The use of kDNA minicircle subclass relative abundance to differentiate between Leishmania (L.) infantum and Leishmania (L.) amazonensis [PDF]
Parasites & Vectors, 2017 Background Leishmaniasis is a neglected disease caused by many Leishmania species, belonging to subgenera Leishmania (Leishmania) and Leishmania (Viannia).
Marcello Ceccarelli +7 more
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In vitro and in vivo activity of a palladacycle complex on Leishmania (Leishmania) amazonensis. [PDF]
PLoS Neglected Tropical Diseases, 2012 BACKGROUND: Antitumor cyclopalladated complexes with low toxicity to laboratory animals have shown leishmanicidal effect. These findings stimulated us to test the leishmanicidal property of one palladacycle compound called DPPE 1.2 on Leishmania ...
Carolina de Siqueira Paladi +6 more
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Autophagic Induction Greatly Enhances Leishmania major Intracellular Survival Compared to Leishmania amazonensis in CBA/j-Infected Macrophages [PDF]
Frontiers in Microbiology, 2018 CBA mouse macrophages control Leishmania major infection yet are permissive to Leishmania amazonensis. Few studies have been conducted to assess the role played by autophagy in Leishmania infection.
Beatriz R. S. Dias +11 more
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Non-canonical NLRP3 inflammasome activation and IL-1β signaling are necessary to L. amazonensis control mediated by P2X7 receptor and leukotriene B4. [PDF]
PLoS Pathogens, 2019 Leishmaniasis is a neglected tropical disease affecting millions of individuals worldwide. P2X7 receptor has been linked to the elimination of Leishmania amazonensis.
Mariana M Chaves +9 more
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Surface enolase is a virulence factor of Leishmania amazonensis metacyclic promastigotes involved in adhesion to macrophages [PDF]
Frontiers in MicrobiologyWe find that enolase, an evolutionarily conserved and multifunctional protein, is displayed on the cell surface of Leishmania amazonensis parasites in a developmentally regulated manner, associated with infectivity.
Franciane dos Santos Alves +7 more
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Frontiers in Immunology, 2023 In this study we explored the previously established leishmanicidal activity of a complementary set of 24 imidazolium salts (IS), 1-hexadecylimidazole (C16Im) and 1-hexadecylpyridinium chloride (C16PyrCl) against Leishmania (Leishmania) amazonensis and ...
Fernanda Giesel Baldissera +20 more
doaj +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2022 Background: American tegumentary leishmaniasis is a parasitic disease known for being difficult to treat; therefore, the search for more effective therapeutic methods is necessary.
Pauline de Faria Soldera +5 more
doaj +1 more source
Experimental infection and transmission of Leishmania by Lutzomyia cruzi (Diptera: Psychodidae): Aspects of the ecology of parasite-vector interactions. [PDF]
PLoS Neglected Tropical Diseases, 2017 Several parameters should be addressed before incriminating a vector for Leishmania transmission. Those may include its ability to become infected by the same Leishmania species found in humans, the degree of attractiveness for reservoirs and humans and ...
Everton Falcão de Oliveira +7 more
doaj +1 more source
Microorganisms, 2020 Leishmania protozoa are the etiological agents of visceral, cutaneous and mucocutaneous leishmaniasis. In specific geographical regions, such as Latin America, several Leishmania species are endemic and simultaneously present; therefore, a diagnostic ...
Marcello Ceccarelli +9 more
doaj +1 more source
The diverse and dynamic nature of Leishmania parasitophorous vacuoles studied by multidimensional imaging. [PDF]
PLoS Neglected Tropical Diseases, 2012 An important area in the cell biology of intracellular parasitism is the customization of parasitophorous vacuoles (PVs) by prokaryotic or eukaryotic intracellular microorganisms.
Fernando Real, Renato A Mortara
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