Results 51 to 60 of about 620,156 (317)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Contrasting roles for parvalbumin-expressing inhibitory neurons in two forms of adult visual cortical plasticity

open access: yeseLife, 2016
The roles played by cortical inhibitory neurons in experience-dependent plasticity are not well understood. Here we evaluate the participation of parvalbumin-expressing (PV+) GABAergic neurons in two forms of experience-dependent modification of primary ...
Eitan S Kaplan   +7 more
doaj   +1 more source

Genetic evidence for chromosome 4 loci influencing learning and memory

open access: yes, 2016
The Lewis (LEW) and SHR (Spontaneously Hypertensive Rats) inbred rat strains differ in several anxiety/emotionality and learning/memory-related behaviors.
Campelo, Clarissa Loureiro Chagas [UNIFESP]   +9 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Role of the hippocampus in systems consolidation of remote fear memory

open access: yesExperimental and Molecular Medicine
For decades, the processing and retrieval of memories over weeks or even years have been crucial and fundamental subjects in neuroscience. The hippocampus is essential for episodic memory, including associative fear memory.
Hyunmin Park, Bong-Kiun Kaang
doaj   +1 more source

Cerebellar implementation of movement sequences through feedback

open access: yeseLife, 2018
Most movements are not unitary, but are comprised of sequences. Although patients with cerebellar pathology display severe deficits in the execution and learning of sequences (Doyon et al., 1997; Shin and Ivry, 2003), most of our understanding of ...
Andrei Khilkevich   +3 more
doaj   +1 more source

Long-term memory guides resource allocation in working memory

open access: yesScientific Reports, 2020
Working memory capacity is incredibly limited and thus it is important to use this resource wisely. Prior knowledge in long-term memory can aid in efficient encoding of information by allowing for the prioritization of novel stimuli over familiar ones ...
Allison L. Bruning   +1 more
doaj   +1 more source

Working memory control dynamics follow principles of spatial computing

open access: yesNature Communications, 2023
It is unclear how cognitive computations are performed on sensory information. Here, neural evidence from working memory tasks suggests that the physical dimensions of cortical networks are used to update the status of sensory representations.
Mikael Lundqvist   +6 more
doaj   +1 more source

Correction of amblyopia in cats and mice after the critical period

open access: yeseLife, 2021
Monocular deprivation early in development causes amblyopia, a severe visual impairment. Prognosis is poor if therapy is initiated after an early critical period.
Ming-fai Fong   +4 more
doaj   +1 more source

The effect of choice on intentional and incidental memory [PDF]

open access: yes, 2021
Recent studies have revealed that memory performance is better when participants have the opportunity to make a choice regarding the experimental task (choice condition) than when they do not have such a choice (fixed condition).
Jiang, Ting   +6 more
core   +1 more source

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