ABSTRACT Objective Bariatric surgery has been suggested to improve obstructive sleep apnea (OSA) in short‐term studies, but long‐term evidence is limited. We evaluated remission and new onset of OSA over 20 years in participants from the Swedish Obese Subjects (SOS) study, comparing bariatric surgery with usual obesity care.
Ida Arnetorp +8 more
wiley +1 more source
Extensive LDL-cholesterol lowering by PCSK9 inhibitor on the risk of venous thrombosis. [PDF]
Goto S, Goto S.
europepmc +1 more source
Retatrutide Shows Multiple Metabolic Benefits in Diet‐Induced Obese MASH Mouse and Hamster Models
ABSTRACT Objective/Methods Our aim was to evaluate the efficacy of the triple glucagon, GIP, and GLP‐1 receptor agonist retatrutide in diet‐induced obese MASH mouse and hamster models, two preclinical models that we routinely use for assessing new therapies targeting obesity.
François Briand +6 more
wiley +1 more source
Beyond LDL cholesterol: remnant cholesterol is associated with cardiometabolic risk factors in children. [PDF]
Torres-Costoso A +9 more
europepmc +1 more source
ABSTRACT Objective Glucose tolerance (GT) is a major effector for adipose tissue (AT) remodeling in obesity, yet its molecular mechanisms remain incompletely defined. We hypothesized that the biophysical and molecular profiles of AT‐derived small extracellular vesicles (sEVAT) change in response to glucose availability and differ by GT status.
Shalini Mishra +10 more
wiley +1 more source
LDL cholesterol burden in elderly patients with familial hypercholesterolemia: Insights from real-world data. [PDF]
Melnes T +9 more
europepmc +1 more source
Increased hepatic PAFR expression in MASLD is associated with histological disease severity and may contribute to progression through platelet activation, whereas circulating Lp‐PLA2 levels lack discriminatory value as a noninvasive biomarker. ABSTRACT Objective This study aimed to investigate the platelet‐activating factor (PAF) pathway in obesity ...
Joan Duran‐Bertran +11 more
wiley +1 more source
Impact of fasting duration on LDL cholesterol concentrations estimated by the Friedewald, Martin-Hopkins, and Sampson/NIH equations. [PDF]
Ercan Ş, Manav A.
europepmc +1 more source
Achievement of LDL-Cholesterol Goals in Patients Receiving LLT in Primary Care: TERESA-AP Study: LDL-Cholesterol Goals in Primary Care. [PDF]
Cinza-Sanjurjo S +4 more
europepmc +1 more source
Carbohydrate Restriction-Induced Elevations in LDL-Cholesterol and Atherosclerosis: The KETO Trial. [PDF]
Budoff M +9 more
europepmc +1 more source

