Results 61 to 70 of about 93,186 (232)

Estimation of LD50 by moving averages [PDF]

Journal of Hygiene, 1952
Methods of graduation of a series of observations by means of moving averages were discussed by Sheppard (1914), and subsequently by Sherriff (1920) and a number of other writers. These methods based on least squares or weighted least squares solutions differ from actuarial or summation methods.
openaire   +2 more sources

Long-lasting cross-protection against influenza A by neuraminidase and M2e-based immunization strategies [PDF]

, 2016
There is mounting evidence that in the absence of neutralizing antibodies cross-reactive T cells provide protection against pandemic influenza viruses. Here, we compared protection and CD8+ T cell responses following challenge with H1N1 2009 pandemic and
Callewaert, Nico, Fiers, Walter, Saelens, Xavier, Schepens, Bert, Schotsaert, Michael, Smet, Anouk, Stegalkina, Svetlana, Vanderschaeghe, Dieter, Vogel, Thorsten U, Ysenbaert, Tine   +9 more
core   +2 more sources

Antidiabetic Potential of Ligands from NEIST_PMIB_06, Bacterium Associated with Hawaijar (Fermented Soy Food): Insight from in Vitro and in Silico Studies

ChemFoodChem, EarlyView.
ABSTRACT In this study, a bacterium (NEIST_PMIB_06) was isolated from Hawaijar, a fermented soy food from Manipur, Northeast India. The bacterium was inoculated and incubated to isolate bioactive compounds. Liquid‐liquid extraction was performed to obtain extracts (cell‐free and cell‐based), and their efficacy was evaluated.
A Ibeyaima, Hiranmoy Barman, Prasenjit Manna   +2 more
wiley   +1 more source

Uji Toksisitas Akut Dermal Gel Antioksidan Topikal C-4-Hidroksi-3-Metoksifenilkaliks[4] Resorsinarena Secara In Vivo Pada Tikus Wistar

Jurnal Penelitian Pendidikan, Psikologi dan Kesehatan
Pemberian antioksidan topikal merupakan cara yang efektif untuk melindungi kerusakan kulit yang disebabkan oleh sinar ultraviolet. Senyawa C-4-hidroksi-3-metoksifenilkaliks[4]-resorcinarene telah diteliti aktivitas antioksidannya, tabir surya, dan ...
Wade Marlinda, Eti Nurwening Sholikhah, Tri Murini   +2 more
doaj   +1 more source

Acute oral toxicity evaluation of Hridayarnava Rasa (A Herbo-Mineral Ayurvedic Formulation) prepared from aśodhita and śodhita tāmra bhasma

Ancient Science of Life, 2018
Background: Herbo-mineral preparations used in Ayurveda are seen as a matter of concern nowadays; especially for containing metals such as mercury, lead, and copper.
Chandrashekhar Yuvaraj Jagtap, Mukesh Nariya, Vinay J Shukla, Pradeep Kumar Prajapati   +3 more
doaj   +1 more source

Effect of Photobiomodulation on Vinblastine-Poisoned Murine HERS Cells [PDF]

, 2010
Objective: The aim of this study was to investigate the effect of near-infrared (NIR) photobiomodulation on the proliferation and glutathione levels in murine Hertwig\u27s epithelial root sheath (HERS) cells after poisoning with vinblastine.
Buchmann, E., Henry, Michele M, Hodgson, Brian D., Pyszka, B., Whelan, Harry T.   +4 more
core   +1 more source

A comparative study of hydrophilic phosphine hexanuclear rhenium cluster complexes’ toxicity [PDF]

, 2017
Octahedral rhenium cluster compound Na2H8[{Re6Se8}(P(C2H4CONH2)(C2H4COO)2)6] has recently emerged as a very promising X-ray contrast agent for biomedical applications.
Alekseev, Alexander Y., Brylev, Konstantin A., Efremova, Olga A., Gulyaeva, Marina A., Ivanov, Anton A., Krasilnikova, Anna A., Kurskaya, Olga G., Mironov, Yuri V., Poveshchenko, Alexander F., Pozmogova, Tatiana N., Shestopalov, Alexander M., Shestopalov, Michael A., Shestopalova, Lidiya V., Solovieva, Anastasiya O.   +13 more
core   +1 more source

Evaluation of the Therapeutic Potential of Bioactive Materials Based on a Complex of Oxidovanadium(IV) and Exopolysaccharide Levan in a Model of Insulin Resistance in Mice

ChemMedChem, EarlyView.
A low‐toxicity bioactive composition of oxidovanadium(IV) and exopolysaccharide levan is synthesized, characterized, and shown to reduce hyperglycemia, hypertriglyceridemia, and TyG index in a mice model of dexamethasone‐induced insulin resistance. Bioactive compositions containing vanadium complexes have been a viable strategy for constructing more ...
Amanda K. J. P. F. da Silva, Eucilene K. de L. B. Marques, Lidiane M. A. de Lima, Widarlane A. S. Alves, Dayane A. Gomes, Pedro L. Guzzo, Mônica F. Belian, Wagner E. Silva, Eduardo C. Lira   +8 more
wiley   +1 more source

Cellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Disease [PDF]

, 2015
Copyright © 2015, The American Society for Biochemistry and Molecular Biology. Acknowledgements-We thank Drs Timo Rager and Rolf Hilfiker (Solvias, Switzerland) for polymorph analyses.Peer reviewedPublisher ...
Clunas, Scott, Harrington, Charles R, Harrington, Kathleen A, Horsley, David, Ishaq, Ahtsham, Kemp, Steven J, Larch, Christopher P, Marshall, Colin, Nicoll, Sarah L, Rickard, Janet E, Simpson, Michael, Sinclair, James P, Storey, John M D, Storey, Lynda J, Wischik, Claude M   +14 more
core   +1 more source

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

Clinical Pharmacology &Therapeutics, EarlyView.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher, John Mann, Anik Chaturbedi, Shilpa Chakravartula, Hamed Meshkin, Affan Affan, Alexander Galluppi, Ji Young Kim, Nigar Karimli, Yue Han, Zachary Dezman, Jeffry Florian, Zhihua Li   +12 more
wiley   +1 more source