Results 61 to 70 of about 2,318,151 (292)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

EFL Students’ Self-Regulation in Online Interactions with Lecturers and Peers

open access: yesIndonesian Journal of Educational Research and Review, 2022
Online learning is definitely advantageous in this current situation. Due to the technology, the teaching and learning process can continue despite the students and instructor/lecturer located in different places. This study aims to understand student’s
Nurvira Wardayani   +4 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Grappling with Issues of Learning Science from Everyday Experiences: An Illustrative Case Study [PDF]

open access: yes, 2013
There are different perceptions among researchers with regard to the infusion of everyday experience in the teaching of science: 1) it hinders the learning of science concepts; or, 2) it increases the participation and motivation of students in science ...
Kim, M., Talaue, F., Tan, A.-L.
core   +1 more source

A feedback model of perceptual learning and categorisation [PDF]

open access: yes, 2006
Top-down, feedback, influences are known to have significant effects on visual information processing. Such influences are also likely to affect perceptual learning.
Johnson, Mark H, Spratling, Michael W
core   +2 more sources

Policy Interaction and Learning Equilibria [PDF]

open access: yesSSRN Electronic Journal, 2009
This note studies fiscal–monetary policy interactions in an endogenous growth model with multiple assets. The “growth-rate Laffer curve” clarifies an important tension between economic growth and government revenue and reveals that higher economic growth does not always finance a larger budget deficit.
openaire   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Interactions plurielles d’étudiants en autoformation guidée et autonomisation | Interactions and Autonomization of Students in a Guided Self-Learning Environment

open access: yesCanadian Journal of Learning and Technology, 2016
Nous interrogeons les formes d’interactions des apprenants dans un parcours d’autoapprentissage guidé en langues. Le dispositif comprend un centre de ressources en langues, des entretiens et un journal de bord réflexif sur leurs activités dont certaines ...
Marco Cappellini   +2 more
doaj   +1 more source

Machine Learning Uncovers Food- and Excipient-Drug Interactions

open access: yesCell Reports, 2020
Summary: Inactive ingredients and generally recognized as safe compounds are regarded by the US Food and Drug Administration (FDA) as benign for human consumption within specified dose ranges, but a growing body of research has revealed that many ...
Daniel Reker   +8 more
doaj   +1 more source

Attentional Factorization Machines: Learning the Weight of Feature Interactions via Attention Networks

open access: yes, 2017
Factorization Machines (FMs) are a supervised learning approach that enhances the linear regression model by incorporating the second-order feature interactions.
Chua, Tat-Seng   +5 more
core   +1 more source

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