Results 111 to 120 of about 44,701 (203)

Insecticidal Activity of Trichilia hirta L. (Sapindales: Meliaceae) Extracts Against Spodoptera frugiperda (Lepidoptera: Noctuidae) Larvae and the Identification of Bioactive Compounds

open access: yesChemistry &Biodiversity, Volume 23, Issue 3, March 2026.
Fruits of Trichilia hirta were extracted and fractionated according to solvent polarity. The resulting partitions were screened for insecticidal activity by evaluating larval mortality and weight after 7 and 14 days. LC‐MS analysis of the most active fraction enabled the annotation of secondary metabolites potentially associated with the observed ...
Mayara Barreto de Souza Arantes   +13 more
wiley   +1 more source

Isolation, RP‐UHPLC‐ESI‐LIT‐Orbitrap‐MS/MS‐Based Metabolic Profiling and Anticandidal Activity of the Root and Leaf Secondary Metabolites of Monotes Kerstingii Gilg (Dipterocarpaceae)

open access: yesChemistry &Biodiversity, Volume 23, Issue 3, March 2026.
This paper describes the isolation and antifungal activity of secondary metabolites from the leaves and roots of Monotes kerstingii. The distribution of these metabolites in the roots and leaves was achieved through comprehensive RP‐UHPLC‐Orbitrap‐MS and MS/MS analysis.
Sorelle Kache Fotsing   +12 more
wiley   +1 more source

Antidiabetic Potential of Ligands from NEIST_PMIB_06, Bacterium Associated With Hawaijar (Fermented Soy Food): Insight from in Vitro and in Silico Studies

open access: yesChemFoodChem, Volume 2, Issue 1, March 2026.
ABSTRACT In this study, a bacterium (NEIST_PMIB_06) was isolated from Hawaijar, a fermented soy food from Manipur, Northeast India. The bacterium was inoculated and incubated to isolate bioactive compounds. Liquid‐liquid extraction was performed to obtain extracts (cell‐free and cell‐based), and their efficacy was evaluated.
A Ibeyaima   +2 more
wiley   +1 more source

Elucidating Trigonelline's Therapeutic Mechanisms for Traumatic Brain Injury Through Integrated Network Pharmacology and In Vivo Validation

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
Trigonelline alleviates traumatic brain injury (TBI) by attenuating oxidative stress and neuroinflammation. It inhibits MAPK signaling–mediated neuronal apoptosis and reduces cerebral edema via downregulation of AQP4 and MMP‐9, thereby maintaining blood–brain barrier integrity.
Qian Zhang   +7 more
wiley   +1 more source

Recent Insights on Synthesis, Stability, and Complexities of Water‐in‐Oil Pickering Emulsion: From Theory to Applications

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
It provides a conceeptual framework of the core components required for w/o PE development and various internal and external factors determining the emulsion stabilization. It also emphasizes the emerging application of w/o PE in diverse industrial use such as encapsulation and delivery, packaging, food, biomedical, etc.
Bibha Mishra A., Vidisha Tomer
wiley   +1 more source

Carissa carandas L. and Its Methanol Extracts Promote Hematopoiesis and Thrombocytopoiesis: A Sub‐Acute Toxicological Study in Experimental Rats

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
Carissa carandas powder and extracts improve hematological indices, for example, hemoglobin and hematocrits. Supplementation of C. carandas significantly enhances thrombocytopoiesis and platelets. Incorporation of Carissa carandas exhibited no toxic effects on liver and kidney histology. ABSTRACT Carissa carandas—a member of the family Apocynaceae, has
Wisha Saeed   +10 more
wiley   +1 more source

QSAR of caffeines by similarity cluster prediction

open access: yesOpen Chemistry, 2014
Harsa Teodora   +2 more
doaj   +1 more source

Leonurine: A Multifaceted Bioactive Alkaloid—From Pharmacological Mechanisms to Clinical Translation: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti‐inflammatory, antiapoptotic, Antitumor, and vasoprotective effects. This review aims to provide a comprehensive overview of LEO's pharmacokinetics, pharmacological mechanisms ...
Zhouyue Gu
wiley   +1 more source

Establishing the Kenya National Antivenom Quality Control Laboratory: Preclinical Efficacy Results of Four Antivenoms Against Venoms from the "Big Five" Snake Species in Kenya. [PDF]

open access: yesToxins (Basel)
Musabyimana V   +15 more
europepmc   +1 more source

Influence of radiotherapy dose rate on gold nanoparticle‐induced radiosensitization from high dose‐rate brachytherapy and external beam therapy

open access: yesMedical Physics, Volume 53, Issue 3, March 2026.
Abstract Background Associated normal tissue toxicity from current radiotherapy (RT) treatments limits effective dose escalation in the tumor to achieve nominal treatment results. Gold nanoparticles (GNPs) as radiosensitizing agents to locally increase photoelectron production have gained interest as a safe and viable method to improve therapeutic ...
Daniel Cecchi   +6 more
wiley   +1 more source

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