Results 61 to 69 of about 1,239 (69)

Current Perspectives on Leishmaniasis

Journal of Gandaki Medical College, 2019
No abstract available.
KR Reddy
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Can cutaneous leishmaniasis provoke a resurgence of kala-azar in the Indian subcontinent?

BMC Infectious Diseases
Background The ongoing kala-azar elimination program in Nepal is based on the assumption of anthroponotic transmission of the protozoan parasite Leishmania donovani. This parasite species was recently also found in lesions of cutaneous leishmaniasis (CL)
Narayan Raj Bhattarai, Keshav Rai, Surendra Uranw, Dhan Keshar Khadka, Basudha Khanal, Gokarna Dahal, Sushmita Pradhan, Sushil Dhakal, Pieter Monsieurs, Tanyth de Gooyer, Kristien Cloots, Epco Hasker, Gert Van der Auwera   +12 more
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Comparative study of the biological behaviour in hamster of two isolates of leishmania characterized respectively as L. major-like and L. donovani

Revista do Instituto de Medicina Tropical de São Paulo, 1988
Hamster inoculated intraperitoneally with 1 x 10(7) parasites of L. donovani and L. major-like of the New World were studied in groups of 15, 30, 60 and 90 days of infection. The parasite load and density showed progressive increase with the evolution of
M. I. S. Duarte, M. D. Laurenti, H. F. Andrade Jr., C. E. P. Corbett   +3 more
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Effective Tetradentate Compound Complexes against Leishmania spp. that Act on Critical Enzymatic Pathways of These Parasites

Molecules, 2018
The spectrum and efficacy of available antileishmanial drugs is limited. In the present work we evaluated in vitro the antiproliferative activity of 11 compounds based on tetradentate polyamines compounds against three Leishmania species (L. braziliensis,
Kristína Urbanová, Inmaculada Ramírez-Macías, Rubén Martín-Escolano, María José Rosales, Olaf Cussó, Joan Serrano, Anna Company, Manuel Sánchez-Moreno, Miquel Costas, Xavi Ribas, Clotilde Marín   +10 more
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Emerging Leishmania donovani Lineages Associated with Cutaneous Leishmaniasis, Himachal Pradesh, India, 2023

Emerging Infectious Diseases
The clinical manifestation of leishmaniasis has historically been determined by the Leishmania species involved. However, recent emergence of novel Leishmania lineages has caused atypical pathologies.
Patrick Lypaczewski, Yogesh Chauhan, Kayla Paulini, Lovlesh Thakur, Shailja Chauhan, Ezrah Isaac Roy, Greg Matlashewski, Manju Jain   +7 more
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l-Arginine Uptake by Cationic Amino Acid Transporter Promotes Intra-Macrophage Survival of Leishmania donovani by Enhancing Arginase-Mediated Polyamine Synthesis

Frontiers in Immunology, 2017
The survival of intracellular protozoan parasite, Leishmania donovani, the causative agent of Indian visceral leishmaniasis (VL), depends on the activation status of macrophages. l-Arginine, a semi-essential amino acid plays a crucial regulatory role for
Abhishek Mandal, Sushmita Das, Ajay Kumar, Saptarshi Roy, Sudha Verma, Ayan Kumar Ghosh, Ruby Singh, Kumar Abhishek, Savita Saini, Savita Saini, Abul Hasan Sardar, Bidyut Purkait, Ashish Kumar, Chitra Mandal, Pradeep Das   +14 more
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Physiological Age Structure and Leishmania spp. Detection in Phlebotomus (Larroussius) orientalis (Parrot, 1936) (Diptera: Psychodidae) at an Endemic Focus of Visceral Leishmaniasis in Northern Ethiopia

Journal of Tropical Medicine, 2015
Visceral leishmaniasis (VL) caused by Leishmania donovani is endemic in northern Ethiopia, where P. orientalis is the most important presumed vector. This study was designed to determine the physiological age structure and the occurrence of Leishmania ...
Araya Gebresilassie, Ibrahim Abbasi, Oscar David Kirstein, Essayas Aklilu, Solomon Yared, Habte Tekie, Meshesha Balkew, Alon Warburg, Asrat Hailu, Teshome Gebre-Michael   +9 more
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A Systematic Assessment of Leishmania donovani Infection in Domestic and Wild Animal Reservoir Hosts of Zoonotic Visceral Leishmaniasis in India

Microbiology Research
Leishmaniasis is a neglected disease with a global spread that affects both domestic and wild animals in addition to people. Leishmania donovani is the suspected anthroponotic cause of visceral leishmaniasis (VL) in India, where it is an endemic disease.
Gajala Deethamvali Ghouse Peer, Anjali Priyadarshini, Archana Gupta, Arpana Vibhuti, Elcio Leal, Antonio Charlys da Costa, Carlos Prudencio, Kirtanjot Kaur, Saheem Ahmad, V. Samuel Raj, Ramendra Pati Pandey   +10 more
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Induction of apoptosis by zerumbone isolated from Zingiber zerumbet (L.) Smith in protozoan parasite Leishmania donovani due to oxidative stress

Brazilian Journal of Infectious Diseases, 2016
In the present context of emergence of resistance aligned with the conventional anti-leishmanial drugs and occasional treatment failure compelled us to continue the search for replaceable therapeutic leads against Leishmania infection.
Debarati Mukherjee, Chingakham Brajakishor Singh, Somaditya Dey, Supratim Mandal, Joydip Ghosh, Suvadip Mallick, Aabid Hussain, Ningombam Swapana, Samir Anis Ross, Chiranjib Pal   +9 more
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