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Detection of Leishmania (Leishmania) amazonensis and Leishmania (Leishmania) infantum chagasi in Brazilian bats

Veterinary Parasitology, 2010
Although bats are one of the most abundant mammals in the new world and are present in virtually all ecosystems, including urban and peri-urban environments, few studies have investigated the role of these animals in the epidemiological chain of leishmaniosis.
Elisa San Martin Mouriz, Savani   +6 more
openaire   +2 more sources

Leishmania (Viannia) panamensis/Leishmania (Leishmania) amazonensis—A Warning

Parasitology Today, 1999
The parasite Leishmania (Viannia) panamensis causes local cutaneous lesions. The Laboratory of Infectious Disease Pathology of the University of Sao Paulo Medical School has been working with a strain of Leishmania (Viannia) panamensis, HSJD-1, characterized by isoenzyme at the Liverpool School of Tropical Medicine, by W.
openaire   +2 more sources

Antileishmanial Activity of Azitahromycin Against Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis, and Leishmania (Leishmania) chagasi

The American Journal of Tropical Medicine and Hygiene, 2008
Azithromycin, an azalide antibiotic, is highly concentrated within different phagocytic cells, especially macrophages. The potential antileishmanial activity of azithromycin against three species of Leishmania from the New World was assessed using in vitro models.
Fernanda, de Oliveira-Silva   +2 more
openaire   +2 more sources

Immunological characteristics of experimental murine infection with Leishmania (Leishmania) amazonensis

Veterinary Parasitology, 2008
The murine models of Leishmania infection are well-studied and suitable models for studying this disease, which, despite its incidence of nearly 2 million new cases worldwide per year and its prevalence of 12 million cases, has been a somewhat neglected disease.
Bernardo Acácio Santini, Pereira   +1 more
openaire   +2 more sources

Eosinophil chemotactic activity in Leishmania amazonensis promastigotes

Parasitology Research, 1996
Tissue eosinophilia was observed in the subcutaneous tissue of mice shortly after their inoculation not only with living but also with lysed promastigotes of Leishmania amazonensis. Intraperitoneal inoculation of lysed promastigotes from five different Leishmania species (L. donovani, L. chagasi, L. tropica, L. amazonensis, and L. braziliensis) induced
S, Saito   +5 more
openaire   +2 more sources

Apparent isocitrate lyase activity in Leishmania amazonensis

Acta Parasitologica, 2017
AbstractEarly reports have demonstrated the occurrence of glyoxylate cycle enzymes in ...
Concepción, Hernández-Chinea   +4 more
openaire   +2 more sources

Genomic organization of telomeric and subtelomeric sequences of Leishmania (Leishmania) amazonensis

International Journal for Parasitology, 2005
Telomeres are DNA-protein complexes that protect linear chromosomes from degradation and fusions. Telomeric DNA is repetitive and G-rich, and protrudes towards the end of the chromosomes as 3'G-overhangs. In Leishmania spp., sequences adjacent to telomeres comprise the Leishmania conserved telomere associated sequences (LCTAS) that are around 100 bp ...
F F, Conte, M I N, Cano
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Tetroxanes as New Agents against Leishmania amazonensis

Chemistry & Biodiversity, 2020
AbstractLeishmaniasis is a neglected disease, caused by a parasite of Leishmania genus and widespread in the tropical and subtropical areas of the world. Currents drugs are limited due to their toxicity and parasite resistance. Therefore, the discovery of new treatment, more effective and less toxic, is urgent. In this study, we report the synthesis of
Isabel V. Antolínez   +6 more
openaire   +2 more sources

Histopathological studies of visceralized Leishmania (Leishmania) amazonensis in mice experimentally infected

Veterinary Parasitology, 2004
BALB/c, C57BL/6, and DBA/2 mice were subcutaneously infected in the left footpad by injecting 10(4) Leishmania (Leishmania) amazonensis amastigotes. Mice were sacrificed 20, 30, 40, 60 and 90 days post-infection. Fragments of liver, kidney, spleen, skin, and draining lymph node were collected for histological examination.
A L, Abreu-Silva   +5 more
openaire   +2 more sources

Active Transport of Glutamate in Leishmania (Leishmania) amazonensis

Journal of Eukaryotic Microbiology, 2008
ABSTRACT. Leishmania spp. are the causative agents of leishmaniasis, a complex of diseases with a broad spectrum of clinical manifestations. Leishmania (Leishmania) amazonensis is a main etiological agent of diffuse cutaneous leishmaniasis. Leishmania spp., as other trypanosomatids, possess a metabolism based significantly on the consumption of amino
Lisvane S, Paes   +5 more
openaire   +2 more sources

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