Results 11 to 20 of about 30,220 (239)

Signalling C-type lectins in antimicrobial immunity. [PDF]

PLoS Pathogens, 2013
Funding: This work was funded by the Wellcome Trust, Medical Research Council and the University of Aberdeen. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer ...
Rebecca A Drummond, Gordon D Brown
doaj   +7 more sources

The distribution of lectins across the phylum Nematoda : a genome-wide search [PDF]

, 2017
Nematodes are a very diverse phylum that has adapted to nearly every ecosystem. They have developed specialized lifestyles, dividing the phylum into free-living, animal, and plant parasitic species. Their sheer abundance in numbers and presence in nearly
Bauters, Lander, Gheysen, Godelieve, Naalden, Diana   +2 more
core   +6 more sources

Evolution and Immune Function of Fish Lectins [PDF]

, 2016
Lectins are sugar-binding proteins widely distributed among animals, plants, and microbial taxon, involved in diverse biological processes. In both invertebrates and vertebrates, they play key roles in nonself recognition and immune responses, such as ...
Ahmad, Ahmed, Ahmed, Arason, Argayosa, Ballarin, Bianchet, Bianchet, Brewer, Cammarata, Cammarata, Cammarata, Cammarata, Cammarata, Camus, Casadevall, Chen, Cooper, Earl, Eddie, Ewart, Fujita, Gabius, Garner, Gonzalez, Hernandez, Hirabayashi, Honda, Hosono, Houzelstein, Inagawa, Jackson, Jia, Jimbo, Kaltner, Kania, Kilpatrick, Kondo, Lam, Levroney, Liao, Liu, Lopez, Loris, Matsui, Mitra, Muramoto, Nakao, Nikolakopoulou, Nitta, Noguchi, Odom, Ogawa, Ottinger, Ourth, Ozeki, Pan, Parisi, Paulson, Qiu, Rabinovich, Russel, Salerno, Sato, Schwarz, Sharon, Sharon, Shiina, Shirai, Silva, Takahashi, Tasumi, Tateno, Tateno, Tateno, Teichberg, Terada, Thongda, Tsutsui, Tsutsui, Tsutsui, Turner, Vakonakis, Vasta, Vasta, Vasta, Vasta, Vasta, Vasta, Vasta, Vitved, Watanabe, Watkins, Yano, Zelensky, Zhang   +95 more
core   +1 more source

C-Type Lectin Receptors in Asthma [PDF]

Frontiers in Immunology, 2018
Asthma is a heterogeneous disease that affects approximately 300 million people worldwide, largely in developed countries. The etiology of the disease is poorly understood, but is likely to involve specific innate and adaptive responses to inhaled microbial components that are found in allergens.
Sabelo Hadebe, Sabelo Hadebe, Frank Brombacher, Frank Brombacher, Gordon D. Brown, Gordon D. Brown   +5 more
openaire   +4 more sources

How C-type lectins detect pathogens. [PDF]

Cellular microbiology, 2005
Glycosylation of proteins has proven extremely important in a variety of cellular processes, including enzyme trafficking, tissue homing and immune functions. In the past decade, increasing interest in carbohydrate-mediated mechanisms has led to the identification of novel carbohydrate-recognizing receptors expressed on cells of the immune system ...
Cambi, A., Koopman, M., Figdor, C.G.
openaire   +5 more sources

Lectin receptors expressed on myeloid cells [PDF]

, 2016
Lectins recognize a diverse array of carbohydrate structures and perform numerous essential biological functions. Here we focus on only two families of lectins, the Siglecs and C-type lectins.
Brown, Gordon D., Crocker, Paul R.
core   +2 more sources

Molecular basis for intestinal mucin recognition by galectin-3 and C-type lectins [PDF]

, 2018
Intestinal mucins trigger immune responses upon recognition by dendritic cells via protein–carbohydrate interactions. We used a combination of structural, biochemical, biophysical, and cell-based approaches to decipher the specificity of the interaction ...
Gunning, A. Patrick, Juge, Nathalie, Kavanaugh, Devon W., Kawasaki, Norihito, Latousakis, Dimitrios, Leclaire, Charlotte, Lecointe, Karine, Mackenzie, Donald A., Tribolo, Sandra, Wittmann, Alexandra   +9 more
core   +1 more source

A novel mechanism for binding of galactose-terminated glycans by the C-type carbohydrate recognition domain in blood dendritic cell antigen 2 [PDF]

, 2015
Blood dendritic cell antigen 2 (BDCA-2; also designated CLEC4C or CD303) is uniquely expressed on plasmacytoid dendritic cells. Stimulation of BDCA-2 with antibodies leads to an anti-inflammatory response in these cells, but the natural ligands for the ...
Drickamer, K, Dungarwalla, T, Feinberg, H, Jégouzo, SAF, Taylor, ME, Weis, WI   +5 more
core   +1 more source

C-type lectins and phagocytosis

Immunobiology, 2009
To recognise and respond to pathogens, germ-line encoded pattern recognition receptors (PRRs) bind to conserved microbial structures and activate host defence systems, including microbial uptake by phagocytosis. Phagocytosis is a complex process that is instrumental in the control of extracellular pathogens, and this activity is mediated by several ...
Kerrigan, Ann, Brown, Gordon D
openaire   +3 more sources

Crystal Structure of the C-type Lectin-like Domain from the Human Hematopoietic Cell Receptor CD69 [PDF]

, 2001
CD69, one of the earliest specific antigens acquired during lymphoid activation, acts as a signal-transducing receptor involved in cellular activation events, including proliferation and induction of specific genes.
Andrea S. Llera, Bajorath, Bates, Bléry, Borrego, Boyington, Braud, Brown, Brünger, Cebrián, Childs, Chothia, Cowtan, Day, De Maria, Drickamer, Drickamer, Drickamer, Esnouf, Fernando Viedma, Francisco Sánchez-Madrid, Garboczi, Gouet, Hamann, Hubbard, Hubbard, Jones, José Tormo, Kabsch, Lanier, Lanier, Laskowski, Laskowski, Lauzurica, Lee, Lo Conte, López-Botet, López-Botet, López-Cabrera, Marzio, Matsumoto, McDonald, Merrit, Nakamura, Navaza, Nicholls, Otwinowski, Read, Santis, Stuart, Studier, Suzuki, Sánchez-Mateos, Sánchez-Mateos, Testi, Testi, Testi, Tormo, Ugolini, Weis, Weis, Weis, Ziegler, Zingoni   +63 more
core   +1 more source