Results 201 to 210 of about 811,099 (259)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Journal of the American College of Surgeons, 2003
The 20th century has been called the “Century of the Surgeon,” and surely it was. But who would we nominate to be the “Surgeon of the Century?” I want to place in nomination the name of a surgeon who worked in Europe and America. He developed a number of new surgical procedures, lived in four different countries during his surgical career, and studied ...
openaire +2 more sources
The 20th century has been called the “Century of the Surgeon,” and surely it was. But who would we nominate to be the “Surgeon of the Century?” I want to place in nomination the name of a surgeon who worked in Europe and America. He developed a number of new surgical procedures, lived in four different countries during his surgical career, and studied ...
openaire +2 more sources
This chapter reviews the migration crises that shaped European identity, political discourse, and historical narratives, including Poland's role during the 2021 refugee standoff at the Polish–Belarusian border. It highlights how Prime Minister Mateusz Morawiecki used the hashtag #WeDefendEurope and invoked the myth of Antemurale Christianitatis to ...
Félix Krawatzek +3 more
openaire +1 more source
Félix Krawatzek +3 more
openaire +1 more source
Proceedings of the 8th Software Security, Protection, and Reverse Engineering Workshop, 2018
Malware authors make use of several techniques to obfuscate code from reverse engineering tools such as IdaPro. Typically, these techniques tend to be effective for about three to six instructions, but eventually the tools can properly disassemble the remaining code once the tool is again synchronized with the operation codes.
William Mahoney +3 more
openaire +2 more sources
Malware authors make use of several techniques to obfuscate code from reverse engineering tools such as IdaPro. Typically, these techniques tend to be effective for about three to six instructions, but eventually the tools can properly disassemble the remaining code once the tool is again synchronized with the operation codes.
William Mahoney +3 more
openaire +2 more sources
Journal of Morphology, 1994
AbstractThe properties of a function G(x, y) of 2‐dimensional Cartesian coordinates x, y can be used to obtain complex shapes through a nonlinear iterative procedure. It is conjectured that at least some biological shapes are determined by this procedure, and those of leaves are considered as a test of the hypothesis.
R J, Bird, F, Hoyle
openaire +2 more sources
AbstractThe properties of a function G(x, y) of 2‐dimensional Cartesian coordinates x, y can be used to obtain complex shapes through a nonlinear iterative procedure. It is conjectured that at least some biological shapes are determined by this procedure, and those of leaves are considered as a test of the hypothesis.
R J, Bird, F, Hoyle
openaire +2 more sources