Results 41 to 50 of about 340,687 (262)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Sodium butyrate impedes the lymphoma caused by Marek’s disease virus via regulating the mitochondrial apoptosis pathway

open access: yesFrontiers in Veterinary Science
Sodium butyrate (NaB) has garnered attention in recent years for its ability to impede the malignant progression of tumors. In order to explore the potential inhibitory effects of NaB on the replication of Marek’s disease virus (MDV) and subsequent ...
Qiaoer Lin   +14 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The Potrayal of Hyperreality in Movie Latency (2024)

open access: yesLingual
This research analyzes the construction of hyperreality in the film Latency (2024) through a descriptive qualitative approach by focusing on Baudrillard's (1981) four stages of simulacra.
Arfian Dwi Saputra, Andri Fernanda
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Dynamic Load Balancing for Enhanced Network Performance in IoT-Enabled Smart Healthcare With Fog Computing

open access: yesIEEE Access
The rapid expansion of Internet of Things (IoT) devices in healthcare has increased data volumes, creating challenges for the efficiency and latency of real-time monitoring systems.
Mohammed Alaa Ala'anzy   +4 more
doaj   +1 more source

Bioactive molecules released from cells infected with the Human Cytomegalovirus

open access: yesFrontiers in Microbiology, 2016
Following primary infection in humans, the Human Cytomegalovirus (HCMV) persists in a latent state throughout the host’s lifetime despite a strong and efficient immune response.
Anna eLuganini   +2 more
doaj   +1 more source

Low latency communications [PDF]

open access: yes2013 Information Theory and Applications Workshop (ITA), 2013
Numerous applications demand communication schemes that minimize the transmission delay while achieving a given level of reliability. An extreme case is high-frequency trading whereby saving a fraction of millisecond over a route between Chicago and New York can be a game-changer.
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Identification of Genetically Intact HIV-1 Proviruses in Specific CD4+ T Cells from Effectively Treated Participants

open access: yesCell Reports, 2017
Latent replication-competent HIV-1 persists in individuals on long-term antiretroviral therapy (ART). We developed the Full-Length Individual Proviral Sequencing (FLIPS) assay to determine the distribution of latent replication-competent HIV-1 within ...
Bonnie Hiener   +18 more
doaj   +1 more source

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