Results 61 to 70 of about 2,318,151 (292)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
EFL Students’ Self-Regulation in Online Interactions with Lecturers and Peers
Online learning is definitely advantageous in this current situation. Due to the technology, the teaching and learning process can continue despite the students and instructor/lecturer located in different places. This study aims to understand student’s
Nurvira Wardayani +4 more
doaj +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Grappling with Issues of Learning Science from Everyday Experiences: An Illustrative Case Study [PDF]
There are different perceptions among researchers with regard to the infusion of everyday experience in the teaching of science: 1) it hinders the learning of science concepts; or, 2) it increases the participation and motivation of students in science ...
Kim, M., Talaue, F., Tan, A.-L.
core +1 more source
A feedback model of perceptual learning and categorisation [PDF]
Top-down, feedback, influences are known to have significant effects on visual information processing. Such influences are also likely to affect perceptual learning.
Johnson, Mark H, Spratling, Michael W
core +2 more sources
Policy Interaction and Learning Equilibria [PDF]
This note studies fiscal–monetary policy interactions in an endogenous growth model with multiple assets. The “growth-rate Laffer curve” clarifies an important tension between economic growth and government revenue and reveals that higher economic growth does not always finance a larger budget deficit.
openaire +2 more sources
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Nous interrogeons les formes d’interactions des apprenants dans un parcours d’autoapprentissage guidé en langues. Le dispositif comprend un centre de ressources en langues, des entretiens et un journal de bord réflexif sur leurs activités dont certaines ...
Marco Cappellini +2 more
doaj +1 more source
Machine Learning Uncovers Food- and Excipient-Drug Interactions
Summary: Inactive ingredients and generally recognized as safe compounds are regarded by the US Food and Drug Administration (FDA) as benign for human consumption within specified dose ranges, but a growing body of research has revealed that many ...
Daniel Reker +8 more
doaj +1 more source
Factorization Machines (FMs) are a supervised learning approach that enhances the linear regression model by incorporating the second-order feature interactions.
Chua, Tat-Seng +5 more
core +1 more source

