Results 111 to 120 of about 34,168 (257)

l-Arginine Uptake by Cationic Amino Acid Transporter Promotes Intra-Macrophage Survival of Leishmania donovani by Enhancing Arginase-Mediated Polyamine Synthesis

open access: yesFrontiers in Immunology, 2017
The survival of intracellular protozoan parasite, Leishmania donovani, the causative agent of Indian visceral leishmaniasis (VL), depends on the activation status of macrophages. l-Arginine, a semi-essential amino acid plays a crucial regulatory role for
Abhishek Mandal   +14 more
doaj   +1 more source

A neglected disease of humans: a new focus of visceral leishmaniasis in Bakool, Somalia. [PDF]

open access: yes, 2008
Visceral leishmaniasis (VL) was observed in children in Bakool region, Somalia, an area where VL has not been reported before. We describe the extent of the problem in this war- and famine-stricken area.
Boelaert, M   +5 more
core   +1 more source

An arginine deprivation response pathway is induced in Leishmania during macrophage invasion [PDF]

open access: yes, 2016
Amino acid sensing is an intracellular function that supports nutrient homeostasis, largely through controlled release of amino acids from lysosomal pools.
Balno, Caitlin   +10 more
core   +3 more sources

A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodes [PDF]

open access: yes, 2014
Myristoylation is a lipid modification involving the addition of a 14-carbon unsaturated fatty acid, myristic acid, to the N-terminal glycine of a subset of proteins, a modification that promotes their binding to cell membranes for varied biological ...
Carlow, Clotilde K. S.   +7 more
core   +3 more sources

Neutrophil responses to CRP are not dependent on polymorphism of human FcgammaRIIA (R131H).

open access: yes, 2004
IgG2a mediated in vitro phagocytosis is less effective for individuals homozygous for Fcgamma RIIaR131 allele and such individuals are also more susceptible to certain infections.
Bodman-Smith, KB   +2 more
core   +2 more sources

A cyclic nucleotide-independent protein kinase in Leishmania donovani [PDF]

open access: green, 1986
Siddhartha Das   +3 more
openalex   +1 more source

Physiological Age Structure and Leishmania spp. Detection in Phlebotomus (Larroussius) orientalis (Parrot, 1936) (Diptera: Psychodidae) at an Endemic Focus of Visceral Leishmaniasis in Northern Ethiopia

open access: yesJournal of Tropical Medicine, 2015
Visceral leishmaniasis (VL) caused by Leishmania donovani is endemic in northern Ethiopia, where P. orientalis is the most important presumed vector. This study was designed to determine the physiological age structure and the occurrence of Leishmania ...
Araya Gebresilassie   +9 more
doaj   +1 more source

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