Results 61 to 70 of about 11,235 (212)

Evaluation of the Cutaneous Immunological Milieu Before and After Treatment With Meglumine Antimoniate in Dogs Naturally Affected by Leishmaniosis due to Leishmania infantum

Veterinary Dermatology, EarlyView.
Background: Canine leishmaniosis (CanL) is a zoonotic disease of variable severity. The typical immune response is driven by an exaggerated humoral immune response. Protective immunity is mediated by pro‐inflammatory cytokines that enhance macrophage leishmanicidal activity. Objective: To evaluate the cutaneous and the systemic immune responses as well
M. Platenik, A. Di Loria, L. Archer, M. Saridomichelakis, A. S. Benvenuto, D. Santoro   +5 more
wiley   +1 more source

Infectiousness in a Cohort of Brazilian Dogs: Why Culling Fails to Control Visceral Leishmaniasis in Areas of High Transmission [PDF]

, 2002
The elimination of seropositive dogs in Brazil has been used to control zoonotic visceral leishmaniasis but with little success. To elucidate the reasons for this, the infectiousness of 50 sentinel dogs exposed to natural Leishmania chagasi infection was
Courtenay, O., Dye, C., Garcez, L.M., Quinnell, R.J., Shaw, J.J.   +4 more
core  

Leishmania chagasi heparin-binding protein: Cell localization and participation in L. chagasi infection

Molecular and Biochemical Parasitology, 2015
Visceral leishmaniasis is a fatal human disease caused by the intracellular protozoan parasite Leishmania chagasi that is captured by host cells in a process involving classics receptors mediated phagocytosis. The search for molecules involved in this process is important to design strategies to disease control.
Thaís Viana Fialho, Martins, Thaís Vieira, de Carvalho, Claudia Vânia Miranda, de Oliveira, Sérgio Oliveira, de Paula, Sílvia Almeida, Cardoso, Leandro Licursi, de Oliveira, Eduardo de Almeida, Marques-da-Silva   +6 more
openaire   +3 more sources

Factors Associated With the Emergence and Spread of Visceral Leishmaniasis in the State of São Paulo, Brazil

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Visceral leishmaniasis (VL), once considered a rural disease in Brazil, has progressively urbanised, particularly in the state of São Paulo (SSP), where the first urban cases emerged after the detection of the vector Lutzomyia longipalpis in 1997.
Vera Lucia Fonseca de Camargo‐Neves, Guilherme Loureiro Werneck   +1 more
wiley   +1 more source

A prime/boost DNA/Modified vaccinia virus Ankara vaccine expressing recombinant Leishmania DNA encoding TRYP is safe and immunogenic in outbred dogs, the reservoir of zoonotic visceral leishmaniasis [PDF]

Previous studies demonstrated safety, immunogenicity and efficacy of DNA/modified vaccinia virus Ankara (MVA) prime/boost vaccines expressing tryparedoxin peroxidase (TRYP) and Leishmania homologue of the mammalian receptor for activated C kinase (LACK ...
Alcami, Antonio, Antoniou, Maria, Begoña Ruiz-Argüello, Maria, Blackwell, Jenefer M., Carson, Connor, Christodoulou, Vasiliki, Courtenay, Orin, Messaritakis, Ippokratis   +7 more
core   +1 more source

Anti-leishmania antibodies in cerebrospinal fluid from dogs with visceral leishmaniasis

Brazilian Journal of Medical and Biological Research, 2003
Visceral leishmaniasis in Brazil is caused by Leishmania (Leishmania) chagasi and the dog is its most important reservoir. The clinical features in dogs include loss of weight, lymphadenopathy, renal failure, skin lesions, fever, hypergammaglobulinemia ...
V.M.F. Lima, M.E. Gonçalves, F.A. Ikeda, M.C.R. Luvizotto, M.M. Feitosa   +4 more
doaj   +1 more source

Immunogold labeling and cerium cytochemistry of the enzyme ecto-5'-nucleotidase in promastigote forms of Leishmania species

Memorias do Instituto Oswaldo Cruz, 1993
We have applied both enzyme cytochemistry and immunological labeling techniques to characterize the enzyme 5'-nucleotidase (5'-Nase), at the ultrastructural level, in promastigote forms of four Leishmania species: Leishmania amazonensis, Leishmania ...
Suzana Corte-Real, Renato Porrozzi, Maria de Nazareth Leal de Meirelles   +2 more
doaj   +1 more source

Resistance of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensisto nitric oxide correlates with disease severity in Tegumentary Leishmaniasis [PDF]

, 2007
Background Nitric oxide (NO•) plays a pivotal role as a leishmanicidal agent in mouse macrophages. NO• resistant Escherichia coli and Mycobacterium tuberculosis have been associated with a severe outcome of these diseases.
Angela Giudice, Ilza Camada, Paulo TG Leopoldo, Júlia MB Pereira, Lee W Riley, Mary E Wilson, John L Ho, Amelia Ribeiro de Jesus, Edgar M Carvalho, Roque P Almeida, AL Bittencourt, H Louzir, M Castes, PD Marsden, JM Costa, J Alexander, J Alexander, FY Liew, P Scott, ME Wilson, FY Liew, FY Liew, C Bogdan, SJ Green, TG Evans, J Assreuy, HW Murray, S Nicholson, KR Gantt, C Bogdan, J Mauel, PR Romao, WJ Paramchuk, SR Meshnick, TJ Vickers, MP Levick, MA Miller, FC Fang, E Cupolillo, ME Wilson, C Bogdan, HW Murray, NE Reiner, P Scott, I Vouldoukis, P Kumar, C Bogdan, M Barral-Netto, ME Wilson, E Cupolillo, SM Cupolilo, A Schriefer, KA Rockett, I Vouldoukis, NK Basu, M Genestra, M Genestra, R Hanano, K Kawakami, DR Pakianathan, FM Balestieri, A Descoteaux, C Nathan, A Jardim   +63 more
core   +1 more source

Lulo cell line derived from Lutzomyia longipalpis (Diptera: Psychodidae): a novel model to assay Leishmania spp. and vector interaction

Parasites & Vectors, 2011
Background Leishmania (Vianna) braziliensis, Leishmania (Leishmania) amazonensis and Leishmania (Leishmania) chagasi are important parasites in the scenario of leishmaniasis in Brazil.
Côrtes Luzia MC, Silva Roger MM, Pereira Bernardo AS, Guerra Camila, Zapata Angela C, Bello Felio J, Finkelstein Léa C, Madeira Maria F, Brazil Reginaldo P, Côrte-Real Suzana, Alves Carlos R   +10 more
doaj   +1 more source

Sex in Immune Cells and Parasitic Diseases — A Complex Relationship

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker, Charlotte Sophie Hansen, Hanna Lotter   +2 more
wiley   +1 more source