Results 61 to 70 of about 44,701 (203)

Aloe vera in Food Preservation: Harnessing Bioactive Constituents for Clean‐Label Innovation and Safety Assurance

open access: yesFood Safety and Health, EarlyView.
Aloe vera‐derived biopolymers and nanoformulations enhance antimicrobial, antioxidant, and barrier functions in clean‐label edible coatings and films, whereas safety‐critical anthraquinone thresholds and regulatory constraints shape their translational potential.
Acharya Balkrishna   +6 more
wiley   +1 more source

Determination of Median Lethal Dose of Carbamate Insecticides Bendiocarb and Carbaryl in Garden Lizard, Calotes versicolor [PDF]

open access: yesJournal of Stress Physiology & Biochemistry
Acute lethality usually determined as LD50 is defined as median dose predicted to kill 50 percent of a given test population. LD50 is a statistical estimate of the number of milligram of toxicant per kilo gram of body weight administered by any of the ...
Anisha, Tumul Singh
doaj  

Assessment of Gold‐Mediated Male Reproductive Dysfunction in Male WISTAR Rats Through Sperm Analysis and Testosterone Measurement

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Gold has been used for centuries in both ornamental and medicinal contexts. More recently, gold compounds, containing ions or nanoparticles, have attracted attention for their anti‐inflammatory, anticancer, and diagnostic applications. Therefore, concerns about systemic toxicity and biodistribution have prompted investigations into the ...
Samira Maghraoui   +2 more
wiley   +1 more source

ACUTE ORAL AND CUTANEOUS TOXICITIES OF CYFLUNIT- FLOCK TESTED ON LABORATORY ANIMALS

open access: yesРоссийский паразитологический журнал, 2016
Objective of research: to determine the toxicological properties of the preparation Cyflunit- Flock under acute experimental conditions at oral and subcutaneous administration routes to laboratory animals.
E. V. Glukhareva
doaj  

Exploration of the Phytochemical and Antidiabetic Properties of Teucrium polium: A Natural Asset for Type 2 Diabetes Management

open access: yesChemistryOpen, EarlyView.
Teucrium polium shows antidiabetic activity with its phytochemical composition and biological activities. The essential oil is rich in carvacrol, thymol, γ‐terpinene, and o‐cymene, while the aqueous and hydroethanolic extracts are characterized by poliumoside, verbascoside, isorhamnetin‐3‐O‐rutinoside, and apigenin‐7‐rutinoside. Antioxidant activity is
Hajar El Ouadni   +10 more
wiley   +1 more source

Artificial Intelligence Calculation of Median Lethal Dose: A Word of Caution [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology
Traditional toxicity studies rely on laboratory animal experimentations to estimate the median lethal dose (LD50) of chemicals such as pesticides and medications.
Fouad Mohammad
doaj   +1 more source

Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System

open access: yesChemistryOpen, EarlyView.
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz   +10 more
wiley   +1 more source

Computational Study on Potentially Active Antibacterial Compounds in Secondary Metabolites of Extremophilic Microorganisms

open access: yesChemistryOpen, EarlyView.
This study employed density functional theory (DFT) and conceptual DFT (CDFT) to calculate the structures and properties of potential antibacterial compounds derived from 16‐membered lactone ring‐containing secondary metabolites of extremophiles, as well as midecamycin.
Dilong Li   +6 more
wiley   +1 more source

Acute toxicity effects of ethylene glycol on lethal dose 50 (LD50), urine production, and histopathology change renal tubule cell in mice

open access: yesOpen Veterinary Journal
Background: The LD50 (lethal dose causing 50% mortality) of ethylene glycol (EG) and its associated toxicity in mice (Mus musculus) were assessed by evaluating kidney function. Aim: This study aimed to determine the acute toxicity of oral lethal dose
Dewa Ketut Meles   +13 more
doaj   +1 more source

Susceptibility of selected murine and microtine species to infection by a wild strain of Francisella tularensis subsp. holoarctica

open access: yesVeterinární Medicína, 2009
The purpose of this study was to compare susceptibility of BALB/c mice, common voles (Microtus arvalis) and yellow-necked mice (Apodemus flavicollis) to infection by a virulent Francisella tularensis subsp. holarctica strain.
H. Bandouchova   +7 more
doaj   +1 more source

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