Results 71 to 80 of about 1,729,582 (215)

Turning-off Signaling by Siglecs, Selectins and Galectins: Chemical Inhibition of Glycan-dependent Interactions in Cancer

open access: yesFrontiers in Oncology, 2016
Aberrant glycosylation, a common feature associated with malignancy, has been implicated in important events during cancer progression. Our understanding of the role of glycans in cancer has grown exponentially in the last few years, concurrent with ...
Alejandro Javier Cagnoni   +5 more
doaj   +1 more source

Developments in plant breeding for improved nutritional quality of soya beans II. Anti-nutritional factors [PDF]

open access: yes, 2000
Nutritional value of most plant materials is limited by the presence of numerous naturally occurring compounds which interfere with nutrient digestion and absorption.
Clarke, E, Wiseman, J
core   +1 more source

Distinct usage of three C-type lectins by Japanese encephalitis virus: DC-SIGN, DC-SIGNR, and LSECtin

open access: yesArchives of Virology, 2014
Infection with West Nile virus and dengue virus, two mosquito-borne flaviviruses, is enhanced by two calcium-dependent lectins: dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN), and its related molecule (DC-SIGNR).
M. Shimojima   +4 more
semanticscholar   +1 more source

C-type Lectin Receptors for Tumor Eradication: Future Directions [PDF]

open access: yesCancers, 2011
Dendritic cells are key regulators in directing immune responses and therefore are under extensive research for the induction of anti-tumor responses. DCs express a large array of receptors by which they scan their surroundings for recognition and uptake of pathogens.
Streng-Ouwehand, Ingeborg   +2 more
openaire   +4 more sources

Taxonomic Distribution and Molecular Evolution of Mytilectins

open access: yesMarine Drugs, 2023
R-type lectins are a widespread group of sugar-binding proteins found in nearly all domains of life, characterized by the presence of a carbohydrate-binding domain that adopts a β-trefoil fold.
Marco Gerdol   +6 more
doaj   +1 more source

Platelets and galectins [PDF]

open access: yes, 2014
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core   +1 more source

Tetranectin, a trimeric plasminogen‐binding C‐type lectin [PDF]

open access: yesProtein Science, 1997
AbstractTetranectin, a plasminogen‐binding protein belonging to the family of C‐type lectins, was expressed in E. coli and converted to its native form by in vitro refolding and proteolytic processing. Recombinant tetranectin—as well as natural tetranectin from human plasma—was shown by chemical cross‐linking analysis and SDS‐PAGE to be a homo‐trimer ...
Holtet, Thor L.   +4 more
openaire   +3 more sources

A new player in the game: platelet-derived extracellular vesicles in dengue hemorrhagic fever

open access: yesPlatelets, 2020
Thrombocytopenia and vascular leakage are clinical hallmarks in dengue hemorrhagic fever. Sung et al. present a new mechanism where platelet-derived extracellular vesicles participate in increasing vascular permeability during dengue virus infection in ...
Marisol Perez-Toledo   +1 more
doaj   +1 more source

Variation of Neisseria gonorrhoeae lipooligosaccharide directs dendritic cell-induced T helper responses. [PDF]

open access: yesPLoS Pathogens, 2009
Gonorrhea is one of the most prevalent sexually transmitted diseases in the world. A naturally occurring variation of the terminal carbohydrates on the lipooligosaccharide (LOS) molecule correlates with altered disease states.
Sandra J van Vliet   +8 more
doaj   +1 more source

Quantitative Expression of C-Type Lectin Receptors in Humans and Mice [PDF]

open access: yes, 2012
C-type lectin receptors, their adaptor molecules and S-type lectins (galectins) are involved in the recognition of glycosylated self-antigens and pathogens.
Akira   +39 more
core   +5 more sources

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