Results 51 to 60 of about 858,456 (300)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Introduction by Terry Mayes to Part 1 of Littlejohn, A. (2003) Reusing Online Resources: Vision and Theoretical Perspectives

open access: yesJournal of Interactive Media in Education, 2010
: Reading the five chapters in this part of the book has made me realize that, as is often the case with attitudes towards topics that are not often revisited, my view of learning objects was based on a simplified and rather crude version, based on ...
J. Terry Mayes
doaj   +1 more source

Persuasive Technology for Learning in Business Context [PDF]

open access: yes, 2013
"Persuasive Design is a relatively new concept which employs general principles of persuasion that can be implemented in persuasive technology. This concept has been introduced by BJ Fogg in 1998, who since then has further extended it to use computers ...
Behringer, R   +6 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Automatic Extraction and Labelling of Memorial Objects From 3D Point Clouds

open access: yesJournal of Computer Applications in Archaeology, 2021
This research addresses the problem of automatic extraction of memorial objects from cultural heritage sites represented as scenes of 3D point clouds. Point clouds provide a fine spatial resolution and accurate proxy of the real world.
Nicholas Arnold   +3 more
doaj   +1 more source

Associating low-level features with semantic concepts using video objects and relevance feedback [PDF]

open access: yes, 2005
The holy grail of multimedia indexing and retrieval is developing algorithms capable of imitating human abilities in distinguishing and recognising semantic concepts within the content, so that retrieval can be based on ”real world” concepts that come ...
Murphy, Noel   +3 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

POLA PENERIMAAN SISWA TUNANETRA DALAM PEMBELAJARAN MATEMATIKA DI SMPLB

open access: yesJurnal E-DuMath, 2015
The blind students have limitations in receiving information, they are only a hold of the senses of hearing and touch, so understanding of abstract mathematical objects understood through verbal description of teacher with concrete objects directly ...
Nurmitasari Nurmitasari
doaj   +1 more source

Development of Distance Learning Concept with Graphic Machines Working Process Visualization [PDF]

open access: yesMATEC Web of Conferences, 2019
The paper presents the distance learning concept development by visualizing the work process of graphics machines. The basic goal is realized through the application development that includes machines simulations and their elements.
Zeljkovic Zeljko   +4 more
doaj   +1 more source

Peningkatan Kecerdasan Anak Usia Dini Melalui Pembelajaran Integratif Sains dan Al-Qur’an

open access: yesAl Quds: Jurnal Studi Alquran dan Hadis, 2023
Improving Early Childhood Intelligence Through Integrative Learning of Science and the Qur'an The Qur'an and science are a whole that cannot be separated.
Baeti Rohman   +4 more
doaj   +1 more source

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