Results 1 to 10 of about 30,035 (192)

C-type lectins in immunity : recent developments [PDF]

Current Opinion in Immunology, 2014
Acknowledgements We thank the Wellcome Trust (Grant No. 102705) and Wellcome Trust Strategic Award in Medical Mycology and Fungal Immunology (Grant No. 97377) for funding.
Brown, Gordon D, Dambuza, Ivy M
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Signalling C-Type Lectins in Antimicrobial Immunity [PDF]

PLoS Pathogens, 2013
Funding: This work was funded by the Wellcome Trust, Medical Research Council and the University of Aberdeen. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer ...
Brown, Gordon D., Drummond, Rebecca A.
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C-type lectins in HIV-1 infection [PDF]

Retrovirology, 2011
Adaptive immune responses by dendritic cells (DCs) are controlled by pattern recognition receptors such as Toll-like receptors (TLRs) and C-type lectins. C-type lectins interact with carbohydrate structures on pathogens. Upon pathogen binding, C-type lectins trigger signaling pathways that induce specific cytokines to dictate T cell polarization. Thus,
Geijtenbeek, Teunis BH
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C-Type Lectin Receptors in Asthma [PDF]

Frontiers in Immunology, 2018
Asthma is a heterogeneous disease that affects approximately 300 million people worldwide, largely in developed countries. The etiology of the disease is poorly understood, but is likely to involve specific innate and adaptive responses to inhaled microbial components that are found in allergens.
Gordon D. Brown, Gordon D. Brown, Frank Brombacher, Frank Brombacher, Sabelo Hadebe, Sabelo Hadebe   +5 more
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C-type lectins and phagocytosis

Immunobiology, 2009
To recognise and respond to pathogens, germ-line encoded pattern recognition receptors (PRRs) bind to conserved microbial structures and activate host defence systems, including microbial uptake by phagocytosis. Phagocytosis is a complex process that is instrumental in the control of extracellular pathogens, and this activity is mediated by several ...
Kerrigan, Ann, Brown, Gordon D
openaire   +4 more sources

Recent insights into structures and functions of C-type lectins in the immune system [PDF]

, 2015
The majority of the C-type lectin-like domains in the human genome likely to bind sugars have been investigated structurally, although novel mechanisms of sugar binding are still being discovered.
Drickamer, K, Taylor, ME
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The distribution of lectins across the phylum Nematoda : a genome-wide search [PDF]

, 2017
Nematodes are a very diverse phylum that has adapted to nearly every ecosystem. They have developed specialized lifestyles, dividing the phylum into free-living, animal, and plant parasitic species. Their sheer abundance in numbers and presence in nearly
Bauters, Lander, Gheysen, Godelieve, Naalden, Diana   +2 more
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Expression of DC-SIGN and DC-SIGNR on human sinusoidal endothelium: a role for capturing hepatitis C virus particles. [PDF]

, 2006
Hepatic sinusoidal endothelial cells are unique among endothelial cells in their ability to internalize and process a diverse range of antigens. DC-SIGNR, a type 2 C-type lectin expressed on liver sinusoids, has been shown to bind with high affinity to ...
Adam Jennings, Alvarez, Appelmelk, Bartosch, Bashirova, Cormier, Cormier, Crispe, David H. Adams, Ebner, Engering, Feinberg, Flint, Gardner, Geijtenbeek, Grant, Guo, Halary, Hsu, Jameson, Jane A. McKeating, Jie Zhang, Klimstra, Knolle, Krutzik, Lalor, Lasala, Lee, Limmer, Lindenbach, Lindenbach, Lozach, Lozach, Lozach, Ludwig, Maeda, Marzi, McCully, Mitchell, Mukhtar, Patricia F. Lalor, Phoebe J. Sun, Pileri, Pohlmann, Pohlmann, Pohlmann, Pohlmann, Puig-Kroger, Relloso, Romani, Seternes, Simmons, Soilleux, Stefan Hubscher, Tassaneetrithep, Trumpfheller, Turville, Wai K. Lai, Wakita, Yang, Zhang, Zhong   +61 more
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Crystal Structure of the C-type Lectin-like Domain from the Human Hematopoietic Cell Receptor CD69 [PDF]

, 2001
CD69, one of the earliest specific antigens acquired during lymphoid activation, acts as a signal-transducing receptor involved in cellular activation events, including proliferation and induction of specific genes.
Andrea S. Llera, Bajorath, Bates, Bléry, Borrego, Boyington, Braud, Brown, Brünger, Cebrián, Childs, Chothia, Cowtan, Day, De Maria, Drickamer, Drickamer, Drickamer, Esnouf, Fernando Viedma, Francisco Sánchez-Madrid, Garboczi, Gouet, Hamann, Hubbard, Hubbard, Jones, José Tormo, Kabsch, Lanier, Lanier, Laskowski, Laskowski, Lauzurica, Lee, Lo Conte, López-Botet, López-Botet, López-Cabrera, Marzio, Matsumoto, McDonald, Merrit, Nakamura, Navaza, Nicholls, Otwinowski, Read, Santis, Stuart, Studier, Suzuki, Sánchez-Mateos, Sánchez-Mateos, Testi, Testi, Testi, Tormo, Ugolini, Weis, Weis, Weis, Ziegler, Zingoni   +63 more
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Evolution and Immune Function of Fish Lectins [PDF]

, 2016
Lectins are sugar-binding proteins widely distributed among animals, plants, and microbial taxon, involved in diverse biological processes. In both invertebrates and vertebrates, they play key roles in nonself recognition and immune responses, such as ...
Ahmad, Ahmed, Ahmed, Arason, Argayosa, Ballarin, Bianchet, Bianchet, Brewer, Cammarata, Cammarata, Cammarata, Cammarata, Cammarata, Camus, Casadevall, Chen, Cooper, Earl, Eddie, Ewart, Fujita, Gabius, Garner, Gonzalez, Hernandez, Hirabayashi, Honda, Hosono, Houzelstein, Inagawa, Jackson, Jia, Jimbo, Kaltner, Kania, Kilpatrick, Kondo, Lam, Levroney, Liao, Liu, Lopez, Loris, Matsui, Mitra, Muramoto, Nakao, Nikolakopoulou, Nitta, Noguchi, Odom, Ogawa, Ottinger, Ourth, Ozeki, Pan, Parisi, Paulson, Qiu, Rabinovich, Russel, Salerno, Sato, Schwarz, Sharon, Sharon, Shiina, Shirai, Silva, Takahashi, Tasumi, Tateno, Tateno, Tateno, Teichberg, Terada, Thongda, Tsutsui, Tsutsui, Tsutsui, Turner, Vakonakis, Vasta, Vasta, Vasta, Vasta, Vasta, Vasta, Vasta, Vitved, Watanabe, Watkins, Yano, Zelensky, Zhang   +95 more
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