Results 31 to 40 of about 646,029 (255)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Project-based learning (PjBL) strategies with gamification
Inovasi KurikulumThis research aims to develop and test the effectiveness of the Project-Based Learning (PjBL) learning model integrated with gamification (G-PJBL) to increase student engagement and learning outcomes in Graphic and Visual Media courses. The background to
Putri Fadilla Azzahra Fazarini +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Academic Goal Profiles and Learning Strategies in Adolescence
Frontiers in Psychology, 2018 The objective of this study was to verify whether or not a combination of academic goals may be established in different profiles of high school students.
María Carmen Martínez-Monteagudo +4 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Learning strategies in amnesia [PDF]
Neuroscience & Biobehavioral Reviews, 2008 Previous research suggests that early performance of amnesic individuals in a probabilistic category learning task is relatively unimpaired. When combined with impaired declarative knowledge, this is taken as evidence for the existence of separate implicit and explicit memory systems.
Speekenbrink, M, Channon, S, Shanks, DR
openaire +3 more sources
Dubai Medical JournalObjective: The study was conducted to assess the correlation between approaches to metacognitive learning and the academic achievement of nursing students and identify variables that predict academic performance.
Rasha Kadri Ibrahim, Atika Khalaf
doaj +1 more source
European Journal of Investigation in Health, Psychology and Education, 2023 Meeting a student’s autonomy, competence, and relatedness needs is one of the conditions to help him/her learn effectively. In this study, we aim to understand how teacher support (relationship with students, their autonomy support) and general classroom
Agne Brandisauskiene +2 more
doaj +1 more source