Results 41 to 50 of about 58,411 (259)

Efforts to Improve Scientific Literacy of Students through Guided Inquiry Learning Based on Local Wisdom of Baduy’s Society [PDF]

open access: yesJurnal Penelitian dan Pembelajaran IPA, 2017
The aim of this study was to determine the influence of guided inquiry learning model toward the improvement of students‟s scientific literacy in integrated science learning on environmental conservation concept based on local wisdom of Baduy‟s society ...
Asep Saefullah   +6 more
doaj   +3 more sources

Development of Distance Learning Concept with Graphic Machines Working Process Visualization [PDF]

open access: yesMATEC Web of Conferences, 2019
The paper presents the distance learning concept development by visualizing the work process of graphics machines. The basic goal is realized through the application development that includes machines simulations and their elements.
Zeljkovic Zeljko   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

POLA PENERIMAAN SISWA TUNANETRA DALAM PEMBELAJARAN MATEMATIKA DI SMPLB

open access: yesJurnal E-DuMath, 2015
The blind students have limitations in receiving information, they are only a hold of the senses of hearing and touch, so understanding of abstract mathematical objects understood through verbal description of teacher with concrete objects directly ...
Nurmitasari Nurmitasari
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

http://www.periodicos.letras.ufmg.br/index.php/textolivre/article/view/10912/9820

open access: yesTexto Livre: Linguagem e Tecnologia, 2016
This work seeks to reflect on how the Cognitive Linguistics – about the conceptual metaphor theory and embodiment – assiste the production processes and assessment of a virtual learning material for the course Anatomy for the Movement in the Degree ...
Siane Paula de Araújo   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Interpreter and Applied Development Environment for Learning Concepts of Object Oriented Programming [PDF]

open access: yesInternational Journal of Programming Languages and Applications, 2013
The programing languages are classified by its paradigms, some paradigms are easier to understand than others, or at least we have that impression. But when we learn our first language, what paradigm is the best? Many people could say that structured is better, because is a recipe to follow, or maybe an object oriented, because it-s a natural ...
Ever Mitta, Layla Hirsh
openaire   +6 more sources

Cortical knowledge structures guide word concept learning

open access: yesNature Communications
Human word concept learning leverages prior knowledge to generalize from limited exemplars, yet its neural implementation remains unclear. We developed a Neural Bayesian Model (NBM) that incorporates neural representational priors to explain word concept
Guangyao Zhang   +5 more
doaj   +1 more source

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