Results 181 to 190 of about 43,176 (288)

C-type lectins and innate immunity in barramundi

C-type lectins and innate immunity in barramundi. The project aims to identify mannan binding lectins (MBL), key components of innate immunity, in barramundi and to develop quantitative assays for MBL.

core  

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Lipid nanoparticle formulations including stereochemically defined glycomacromolecules for delivery of saRNA. [PDF]

Chem Sci
Becker J, Dias-Barbieri B, Shattock RJ, Becer CR.   +3 more
europepmc   +1 more source

CLEC14A correlates with neutrophil infiltration in hepatocellular carcinoma and mediates neutrophil recruitment across liver endothelial cells

The Journal of Pathology, EarlyView.
Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related deaths globally, and cases are predicted to rise dramatically over the next few years. Overcoming the immune microenvironment in HCC remains a challenge, and innate immune populations such as tumour‐associated neutrophils can potentially impair the success of immunotherapy ...
Joanne M O'Rourke, Dean Kavanagh, Ayla O'Keeffe, Kylie Savoye, Kaiyi Yang, Daniel A Patten, Catherine E Willoughby, Josep M Llovet, Georgiana Neag, Helen L Reeves, Peter W Hewett, Neena Kalia, Tahir Shah, Yuk Ting Ma, Kelly Hunter, Joe Flint, Jack L McMurray, Owen Cain, Fabian Spill, Derek A Mann, Amy J Naylor, Victoria Heath, Christopher J Weston, Roy Bicknell, Shishir Shetty   +24 more
wiley   +1 more source

Protein Fraction and Derived Peptides from <i>Amaranthus hypochondriacus</i>: A Preliminary In Vitro Study of Cytotoxic Activity in Cancer Cell Lines. [PDF]

Int J Mol Sci
Reséndiz-Otero F, Valadez-Vega C, Velázquez-Morales BP, Bernardino-Nicanor A, Velasco-Azorsa R, Betanzos-Cabrera G, Salazar-Campos A, Muñoz-Pérez VM, Morales-González JA.   +8 more
europepmc   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Applications of Plant Lectins in Detection and Targeted Therapy of Urological Cancers. [PDF]

Drug Des Devel Ther
Long Z, Li Q, Shi F, Li F, Zang J.
europepmc   +1 more source

Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy

PROTEOMICS, EarlyView.
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling, Dounia Bouragba, Elisa Negroni, Capucine Trollet, Margit Zweyer, Dieter Swandulla, Kay Ohlendieck   +6 more
wiley   +1 more source

The C-type lectin AcCTL5 from <i>Apis cerana</i> mediates anti-<i>Nosema ceranae</i> defense via agglutination and hemolymph melanization. [PDF]

Virulence
Li D, Huang T, Hai Q, Ma Q, Liu X, Dang X, Ma Z, Xu J, Zhou Z.   +8 more
europepmc   +1 more source

Proteome‐Wide Analysis of Palmitoylated Proteins in Macrophages Reveals Novel Insights Into Early Immune Signaling

PROTEOMICS, EarlyView.
ABSTRACT Protein S‐palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains incompletely understood.
Hyojung Kim, Jiraphorn Issara‐Amphorn, Sung Hwan Yoon, Anirban Banerjee, Aleksandra Nita‐Lazar   +4 more
wiley   +1 more source