Results 61 to 70 of about 1,759,457 (222)

Adaptive Latency Insensitive Protocols [PDF]

, 2007
Latency-insensitive design copes with excessive delays typical of global wires in current and future IC technologies. It achieves its goal via encapsulation of synchronous logic blocks in wrappers that communicate through a latency-insensitive protocol ...
Casu, Mario Roberto, Macchiarulo, Luca
core   +1 more source

Nitride MXenes Beyond Carbides: Bridging the Gap Between Computational Prediction and Experimental Realization

Advanced Functional Materials, EarlyView.
Nitride MXenes remain constrained by a persistent gap between computational prediction and experimental realization. This Review identifies the thermodynamic, kinetic, and chemical barriers limiting their synthesis, critically evaluates emerging fabrication routes, and proposes a multidimensional computational‐experimental framework to accelerate the ...
Naresh Varnakavi, Masoud Soroush
wiley   +1 more source

Global Dynamics of the HIV Latent Reservoir with Latency Reversing Agents and Immune Response

, 2020
In this project, we model the dynamics of HIV-1 latently infected cells under the effects of latency reversing agents (LRAs) to promote a natural immune response. We establish the existence of immune-free and positive equilibria and then utilize Lyapunov
Berchtold, Claire, Mitchum, Hannah
core   +1 more source

Ethnobotanical survey and phytochemistry of medicinal plants used in the management of HIV/AIDS in Eastern Uganda

Heliyon
Currently, highly active antiretroviral therapy is unable to cure HIV/AIDS because of HIV latency. This study aimed at documenting medicinal plants used in the management of HIV/AIDS in Eastern Uganda so as to identify phytochemicals with HIV latency ...
Richard Oriko Owor, Carol Kawuma, Gauden Nantale, Kenedy Kiyimba, Samuel Baker Obakiro, Simple Ouma, Jalia Lulenzi, Yahaya Gavamukulya, Mercy Chebijira, Tonny Wotoyitide Lukwago, Moses Egor, Peter Musagala, Moses Andima, Dan Kibuule, Paul Waako, Joseph Hokello   +15 more
doaj   +1 more source

LEAD: Literature Enhanced Ab Initio Discovery of Nitride Dusting Layers for Enhanced Tunnel Magnetoresistance and Lower Resistance Magnetic Tunnel Junctions

Advanced Materials, EarlyView.
Magnetic tunnel junctions (MTJs) using MgO tunnel barriers face challenges of high resistance‐area product and low tunnel magnetoresistance (TMR). To discover alternative materials, Literature Enhanced Ab initio Discovery (LEAD) is developed. The LEAD‐predicted materials are theoretically evaluated, showing that MTJs with dusting of ScN or TiN on ...
Sabiq Islam, William S. Rogers, Chen‐Yu Hu, Ming‐Yuan Song, Xinyu Bao, Shehrin Sayed, Jean Anne C. Incorvia   +6 more
wiley   +1 more source

Neuromorphic Electronics for Intelligence Everywhere: Emerging Devices, Flexible Platforms, and Scalable System Architectures

Advanced Materials, EarlyView.
The perspective presents an integrated view of neuromorphic technologies, from device physics to real‐time applicability, while highlighting the necessity of full‐stack co‐optimization. By outlining practical hardware‐level strategies to exploit device behavior and mitigate non‐idealities, it shows pathways for building efficient, scalable, and ...
Kapil Bhardwaj, Roshni Satheesh Babu, Yuxin Xia, Eva Bestelink, Radu Sporea, Nikos Hastas, Ioannis Zeimpekis, Dimitra G. Georgiadou, Sayani Majumdar   +8 more
wiley   +1 more source

Total Syntheses of Phorbol and 11 Tigliane Diterpenoids and Their Evaluation as HIV Latency-Reversing Agents

Tigliane diterpenoids possess exceptionally complex structures comprising common 5/7/6/3-membered ABCD-rings and disparate oxygen functionalities.
Masanori Nagatomo (1696051), Satoshi Miura (2667748), Yuto Hikone (11972034), Masayuki Inoue (737292), Akira Hirose (480633), Naoki Kishimoto (82096), Tae Yasutake (18159149), Ayumu Watanabe (11198938), Towa Abe (9369889), Shogo Misumi (2289145)   +9 more
core   +1 more source

Temporal transcriptional response to latency reversing agents identifies specific factors regulating HIV-1 viral transcriptional switch [PDF]

, 2015
Background\ud Latent HIV-1 reservoirs are identified as one of the major challenges to achieve HIV-1 cure. Currently available strategies are associated with wide variability in outcomes both in patients and CD4+ T cell models.
Jain, Siddhartha, Ziv Bar-Joseph, Allison E. Mancini, Sluis-Cremer, Nicolas, Nicolas Sluis-Cremer, Zerbato, Jennifer M., Bar-Joseph, Ziv, Mancini, AE, Venkatachari, Narasimhan J, Velpandi Ayyavoo, Jain, S, Sluis-Cremer, N, Siddhartha Jain, Chattopadhyay, A, Zerbato, JM, Narasimhan J. Venkatachari, Ayyavoo, V, Ansuman Chattopadhyay, Venkatachari, NJ, Jennifer M. Zerbato, Ayyavoo, Velpandi, Mancini, Allison E., Chattopadhyay, Ansuman, Bar-Joseph, Z   +23 more
core   +1 more source

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

Chemical-biology approach to delineate the mechanism of action of HIV-1 latency reversing agents [PDF]

, 2017
Prostratin exhibits potent HIV-1 latency reversing activity, yet its molecular mechanism of action has not been defined in detail. Here, we used a novel chemical biology approach which revealed that the protein kinase C-mitogen activated protein kinase ...
Han, Feng
core