Results 261 to 270 of about 100,610 (290)

Calcium overload induced mitochondrial and lysosomal dysfunction is regulated by Tousled-like kinase in a-synucleinopathy. [PDF]

Cell Death Dis
Gong F, Cheng Q.
europepmc   +1 more source

Thrombospondin 1 aggravates cardiac remodeling in heart failure with preserved ejection fraction by inhibiting mitophagy. [PDF]

iScience
Bu X, Sha S, Zhang Z, Bian S, Feng S, Li C, Wang L, Chen H.   +7 more
europepmc   +1 more source

The oncolytic avian reovirus p17 protein triggers chaperone-mediated autophagy by modulating Hsp90 and the T-complex protein-1 ring complex chaperones and co-chaperones to activate the IKK/NF-κB signaling. [PDF]

J Virol
Huang W, Li J-Y, Liao T-L, Lye L-F, Munir M, Liu H-J.   +5 more
europepmc   +1 more source

HBHA-ECSIT interaction disrupts macrophage autophagy to promote Mycobacterium tuberculosis persistence. [PDF]

Front Immunol
Li Y, Jia X, Wang X, Qiao H, Ma Y.
europepmc   +1 more source

Singapore grouper iridovirus utilizes Rab1 to facilitate viral trafficking and evade the immune response by targeting the STING-IRF3 pathway. [PDF]

Cell Commun Signal
Guan L, Zhang X, Xu Z, Li Y, Zhang L, Wang H, Zhang Z, Wei X, Liu Y, Qin Q, Wang S.   +10 more
europepmc   +1 more source

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Monitoring Autophagy with GFP-LC3 Reporter

2023
Autophagy is a key process that maintains cellular homeostasis. Autophagy contributes to various physiological and pathophysiological processes. Development of methodologies for autophagy detection has greatly facilitated the research on autophagy. Among these methodologies, GFP-LC3 reporter has been popularly used in the literature.
Lidong, Sun, Suli, Lv, Tanjing, Song
openaire   +2 more sources

Live cell imaging of LC3 dynamics

2021
Macroautophagy (hereafter referred to as autophagy) serves the liberation of energy resources through the degradation of cellular components and is characterized by the formation of double-membraned vesicles, commonly referred to as autophagosomes. Microtubule-associated proteins 1A/1B light chain 3B (hereafter referred to as LC3) plays a crucial role ...
Giulia, Cerrato, Allan, Sauvat, Oliver, Kepp, Guido, Kroemer   +3 more
openaire   +2 more sources

How to Interpret LC3 Immunoblotting

Autophagy, 2007
Microtubule-associated protein light chain 3 (LC3) is now widely used to monitor autophagy. One approach is to detect LC3 conversion (LC3-I to LC3-II) by immunoblot analysis because the amount of LC3-II is clearly correlated with the number of autophagosomes.
Noboru, Mizushima, Tamotsu, Yoshimori
openaire   +2 more sources