In Silico Study

JMIR Research Protocols, 2021
BackgroundIn 2018, the total number of Lassa fever cases in Nigeria was significantly higher than that observed in previous years. Hence, studies had attempted to determine the underlying cause. However, reports using phylogenetic methods to analyze this
Kolawole, Daniel, Raji, Hayatu, Okeke, Malachy Ifeanyi   +2 more
doaj   +1 more source

Comparative structural and functional analysis of Bunyavirus and Arenavirus cap-snatching Endonucleases [PDF]

, 2016
Segmented negative strand RNA viruses of the arena-, bunya- and orthomyxovirus families uniquely carry out viral mRNA transcription by the cap-snatching mechanism.
A Dias, A Perrakis, A Pflug, B Morin, C Klemm, D Duijsings, D Garcin, D Guilligay, E Kowalinski, E Krissinel, E Lecompte, E Thierry, Francesca Coscia, Félix A. Rey, G Sutter, GD Wallat, GN Murshudov, H Hasegawa, H Jin, J Ortin, J Reguera, J Tomassini, JC Clegg, Juan Reguera, M Hass, M Hass, M Lelke, M Zeier, Maria Rosenthal, N Dimasi, N Hengrung, P Gerlach, Piotr Gerlach, R Rosenberg, RM Elliott, RW Compans, S Devignot, S Reich, SJ Plotch, SR Ness, Stephan Günther, Stephanie Gaudon, Stephen Cusack, T Crepin, UB Ericsson, UJ Buchholz, W Kabsch, Y Fernández-García   +47 more
core   +3 more sources

Replicon System for Lassa Virus [PDF]

Journal of Virology, 2004
ABSTRACT Lassa virus is endemic to West Africa and causes hemorrhagic fever in humans. To facilitate the functional analysis of this virus, a replicon system was developed based on Lassa virus strain AV. Genomic and antigenomic minigenomes (MG) were constructed consisting of the intergenic region of S RNA and a reporter gene (
Meike, Hass, Uta, Gölnitz, Stefanie, Müller, Beate, Becker-Ziaja, Stephan, Günther   +4 more
openaire   +2 more sources

Characterization of Lassa Virus Cell Entry and Neutralization with Lassa Virus Pseudoparticles [PDF]

Journal of Virology, 2009
ABSTRACT The cell entry and humoral immune response of the human pathogen Lassa virus (LV), a biosafety level 4 (BSL4) Old World arenavirus, are not well characterized. LV pseudoparticles (LVpp) are a surrogate model system that has been used to decipher factors and routes involved in LV cell entry under BSL2 conditions.
François-Loïc, Cosset, Marianneau, Philippe, Verney, Geraldine, Gallais, Fabrice, Tordo, Noel, Pécheur, Eve-Isabelle, ter Meulen, Jan, Deubel, Vincent, Bartosch, Birke   +8 more
openaire   +4 more sources