Results 101 to 110 of about 10,337 (219)

Comparative study of the ability of Leishmania mexicana promastigotes and amastigotes to alter macrophage signalling and functions

open access: yes, 2010
Leishmania alternates between two morphologically different stages: promastigotes and amastigotes. While the majority of reports focused on how the promastigote form can alter macrophage signalling and function, fewer reports investigated signalling ...
Hassani, K.   +9 more
core   +1 more source

Cell migration induced by Leishmania (Leishmania) amazonensis, Leishmania (Leishmania) major and Leishmania (Viannia) braziliensis into the peritoneal cavity of BALB/c mice

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2010
In American cutaneous leishmaniasis, the initial infection phase is characterized by recruitment of neutrophils and monocytes. The migration of these cells in response to the presence of Leishmania in the peritoneum of affected animals remains unclear ...
DT Wakimoto   +4 more
doaj   +1 more source

Studies on immunology of Leishmania mexicana

open access: yes, 2007
Leishmaniasis is a worldwide disease prevalent in many tropical and sub tropical countries. Treatment of Leishmaniasis by chemotherapy is not wholly effective and is usually accompanied by unpleasant side effects.
Rezvan, H, Rezvan, Hossein
core  

Impacto del volumen del fagosoma en los niveles de ARNm de IL-12 en infección por Leishmania amazonensis [PDF]

open access: yes, 2015
La interacción entre macrófago y patógeno es la responsable de modular la respuesta adaptativa mediada por linfocitos T como células efectoras. En la infección por Leishmania se ha establecido una clara relación entre la secreción de citoquinas pro ...
Heredia Campos, Ivett Julieth
core  

Activity of anti-cancer protein kinase inhibitors against Leishmania spp.

open access: yes, 2014
OBJECTIVES: There is an urgent need to develop new and effective treatments for poverty-related neglected diseases. In light of the time required to bring a new drug to market and the cost involved (10-15 years, >1 billion US$), one approach to ...
Croft, Simon L   +2 more
core   +1 more source

Comparative two-dimensional gel electrophoresis maps for promastigotes of Leishmania amazonensis and Leishmania major

open access: yesBrazilian Journal of Infectious Diseases
The outcome of Leishmania infections is determined by both the parasite species and the host genetic makeup. While much has been learned regarding immune responses to this parasite, our knowledge on parasite-derived factors is limited.
Reynolds K. B. Brobey   +3 more
doaj   +1 more source

CENTRAL NERVOUS SYSTEM INVOLVEMENT IN EXPERIMENTAL INFECTION WITH LEISHMANIA (LEISHMANIA) AMAZONENSIS

open access: yesThe American Journal of Tropical Medicine and Hygiene, 2003
We describe the pathologic alterations of the central nervous system (CNS) observed in experimental tegumentary leishmaniasis in BALB/c and Swiss mice. The mice were subcutaneously infected with 104 amastigotes of Leishmania (Leishmania) amazonensis. Animals were killed and brains were removed for histologic and immunocytochemical studies.
Abreu-Silva, Ana Lucia   +4 more
openaire   +2 more sources

Immunogold labeling and cerium cytochemistry of the enzyme ecto-5'-nucleotidase in promastigote forms of Leishmania species

open access: yesMemorias do Instituto Oswaldo Cruz, 1993
We have applied both enzyme cytochemistry and immunological labeling techniques to characterize the enzyme 5'-nucleotidase (5'-Nase), at the ultrastructural level, in promastigote forms of four Leishmania species: Leishmania amazonensis, Leishmania ...
Suzana Corte-Real   +2 more
doaj   +1 more source

Verbascoside Inhibits Promastigote Growth and Arginase Activity of Leishmania amazonensis [PDF]

open access: yes, 2016
Verbascoside (1) is a phenylethanoid glycoside that has antileishmanial activity against Leishmania infantum and Leishmania donovani. In this study, we verified the activity of 1 on Leishmania amazonensis and arginase inhibition.
Brogi S.   +13 more
core   +1 more source

Eco-epidemiological aspects, natural detection and molecular identification of Leishmania spp. in Lutzomyia reburra, Lutzomyia barrettoi majuscula and Lutzomyia trapidoi

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2017
Introduction: The province of Pichincha in Ecuador is an endemic area of cutaneous leishmaniasis, where anthropophilic sand flies with natural infection by Leishmania, have been reported as vectors.
Jazzmín Arrivillaga-Henríquez   +8 more
doaj   +1 more source

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