Signalling C-type lectins in antimicrobial immunity. [PDF]
PLoS Pathogens, 2013 Since it was first proposed that the innate immune system could recognise conserved microbial-associated molecular patterns (or PAMPs) through inherited receptors expressed by the host (termed pattern recognition receptors, or PRRs), several families of ...
Rebecca A Drummond, Gordon D Brown
doaj +10 more sources
C-type lectins and extracellular vesicles in virus-induced NETosis
Journal of Biomedical Science, 2021 Dysregulated formation of neutrophil extracellular traps (NETs) is observed in acute viral infections. Moreover, NETs contribute to the pathogenesis of acute viral infections, including those caused by the dengue virus (DV) and severe acute respiratory ...
Pei-Shan Sung, Shie-Liang Hsieh
doaj +2 more sources
Transmission-blocking antibodies against mosquito C-type lectins for dengue prevention. [PDF]
PLoS Pathogens, 2014 C-type lectins are a family of proteins with carbohydrate-binding activity. Several C-type lectins in mammals or arthropods are employed as receptors or attachment factors to facilitate flavivirus invasion.
Yang Liu +8 more
doaj +2 more sources
Characterization of C-type lectins reveals an unexpectedly limited interaction between Cryptococcus neoformans spores and Dectin-1. [PDF]
PLoS ONE, 2017 Phagocytosis by innate immune cells is an important process for protection against multiple pathologies and is particularly important for resistance to infection.
Naomi M Walsh +4 more
doaj +2 more sources
From Snake Venom’s Disintegrins and C-Type Lectins to Anti-Platelet Drugs
Toxins, 2019 Snake venoms are attractive natural sources for drug discovery and development, with a number of substances either in clinical use or in research and development.
Philip Lazarovici +2 more
doaj +2 more sources
Identification of CLEC10A as a human lectin for pancreatic ductal adenocarcinoma [PDF]
Scientific ReportsThe mechanism by which glycans in pancreatic ductal adenocarcinoma (PDAC) interact with human endogenous lectins in the tumor microenvironment remains largely unknown.
Shuntaro Tsukamoto +9 more
doaj +2 more sources
Integrative analysis workflow for the structural and functional classification of C-type lectins
BMC Bioinformatics, 2011 Background It is important to understand the roles of C-type lectins in the immune system due to their ubiquity and diverse range of functions in animal cells.
Koh Geoffrey +8 more
doaj +2 more sources
Targeting the C-type Lectins-Mediated Host-Pathogen Interactions with Dextran
Journal of Pharmacy & Pharmaceutical Sciences, 2014 Dextran, the α-1,6-linked glucose polymer widely used in biology and medicine, promises new applications. Linear dextran applied as a blood plasma substitute demonstrates a high rate of biocompatibility.
Sergey Pustylnikov +3 more
doaj +2 more sources
Molecular Cloning and Characteristics of a Lectin from the Bivalve Glycymeris yessoensis
Marine Drugs, 2023 C-type lectins (CTLs) are a family of carbohydrate-binding proteins that mediate multiple biological events, including adhesion between cells, the turnover of serum glycoproteins, and innate immune system reactions to prospective invaders.
Tatyana O. Mizgina +9 more
doaj +1 more source
Marine Drugs, 2022 Lectins are a unique group of nonimmune carbohydrate-binding proteins or glycoproteins that exhibit specific and reversible carbohydrate-binding activity in a non-catalytic manner.
Mirja Kaizer Ahmmed +16 more
doaj +1 more source