The Influence of the Lectin Pathway of Complement Activation on Infections of the Respiratory System. [PDF]
Front Immunol, 2020 Lung diseases are among the leading causes of morbidity and mortality. Complement activation may prevent a variety of respiratory infections, but on the other hand, could exacerbate tissue damage or contribute to adverse side effects. In this review, the
Świerzko AS, Cedzyński M.
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Endothelial injury and thrombotic microangiopathy in COVID-19: Treatment with the lectin-pathway inhibitor narsoplimab. [PDF]
Immunobiology, 2020 Rambaldi A +16 more
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Lectin complement pathway and diabetes mellitus in the pathogenesis of membranous nephropathy [PDF]
Folia Medica, 2023 Introduction: Membranous nephropathy (MN) is a glomerulonephritis with growing incidence and its pathogenesis still remains unclear, despite discoveries of many new antigens.
Irina Y. Zdravkova +2 more
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Mitochondria and the Lectin Pathway of Complement [PDF]
Journal of Biological Chemistry, 2013 Mitochondria, the powerhouses of our cells, are remnants of a eubacterial endosymbiont. Notwithstanding the evolutionary time that has passed since the initial endosymbiotic event, mitochondria have retained many hallmarks of their eubacterial origin. Recent studies have indicated that during perturbations of normal homeostasis, such as following acute
Brinkmann, Christel R +8 more
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Lectin-conjugated pH-responsive mesoporous silica nanoparticles for targeted bone cancer treatment [PDF]
Acta Biomaterialia. 65, 393-404 (2018), 2021 A novel multifunctional nanodevice based in doxorubicin (DOX)- loaded mesoporous silica nanoparticles (MSNs) as nanoplatforms for the assembly of different building blocks has been developed for bone cancer treatment. These building blocks consists of: i) a polyacrylic acid (PAA) capping layer grafted to MSNs via an acid-cleavable acetal linker, to ...
arxiv +1 more source
Lectin pathway proteins of the complement system in normotensive pregnancy and pre‐eclampsia [PDF]
American Journal of Reproductive Immunology, 2019 The lectin pathway of the complement system may be involved in the pathogenesis of pre‐eclampsia. We aimed to investigate changes in serum concentrations of a broad range of lectin pathway proteins during normal pregnancy and their association with pre ...
Julie Brogaard Larsen +6 more
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Lectins and traffic in the secretory pathway [PDF]
FEBS Letters, 2000 Evidence is accumulating that intracellular animal lectins play important roles in quality control and glycoprotein sorting along the secretory pathway. Calnexin and calreticulin in conjunction with associated chaperones promote correct folding and oligomerization of many glycoproteins in the endoplasmic reticulum (ER).
Hauri, H. +3 more
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Pilot study: deficiency of mannose-binding lectin-dependent lectin pathway, a novel modulator in outcome from pancreatic islet auto-transplantation. [PDF]
Ann Transl Med, 2020 Chung WY +9 more
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Should MASP-2 Deficiency Be Considered a Primary Immunodeficiency? Relevance of the Lectin Pathway. [PDF]
J Clin Immunol, 2020 Mannose-binding lectin (MBL)-associated serine protease-2 (MASP-2) is an indispensable enzyme for the activation of the lectin pathway of complement. Its deficiency is classified as a primary immunodeficiency associated to pyogenic bacterial infections ...
García-Laorden MI +16 more
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Remote ischemic preconditioning does not influence lectin pathway protein levels in head and neck cancer patients undergoing surgery. [PDF]
PLoS One, 2020 Frederiksen K +5 more
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