Results 41 to 50 of about 570,061 (302)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Control of herpes simplex virus type 1 latency in human trigeminal ganglia [PDF]
, 2012 Herpes simplex virus type 1 (HSV-1) is a double-stranded DNA virus that infects humans and, after a primary lytic infection, establishes lifelong latency in the sensory neurons of the trigeminal ganglia (TG).
Held, Kathrin, Held, K.
core +1 more source
DiagnosticsBackground: The diagnosis of multiple sclerosis (MS) relies on identifying neurological signs and symptoms, supported by evidence of central nervous system (CNS) dissemination of lesions across time and space.
Manuela Andreea Ciapă +3 more
doaj +1 more source
Frontiers in Sustainable Cities, 2022 Irregular heartbeats are a primary indicator of Cardiovascular Disease (CVD), which is the leading cause of death in a developing smart city environment.
C. Prajitha, K. P. Sridhar, S. Baskar
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Latency-Aware Optical Metro Network.MOV
, 2021 This video shows a demonstration of automated deployment of a video surveillance service across a latency-aware, semi-disaggregated, and virtualized metro network. It covers an on-site presentation of the data plane setup and the surveillance zone of the
Behnam Shariati (11188812)
core +1 more source
Frontiers in Veterinary ScienceSodium butyrate (NaB) has garnered attention in recent years for its ability to impede the malignant progression of tumors. In order to explore the potential inhibitory effects of NaB on the replication of Marek’s disease virus (MDV) and subsequent ...
Qiaoer Lin +14 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The Potrayal of Hyperreality in Movie Latency (2024)
LingualThis research analyzes the construction of hyperreality in the film Latency (2024) through a descriptive qualitative approach by focusing on Baudrillard's (1981) four stages of simulacra.
Arfian Dwi Saputra, Andri Fernanda
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source