Adding MASP1 to the lectin pathway-Leprosy association puzzle: Hints from gene polymorphisms and protein levels. [PDF]
PLoS Neglected Tropical Diseases, 2020 BackgroundDeposition of complement factors on Mycobacterium leprae may enhance phagocytosis. Such deposition may occur through the lectin pathway of complement.
Hellen Weinschutz Mendes +5 more
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Complement activation promoted by the lectin pathway mediates C3aR-dependent sarcoma progression and immunosuppression. [PDF]
Nat Cancer, 2021 Magrini E +19 more
europepmc +2 more sources
Extensive Basal Level Activation of Complement Mannose-Binding Lectin-Associated Serine Protease-3: Kinetic Modeling of Lectin Pathway Activation Provides Possible Mechanism [PDF]
Frontiers in Immunology, 2017 Serine proteases (SPs) are typically synthesized as precursors, termed proenzymes or zymogens, and the fully active form is produced via limited proteolysis by another protease or by autoactivation.
Gábor Oroszlán +6 more
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The role of the lectin pathway of the complement system in SARS-CoV-2 lung injury. [PDF]
Transl Res, 2021 Malaquias MAS +13 more
europepmc +2 more sources
Endothelial injury and thrombotic microangiopathy in COVID-19: Treatment with the lectin-pathway inhibitor narsoplimab. [PDF]
Immunobiology, 2020 Rambaldi A +16 more
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Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19. [PDF]
J Innate Immun, 2023 Götz MP +8 more
europepmc +3 more sources
Lectin pathway effector enzyme mannan‐binding lectin‐associated serine protease‐2 can activate native complement C3 in absence of C4 and/or C2 [PDF]
The FASEB Journal, 2017 Sadam Yaseen +15 more
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Lectin complement pathway and diabetes mellitus in the pathogenesis of membranous nephropathy [PDF]
Folia Medica, 2023 Introduction: Membranous nephropathy (MN) is a glomerulonephritis with growing incidence and its pathogenesis still remains unclear, despite discoveries of many new antigens.
Irina Y. Zdravkova +2 more
doaj +3 more sources
Mitochondria and the Lectin Pathway of Complement [PDF]
Journal of Biological Chemistry, 2013 Mitochondria, the powerhouses of our cells, are remnants of a eubacterial endosymbiont. Notwithstanding the evolutionary time that has passed since the initial endosymbiotic event, mitochondria have retained many hallmarks of their eubacterial origin. Recent studies have indicated that during perturbations of normal homeostasis, such as following acute
Brinkmann, Christel R +8 more
openaire +6 more sources
Remote ischemic preconditioning does not influence lectin pathway protein levels in head and neck cancer patients undergoing surgery. [PDF]
PLoS One, 2020 Frederiksen K +5 more
europepmc +3 more sources