Lc-hrms - Open Access .click

Results 91 to 100 of about 21,610 (241)

Role of glutathione and cysteine in acrylamide metabolism during in vitro and in vivo digestion

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Background Acrylamide, a probable human carcinogen found in thermally processed potato products, is reactive towards amino and thiol compounds. This reactivity suggests acrylamide might react with them in the gastrointestinal tract resulting in mitigation of associated risk with acrylamide.
Burçe Ataç Mogol +11 more
wiley +1 more source

Determination of adulteration in hair serums by LC-HRMS §

Journal of Chemical Metrology, 2023
Ahmet C. Gören +3 more
openaire +1 more source

Polymerized Pro‐Estrogen Microneedles via Two Photon Polymerization

Macromolecular Rapid Communications, EarlyView.
Acrylic pro‐drugs of 17β‐estradiol were subjected to spatially controlled two‐photon polymerization to create bespoke microneedle geometries with potential biomedical applications for long‐term transdermal hormone delivery. ABSTRACT Two‐photon polymerization (TPP) is a powerful technique to create microscale structures with high precision, offering ...
Yang Lou +6 more
wiley +1 more source

Combining LC-HRMS and LC-HRMS/MS data to explore a cereal food processed under different conditions

Characterizing the chemical fingerprint of a processed food is a major challenge to advance food quality. New untargeted approaches based on LC-HRMS analysis can unlock the potential to increase our understanding on how chemical components, linked to different food quality dimensions, react and evolve during the manufacturing processes and thus ...
Farah, Soha +5 more
openaire +1 more source

Analytical Approaches to Address Challenges in the Analysis of Cannabinoids in Vascular Matrices Using Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Phytocannabinoids are bioactive metabolites derived from the Cannabis sativa plant. They have garnered attention due to their recreational uses and therapeutic potential. Although various analytical strategies have been employed for their analysis, mass spectrometry (MS) coupled to chromatographic separation is superior due to its sensitivity ...
Radwa Mahmoud, Robert B. Laprairie, Anas El‐Aneed +2 more
wiley +1 more source

Chemical Ionization Mass Spectrometry: Fundamental Principles, Diverse Applications, and the Latest Technological Frontiers

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The review examines the evolution of chemical ionization mass spectrometry (CI‐MS), a technique developed in 1966 by Field and Munson. CI is a soft‐ionization method that produces more intense molecular ions with less fragmentation than electron ionization (EI).
Malvika Dutt +4 more
wiley +1 more source

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

Movement Disorders, EarlyView.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step +680 more
wiley +1 more source

Chemical Compound Profile of Bajakah Kalalawit (Uncaria gambir Roxb) Stem Extract Using Liquid Chromatography High-Resolution Mass Spectrometry

Borneo Journal of Pharmacy
Uncaria gambir Roxb., commonly known as Bajakah Kalalawit, is a plant endemic to Kalimantan, Indonesia, with potential medicinal properties. While previous studies have investigated the phytochemical composition of U.
Ainun Fawaid, Nurkhasanah Mahfudh
doaj +1 more source

High‐Resolution Ion Mobility as an Alternative to Quadrupole‐Based Precursor Isolation for Reducing Chimeric Fragmentation Spectra in Bottom‐Up Proteomics

PROTEOMICS, EarlyView.
ABSTRACT To assess the potential for high resolution ion mobility (HRIM) as an alternative means of precursor isolation for mass spectrometry fragmentation analysis we performed a meta‐analysis of predicted tryptic peptide features from the human proteome to measure the rate of chimeric spectrum generation relative to traditional quadrupole‐based ...
Isabel R. Uribe +5 more
wiley +1 more source

Phospholipid Profiling: A Computationally Assisted LC-HRMS Approach in Lecithin

Separations
The use of lecithin as an emulsifier in food supplements has increased in recent years. However, successful formation of liposomes or micelles requires an appropriate mixture of phospholipids in lecithin.
Ana Šijanec, Matevž Pompe
doaj +1 more source

mass spectrometry
chromatography, liquid
metabolomics

humans
3. good health
tandem mass spectrometry

chromatography, high pressure liquid
high-resolution mass spectrometry
metabolites