ACTB, CDKN1B, GAPDH, GRB2, RHOA and SDCBP Were Identified as Reference Genes in Neuroendocrine Lung Cancer via the nCounter Technology [PDF]
, 2016 Background Neuroendocrine lung cancer (NELC) represents 25% of all lung cancer cases and large patient collectives exist as formalin-fixed, paraffin-embedded (FFPE) tissue only.
Christoph, Daniel Christian +5 more
core +1 more source
Race, insurance type, and stage of presentation among lung cancer patients [PDF]
, 2014 The purpose of this study was to determine whether African-American lung cancer patients are diagnosed at a later stage than white patients, regardless of insurance type. The relationship between race and stage at diagnosis by insurance type was assessed
Biswas, Tithi +7 more
core +2 more sources
Molecular Subtypes of Extra-pulmonary Neuroendocrine Carcinomas Identified by the Expression of Neuroendocrine Lineage-Specific Transcription Factors [PDF]
, 2022 Extra-pulmonary neuroendocrine carcinomas (EPNEC) represent a group of rare and heterogenous neoplasms with adverse clinical outcome. Their molecular profile is largely unexplored.
Birocco, Nadia +10 more
core +1 more source
Pure Large Cell Neuroendocrine Carcinoma of the Ovary with Metastasis to Cervix: A Rare Case Report and Review of Literature [PDF]
Journal of Clinical and Diagnostic Research, 2016 Ovarian Large Cell Neuroendocrine Carcinoma (LCNEC) is a recently described rare entity, which even more rarely occurs in a ‘pure’ form without any associated surface epithelial-stromal or germ cell component.
Lakshmi Agarwal +2 more
doaj +1 more source
Somatostatin receptor PET/CT in restaging of typical and atypical lung carcinoids [PDF]
, 2015 Background To assess the role of somatostatin receptor (SR) PET/CT using Ga-68 DOTATOC or DOTATATE in staging and restaging of typical (TC) and atypical (AC) lung carcinoids.
Apostolopoulou, Konstantina +8 more
core +2 more sources
Scientific Reports, 2022 The optimal systemic treatment of advanced large cell neuroendocrine carcinoma (LCNEC) is still controversial. We intend to explore advanced LCNEC through SEER database, construct nomogram model of advanced LCNEC, and understand the effect of different ...
Lu Xia +3 more
doaj +1 more source
PD-L1 testing for lung cancer in the UK: recognizing the challenges for implementation. [PDF]
, 2016 A new approach to the management of non-small-cell lung cancer (NSCLC) has recently emerged that works by manipulating the immune checkpoint controlled by programmed death receptor 1 (PD-1) and its ligand programmed death ligand 1 (PD-L1).
Booton, R +11 more
core +2 more sources
Neuroendocrine neoplasms of the lung: a pathology update [PDF]
, 2021 Purpose: Neuroendocrine tumors and neuroendocrine carcinomas in the lung are distinct and separate entities featuring neuroendocrine differentiation, for which an accurate classification is clinically warranted.
Barella M., Metovic J., Pelosi G.
core +1 more source
Large cell neuroendocrine carcinoma with a solitary brain metastasis and low Ki-67: a unique subtype
Endocrine Connections, 2019 Introduction: Stage IV large cell neuroendocrine carcinoma (LCNEC) of the lung generally presents as disseminated and aggressive disease with a Ki-67 proliferation index (PI) 40–80%.
B C M Hermans +8 more
doaj +1 more source
Combined Adenosquamous and Large Cell Neuroendocrine Carcinoma of the Gallbladder [PDF]
Journal of Pathology and Translational Medicine, 2018 Large cell neuroendocrine carcinoma (LCNEC) of the gallbladder is extremely rare and usually combined with other type of malignancy, mostly adenocarcinoma. We report an unusual case of combined adenosquamous carcinoma and LCNEC of the gallbladder in a 54-
Jiyoon Jung +7 more
doaj +1 more source