Results 131 to 140 of about 120,943 (337)
Compared with those on the pTi surface, macrophages on the TNTs surface present reduced myosin II contractility, which facilitates the nuclear translocation of the UTX. This reduction decreases the enrichment of the repressive H3K27me3 histone modification at the Abca1 gene locus, which promotes the transcription and protein expression of ABCA1 ...
Hengji Jia+8 more
wiley +1 more source
Clinical and pathological aspects and cerebellar lectin binding in cattle poisoned with Solanum fastigiatum var. fastigiatum and Solanum bonariense [PDF]
Microscopic and lectin histochemical studies were performed using the cerebella of 33 natural cases of Solanum fastigiatum var. fastigiatum intoxication in the cattle from southern Brazil and 2 natural and 4 experimental cases of Solanum bonariense from ...
Barbeito, Claudio Gustavo+6 more
core
Alteration of the Specificity of Lectin by Chemical Modification [PDF]
Shoji Matsubara, William C. Boyd
openalex +1 more source
In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang+6 more
wiley +1 more source
Objectives Rapid advances in transcriptomics have driven efforts to identify deregulated pathways in multiple sclerosis (MS) tissues, though many detected differentially expressed genes are likely false positives, with only a small fraction reflecting actual pathological events. Robust, integrative methods are essential for accurately understanding the
Gianmarco Abbadessa+11 more
wiley +1 more source
Letter to the Editor: LO2, a misidentified cell line: Some data should be interpreted with caution
Hepatology, EarlyView.
Ralf Weiskirchen
wiley +1 more source
Network Analysis Reveals the Recognition Mechanism for Dimer Formation of Bulb-type Lectins
The bulb-type lectins are proteins consist of three sequential beta-sheet subdomains that bind to specific carbohydrates to perform certain biological functions.
Yunjie Zhao+9 more
doaj +1 more source
Chemically modified graphene oxide nanocarriers provide a targeted lung cancer gene therapy platform. In a 3D tumor microenvironment model, these nanocarriers deliver therapeutic genes, regulate immune markers, and induce apoptosis in cancer cells. Combined gene delivery enhances cancer cell elimination, demonstrating the potential of this approach for
Francesca Grilli+3 more
wiley +1 more source
Quantitative Analysis of Fluorescent Sensor Arrays
Fluorescent sensor arrays address the limitations of a single sensor by leveraging multiple sensing elements to generate unique response patterns for each of the analyte of interest. This approach has emerged as a powerful tool for identifying and analysing intricate chemical and biological environments using various multivariate analytical tools such ...
Karandeep Grover+3 more
wiley +1 more source
Objective Genetic associations and blockade of the interleukin (IL)‐23/IL‐17 axis with monoclonal antibodies support a role for this pathway in patients with psoriatic arthritis (PsA). This study examines the requirement of IL‐23 for IL‐17 production and the role of the metabolic microenvironment in the expansion of Th17‐derived cells in patients with ...
Carmel B. Stober+4 more
wiley +1 more source