Results 41 to 50 of about 339,041 (260)

Сучасний стан організованої злочинності в Україні

open access: yesПроблеми Законності, 2016
Статтю присвячено аналізу стану організованої злочинності в Україні за період 2006–2015 рр. Установлено сталу тенденцію  до зменшення основних кількісно-якісних показників, що характеризують діяльність стійких злочинних об’єднань.
Olena Shostko
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

BK polyomavirus: latency, reactivation, diseases and tumorigenesis

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The identification of the first human polyomavirus BK (BKV) has been over half century, The previous epidemiological and phylogenetic studies suggest that BKV prevailed and co-evolved with humans, leading to high seroprevalence all over the world.
Xianfeng Zhou   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Performance Analysis and Enhancements for In-Band Full-Duplex Wireless Local Area Networks

open access: yesIEEE Access, 2020
In-Band Full-Duplex (IBFD) is a technique that enables a wireless node to simultaneously transmit a signal and receive another on the same frequency band.
Murad Murad, Ahmed M. Eltawil
doaj   +1 more source

Energy-Efficient AP Selection Using Intelligent Access Point System to Increase the Lifespan of IoT Devices

open access: yesSensors, 2023
With the emergence of various Internet of Things (IoT) technologies, energy-saving schemes for IoT devices have been rapidly developed. To enhance the energy efficiency of IoT devices in crowded environments with multiple overlapping cells, the selection
Seungjin Lee   +3 more
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Impact of Arm Length and Body Mass Index on Abductor Pollicis Brevis (APB) H-Reflex among Females [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2019
Introduction: Hoffmann reflex (H-reflex) is an electrically induced reflex analogous to the mechanically induced spinal stretch reflex. H-reflex is useful clinically to diagnose nerve root lesions, particularly involving S1 radiculopathy and in proximal ...
D Rekha, B Suganthi
doaj   +1 more source

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