Advanced Science, EarlyView.ABSTRACT This special issue marking the University of Bath's 60th anniversary offers an opportunity to reflect on nearly a decade of research into the evolution of gene regulatory networks (GRNs) from members of the lab and elsewhere. Our goal is to understand how GRNs rewire and how new transcription factor (TF) functions evolve. Using an experimental
Tiffany B. Taylor, Alan M. Rice
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Advanced Science, EarlyView.An on‐demand ultra‐reconfigurable intelligent vision system with hierarchical reconfigurability from device to system levels is demonstrated. Through co‐design of a multi‐paradigm device, reconfigurable circuits, and adaptive system architecture/algorithms, the system enables seamless switching among spiking, non‐spiking, neuromorphic imaging (NI), and
Biyi Jiang +7 more
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Oakwood Court: inspection of FEFC-funded provision in non-sector establishments for students with learning difficulties and/or disabilities (Report from the Inspectorate; 1999-00) [PDF]
, 2000 Independent Establishment 20/00 Inspection of FEFC-Funded Provision in the non-sector establishment for students with learning difficulties and/or disabilities.
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Advanced Science, EarlyView.PtRhIr/Ru SAN@M nanozymes cross the blood–brain barrier and selectively accumulate in hemorrhagic brain regions. By mimicking multiple enzyme activities, they attenuate oxidative stress, modulate microglial polarization toward an anti‐inflammatory phenotype, inhibit ferroptosis, and promote neuronal repair.
Jiebo Li +17 more
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Royal West of England Residential School for the Deaf Inspection of FEFC-funded provision in non-sector establishments for students with learning difficulties and/or disabilities (Report from the Inspectorate; 1999-00) [PDF]
, 2000 Independent Establishment 19/00 Inspection of FEFC-Funded provision in non-sector establishments for students with learning difficulties and/or disabilities.
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Advanced Science, EarlyView.PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li +8 more
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Kisharon Centre Inspection of FEFC-funded provision in non-sector establishments for students with learning difficulties and/or disabilities [PDF]
, 2000 Independent Establishment 18/00 Inspection of FEFC-Funded provision in non-sector establishments for students with learning difficulties and/or disabilities.
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Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS
Advanced Science, EarlyView.ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi +4 more
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Queen Elizabeth's Foundation Brain Injury Centre Inspection of FEFC-funded provision in non-sector establishments for students with learning difficulties and/or disabilities (Report from the Inspectorate; 2000-01) [PDF]
, 2000 Independent Establishment 04/00 Inspection of FEFC-Funded Provision in non-sector establishments for students with learning difficulties and/or disabilities.
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