Results 171 to 180 of about 2,591,141 (428)

Isolation of allele-specific, receptor-binding-defective low density lipoproteins from familial defective apolipoprotein B-100 subjects.

Journal of Lipid Research, 1994
Familial defective apolipoprotein B-100 (FDB) is a genetic disorder apparently caused by a single amino acid substitution (Arg3500–>Gln) that disrupts the binding of low density lipoproteins (LDL) to the LDL receptor.
K S Arnold, M E Balestra, R M Krauss, L K Curtiss, S G Young, T L Innerarity   +5 more
doaj  

INtravaScular OptIcal Frequency Domain ImaGing EvaluaTion of the Femoropopliteal Lesion With JETSTREAM Atherectomy (INSIGHT JETSTREAM)

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background There have been no prior reports of detailed evaluations using intravascular imaging during Jetstream treatment. Aims This study, therefore, aimed to investigate the effects of calcification characteristics and wire bias on lumen gain in Jetstream atherectomy using optical frequency domain imaging (OFDI). Methods This study enrolled
Koji Kuroda, Amane Kozuki, Kenzo Uzu, Takafumi Todoroki, Masamichi Iwasaki, Junichi Imanishi, Souichiro Yamashita, Wataru Fujimoto, Makoto Takemoto, Mayuka Masuda, Masanori Okuda   +10 more
wiley   +1 more source

Primary structure comparison of the proposed low density lipoprotein (LDL) receptor binding domain of human and pig apolipoprotein B: implications for LDL-receptor interactions

Journal of Lipid Research, 1988
Apolipoprotein B (apoB) is the predominant protein in low density lipoprotein (LDL) and is responsible for LDL binding to the LDL receptor. Although the primary amino acid sequence of human apoB has been determined, little is known about the structural ...
D L Ebert, N Maeda, S W Lowe, J Hasler-Rapacz, J Rapacz, A D Attie   +5 more
doaj  

Lack of Cross-Reactivity Allergy Following a Switch from Alirocumab to Evolocumab [PDF]

, 2016
The proprotein convertase subtilisin/kexin type 9 (PCSK9) gene and gain-of-function mutations were first described in 2003. The gain-of-function mutations observed were associated with low-density lipoprotein-cholesterol (LDL-C) levels in the 400’s, in ...
Busch, Robert, Kane, Michael, Stryker, Matthew D   +2 more
core   +1 more source

Incidence and 1‐Year Prognostic of Unstable Angina After High‐Sensitivity Troponin Assessment

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Incidence and prognostic of unstable angina after high‐sensitivity troponin assesment is controversial. Aims This study evaluated prognostic of a contemporary population of patients with UA defined using high sensitive T troponin (T hs‐cTn) measurements and with significant coronary artery disease (CAD). Methods Consecutive patients
Romain Jouen, Pierre‐Alain Meunier, Lionel Moulis, Francois Roubille, Jean‐Christophe Macia, Jean‐Michel Berdeu, Matthieu Steinecker, Pierre Robert, Benoit Lattuca, Guillaume Cayla, Florence Leclercq   +10 more
wiley   +1 more source

The protective effects of rutin on the liver, kidneys, and heart by counteracting organ toxicity caused by synthetic and natural compounds

Food Science &Nutrition, Volume 11, Issue 1, Page 39-56, January 2023., 2023
Rutin is a flavonoid present in many plant species. Because of its antioxidant, anti‐inflammatory, and anti‐apoptotic properties, rutin is of interest for its potential protective effects against toxic agents. Rutin has potential therapeutic effectiveness against several toxicants, and its beneficial effects are more than likely mediated by its ...
Sohrab Rahmani, Karim Naraki, Ali Roohbakhsh, A. Wallace Hayes, Gholamreza Karimi   +4 more
wiley   +1 more source

Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism. [PDF]

, 1987
U P Steinbrecher, Joseph L. Witztum, S Parthasarathy, Daniel Steinberg   +3 more
openalex   +1 more source

Impact of Diabetes on Long‐Term Outcomes of Percutaneous Coronary Intervention for Coronary Bifurcation Lesions

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) is a well‐known risk factor for cardiovascular diseases, including coronary artery diseases (CAD). Complex percutaneous coronary intervention (PCI) such as PCI for bifurcation lesions often yields poor outcomes, especially in DM patients.
Subin Lim, Soon Jun Hong, Ju Hyeon Kim, Jung‐Joon Cha, Hyung Joon Joo, Jae Hyoung Park, Cheol Woong Yu, Do‐Sun Lim, Chang‐Wook Nam, the COBIS III investigators, Hyo‐Soo Kim, Woo Jung Chun, Seung‐Ho Hur, Seung Hwan Han, Seung‐Woon Rha, In‐Ho Chae, Jin‐Ok Jeong, Jung Ho Heo, Junghan Yoon, Ki Hong Choi, Young Bin Song, Hyeon‐Cheol Gwon, Jong‐Seon Park, Myeong‐Ki Hong, Joon‐Hyung Doh, Kwang Soo Cha, Doo‐Il Kim, Sang Yeub Lee, Kiyuk Chang, So‐Yeon Choi, Myung Ho Jeong, Bon‐Kwon Koo   +31 more
wiley   +1 more source

Capsaicin combined with dietary fiber prevents high‐fat diet associated aberrant lipid metabolism by improving the structure of intestinal flora

Food Science &Nutrition, Volume 11, Issue 1, Page 114-125, January 2023., 2023
In conclusion, notwithstanding the rats were fed a high‐fat diet, adding CAP plus fibers to the chow improved the lipidemia and increased the gut beneficial bacterial strains, while reducing the harmful ones as compared with CAP alone. Abstract Capsaicin (CAP) and dietary fibers are natural active ingredients that given separately do positively affect ...
Ting Gong, Yujing Zhou, Lei Zhang, Haizhu Wang, Min Zhang, Xiong Liu   +5 more
wiley   +1 more source

Leukocyte low density lipoprotein receptor (LDL-R) does not contribute to LDL clearance in vivo: bone marrow transplantation studies in the mouse

Journal of Lipid Research, 1997
The targeted disruption of the low density lipoprotein (LDL) receptor gene in mice results in accumulation of plasma LDL cholesterol and in predisposition to diet-induced aortic atherosclerosis.
S Fazio, A H Hasty, K J Carter, A B Murray, J O Price, M F Linton   +5 more
doaj