Results 11 to 20 of about 13,174,260 (209)
Sphingolipid degradation in Leishmania (Leishmania) amazonensis.
PLoS Neglected Tropical Diseases, 2012 BackgroundHuman leishmaniasis is caused by more than 20 Leishmania species and has a wide range of symptoms. Our recent studies have demonstrated the essential role of sphingolipid degradation in the virulence of Leishmania (Leishmania) major, a species ...
Agiesh Balakrishna Pillai +3 more
doaj +2 more sources
Analysis and chromosomal mapping of Leishmania (Leishmania) amazonensis amastigote expressed sequence tags [PDF]
Memorias do Instituto Oswaldo Cruz, 2007 The characterization of expressed sequence tags (ESTs) generated from a cDNA library of Leishmania (Leishmania) amazonensis amastigotes is described. The sequencing of 93 clones generated new L. (L.) amazonensis ESTs from which 32% are not related to any
Luciana Girotto Gentil +4 more
doaj +2 more sources
Differential regulation of dendritic cells migration after L. major and L. amazonensis infection [PDF]
, 2018 Leishmaniasis is an endemic disease in tropical and subtropical regions of the world, where it is mainly manifested within mammals. This zoonotic disease is caused by an infection with a protozoan parasite called Leishmania, which resides within the mammal’s macrophages and/or dendritic cells.
Soto-Ruiz, Víctor
openaire +3 more sources
Neutrophils reduce the parasite burden in Leishmania (Leishmania) amazonensis-infected macrophages. [PDF]
PLoS ONE, 2010 BackgroundStudies on the role of neutrophils in Leishmania infection were mainly performed with L. (L) major, whereas less information is available for L. (L) amazonensis.
Erico Vinícius de Souza Carmo +2 more
doaj +2 more sources
International Journal for Parasitology, 2003 The present study describes the cloning and characterisation of a gene encoding a cysteine proteinase isoform, Llacys1, expressed in amastigote forms of Leishmania (L.) amazonensis. Recombinant clones containing the Llacys1 gene were isolated from genomic DNA by PCR amplification and screening of an amastigote cDNA library.
Fernanda, Lasakosvitsch +4 more
openaire +3 more sources
Parasites & Vectors, 2017 Background Interleukin 32 (IL-32) is a pro-inflammatory cytokine induced in patients with American tegumentary leishmaniasis (ATL) caused by Leishmania braziliensis.
Rodrigo Saar Gomes +11 more
doaj +3 more sources
Atividade de álcool, aldeído e ácido perílico contra L. (L.) major e L. (L.) amazonensis. [PDF]
, 2015 Propriedades leishmanicidas têm sido atribuídas a vários terpenos, que são compostos encontrados em plantas. Dentre esses está o limoneno, um monoterpeno presente principalmente em frutas cítricas.
Aedo, Jenny Rosario Niño de Guzman +1 more
openaire +2 more sources
Metabolomic Reprogramming of C57BL/6-Macrophages during Early Infection with L. amazonensis. [PDF]
Int J Mol Sci, 2021 Leishmania survival inside macrophages depends on factors that lead to the immune response evasion during the infection. In this context, the metabolic scenario of the host cell–parasite relationship can be crucial to understanding how this parasite can survive inside host cells due to the host’s metabolic pathways reprogramming. In this work, we aimed
Mamani-Huanca M +5 more
europepmc +4 more sources
Leishmania (L.) amazonensis LaLRR17 increases parasite entry in macrophage by a mechanism dependent on GRP78. [PDF]
Parasitology, 2023 AbstractLeishmaniases affect 12 million people worldwide. They are caused by Leishmania spp., protozoan parasites transmitted to mammals by female phlebotomine flies. During the life cycle, promastigote forms of the parasite live in the gut of infected sandflies and convert into amastigotes inside the vertebrate macrophages.
Peña MS +10 more
europepmc +4 more sources
Comparing the Antileishmanial Activity of Gold(I) and Gold(III) Compounds in L. amazonensis and L. braziliensis in Vitro. [PDF]
ChemMedChem, 2020 AbstractAbstract: A series of mononuclear coordination or organometallic AuI/AuIII complexes (1–9) have been comparatively studied in vitro for their antileishmanial activity against promastigotes and amastigotes, the clinically relevant parasite form, of Leishmania amazonensis and Leishmania braziliensis.
Minori K +4 more
europepmc +5 more sources