Results 61 to 70 of about 2,058,783 (273)

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Multisensory gamma stimulation mitigates the effects of demyelination induced by cuprizone in male mice

open access: yesNature Communications
Demyelination is a common pathological feature in a wide range of diseases, characterized by the loss of myelin sheath and myelin-supporting oligodendrocytes.
Daniela Rodrigues-Amorim   +18 more
doaj   +1 more source

Working memory learning method and astrocytes number in different subfields of rat's Hippocampus [PDF]

open access: yes, 2008
The aim of this study was evaluation of the astrocytes number in different subfields of rat's Hippocampus after spatial learning with usage of Morris Water Maze technique and working memory method.
Abbas, P.   +4 more
core   +1 more source

Memory, learning and metacognition

open access: yesComptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie, 1998
Resume Un etre humain construit sa representation du monde a partir de quatre sources fondamentales: la perception, la memoire, l'inference et la communication. Faute de capacites d'apprentissage, un systeme qui traite de l'information ne serait pas un systeme cognitif authentique. Faute de memoire, un systeme serait incapable d'apprendre.
openaire   +3 more sources

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Pixel-wise programmability enables dynamic high-SNR cameras for high-speed microscopy

open access: yesNature Communications
High-speed wide-field fluorescence microscopy has the potential to capture biological processes with exceptional spatiotemporal resolution. However, conventional cameras suffer from low signal-to-noise ratio at high frame rates, limiting their ability to
Jie Zhang   +12 more
doaj   +1 more source

No evidence that monkeys attribute mental states to animated shapes in the Heider–Simmel videos

open access: yesScientific Reports, 2021
Human Theory of Mind (ToM) is so automatic and pervasive that we spontaneously attribute mental states to animated abstract shapes, as evidenced by the classic Heider–Simmel findings.
Jamie L. Schafroth   +3 more
doaj   +1 more source

Regulation of presynaptic Ca2+ channel abundance at active zones through a balance of delivery and turnover

open access: yeseLife, 2022
Voltage-gated Ca2+ channels (VGCCs) mediate Ca2+ influx to trigger neurotransmitter release at specialized presynaptic sites termed active zones (AZs). The abundance of VGCCs at AZs regulates neurotransmitter release probability (Pr), a key presynaptic ...
Karen L Cunningham   +3 more
doaj   +1 more source

Learning and memory in machines and animals : an AI model that accounts for some neurobiological data [PDF]

open access: yes, 1984
The CEL model of learning and memory (Components of Episodic Learning) [Granger 1982, 1983a, 1983b] provides a process model of certain aspects of learning and memory in animals and humans. The model consists of a set of asynchronous and semi-independent
Granger, Richard H., McNulty, Dale M.
core   +2 more sources

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