Results 51 to 60 of about 114,379,182 (224)

High Levels of Education Are Associated With an Increased Risk of Latent Autoimmune Diabetes in Adults

, 2010
OBJECTIVE To investigate whether the risk for autoimmune diabetes in adults differs between socioeconomic groups and to compare such risk with that for type 2 diabetes.
Lisa Olsson, Anders Ahlbom, Valdemar Grill, Ahlbom, A,, Kristian Midthjell, Olsson, L,, Midthjell, K, Carlsson, S,, Grill, V, Sofia Carlsson   +9 more
core   +1 more source

Frequency of islet autoantibody seropositivity among adults with newly diagnosed type 2 diabetes in the Kazakh population: A cross‐sectional study

Journal of Diabetes Investigation
Aims/Introduction Type 2 diabetes mellitus (T2DM) is a heterogeneous condition, and a proportion of patients show autoimmune features consistent with latent autoimmune diabetes in adults (LADA).
Khatimya Kudabayeva, Bibigul Tleumagambetova, Yerlan Bazargaliyev, Lorina Vudu   +3 more
doaj   +1 more source

Latent autoimmune diabetes in adults phenotype with recurrent hypoglycemia as diagnostic challenge (case report)

Mìžnarodnij Endokrinologìčnij Žurnal
Latent autoimmune diabetes in adults (LADA) represents a hybrid form of diabetes characterized by autoimmune destruction of β-cells, clinical features of type 2 diabetes, and a slow progression to insulin dependence.
Teuta Mulla Goga, Afrim Zeqiraj
doaj   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

Prevalence and Correlates of Latent Autoimmune Diabetes in Adults in Tianjin, China

, 2010
OBJECTIVE Data on latent autoimmune diabetes in adults (LADA) from population-based studies are sparse. We sought to investigate the prevalence and correlates of LADA.
Yun Xie, Qi, X, Jia, J, Jing Sun, Xie, Y, Wang, J, Jianhua Wang, Zhongliang Xu, Xiuying Qi, Peizhong Peter Wang, Wang, PP, Xie, Yun, Wang, Jianhua, Xu, Z, Xu, Zhongliang, Murphy, Madonna, Jia, Junting, Junting Jia, Xu, W,, Jing Wang, Wang, Jing, Wang, Peizhong Peter, Weili Xu, Sun, J, Madonna Murphy, Xu, Weili,, Murphy, M, Sun, Jing, Qi, Xiuying   +28 more
core   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Latent Autoimmune Diabetes in Adults Differs Genetically From Classical Type 1 Diabetes Diagnosed After the Age of 35 Years

, 2010
OBJECTIVE- We studied differences between patients with latent autoimmune diabetes in adults (LADA), type 2 diabetes, and classical type 1 diabetes diagnosed after age 35 years.
Turunen, Joni A., Lundgren, Virve, Per-Henrik Groop, Isomaa, Bo, Virve Lundgren, Forsblom, Carol, Leif Groop, Groop, Leif, Andersen, Mette K., Groop, Per-Henrik, Groop, Per Henrik, Carol Forsblom, Tiinamaija Tuomi, Bo Isomaa, Mette K. Andersen, Joni A. Turunen, Tuomi, Tiinamaija   +16 more
core   +1 more source

Exogenous Insulin Injection-Induced Stiff-Person Syndrome in a Patient With Latent Autoimmune Diabetes: A Case Report and Literature Review

Frontiers in Endocrinology, 2020
Stiff-person syndrome (SPS) is highly associated with anti-glutamic acid decarboxylase (GAD) antibody. However, GAD antibodies alone appear to be insufficient to cause SPS, and they possibly are involved in only part of its pathophysiology.
Yi-Yin Lee, Cheng-Wei Lin, I-Wen Chen
doaj   +1 more source

GAD65 Antibody Epitopes and Genetic Background in Latent Autoimmune Diabetes in Youth (LADY)

Frontiers in Immunology, 2022
Epitope-specific GAD65Abs and HLA-DR-DQ gene assays help improve the value of risk stratification in autoimmune diabetes mellitus and protect islet function.
Yiman Peng, Xia Li, Yufei Xiang, Xiang Yan, Houde Zhou, Xiaohan Tang, Jin Cheng, Xiaohong Niu, Jing Liu, Qiuhe Ji, Linong Ji, Gan Huang, Zhiguang Zhou   +12 more
doaj   +1 more source