Results 141 to 150 of about 106,553 (247)

Review of Herpes Zoster Occurrence in Patients With Atopic Dermatitis Treated With JAK Inhibitors

open access: yesClinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disease that markedly impairs quality of life. Janus kinase inhibitors (upadacitinib, abrocitinib, and baricitinib) are effective therapies for moderate‐to‐severe AD but are associated with viral reactivation, particularly herpes zoster (HZ), due to immunosuppressive effects on interferon ...
Anna Mandecka   +7 more
wiley   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

open access: yesThe FEBS Journal, Volume 293, Issue 6, Page 1587-1611, March 2026.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza   +4 more
wiley   +1 more source

A Case of Palmoplantar Vesiculobullous Lesions

open access: yes
JEADV Clinical Practice, Volume 5, Issue 1, Page 315-318, March 2026.
Ali Abid   +3 more
wiley   +1 more source

The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design

open access: yesJournal of the American Geriatrics Society, Volume 74, Issue 3, Page 636-647, March 2026.
ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui   +11 more
wiley   +1 more source

Latent tuberculosis

open access: yesJournal of the Pediatrics Association of India, 2014
VN Kamale, Sawant Sandeep, NC Mohanty
openaire   +1 more source

Cytotoxicity and Antimicrobial Activity of GaMF1 Analogs

open access: yesChemMedChem, Volume 21, Issue 4, 25 February 2026.
GaMF1 is a reported, highly potent inhibitor of mycobacterial ATP synthase. Structural modification of this scaffold significantly changes biological activity. We present GaMF1 analogues with strong antiparasitic effects, potential antiproliferative properties, and discuss the selectivity limitations of the parent compound and its analogues.
Jan Chasák   +8 more
wiley   +1 more source

Alterations in the Immune Response in Individuals with Latent Tuberculosis Infection. [PDF]

open access: yesPathogens
Starshinova A   +11 more
europepmc   +1 more source

Which doctor? Combining vignettes and item response to measure doctor quality [PDF]

open access: yes
The authors develop a method in which vignettes-a battery of questions for hypothetical cases-are evaluated with item response theory to create a metric for doctor quality. The method allows a simultaneous estimation of quality and validation of the test
Das, Jishnu, Hammer, Jeffrey
core  

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