Results 71 to 80 of about 29,719 (208)
The first detection of Leishmania major in naturally infected Sergentomyia minuta in Portugal [PDF]
, 2013 Phlebotomine sandflies of the genus Sergentomyia are widely distributed throughout the Old World. It has been suggested that Sergentomyia spp are involved in the transmission of Leishmania in India and Africa, whereas Phlebotomus spp are thought to be ...
Afonso, Maria Odete +5 more
core +3 more sources
Exploring Aspartate Transcarbamoylase: A Promising Broad‐Spectrum Target for Drug Development
ChemBioChem, Volume 26, Issue 7, April 1, 2025.Pyrimidine biosynthesis is a pivotal process shared by both eukaryotes and prokaryotes. This review examines the applications and advantages of a series of inhibitors specifically designed to target aspartate transcarbamylase within the de novo biosynthetic pathway of the malarial parasite.
Siyao Chen +8 more
wiley +1 more source
The effect of Marigold flower extracts on growth of Leishmania. [PDF]
Kirkuk Journal of Science, 2018 This study searched in the inhibiting potency of different concentrations (12.5, 25, 50 and 100 µg/mL) of both aqueous and methanol extracts of marigold plant flower Calendula officinalis against the promastigote of Leismania major, L. donovani and
Neama Ali Ahmad
doaj +1 more source
Frontiers in Public Health, 2023 BackgroundVisceral leishmaniasis (VL) is a neglected vector-borne tropical disease caused by Leishmania donovani (L. donovani) and Leishmania infantum (L. infantum).
Li Chang +15 more
doaj +1 more source
The FEBS Journal, Volume 292, Issue 8, Page 1868-1883, April 2025.Traditionally, adipocytes have been viewed as energy storage units, which upregulate inflammatory factors in response to obesity. However, emerging evidence demonstrates that adipocytes are highly responsive to systemic infection, and upregulate cytokines and antimicrobial compounds in response.
Matthew C. Sinton, Shingo Kajimura
wiley +1 more source
PLoS ONE, 2016 Visceral leishmaniasis (VL) is a debilitating, often fatal disease caused by Leishmania donovani complex; however, it is a neglected tropical disease. L. donovani complex comprises two closely related species, L. donovani that is mostly anthroponotic and
Mohammed A K Mahdy +7 more
doaj +1 more source
Sphingosine-1-phosphate signaling in Leishmania donovani infection in macrophages. [PDF]
PLoS Neglected Tropical Diseases, 2018 BACKGROUND:Sphingosine-1-phosphate (S1P) is a crucial regulator of a wide array of cellular processes, such as apoptosis, cell proliferation, migration, and differentiation, but its role in Leishmania donovani infection is unknown. METHODOLOGY/ PRINCIPAL
Mohd Arish +6 more
doaj +1 more source
Diabetes, Obesity and Metabolism, Volume 27, Issue 3, Page 1045-1064, March 2025.Abstract Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by T cell‐mediated pancreatic β cell loss, resulting in lifelong absolute insulin deficiency and hyperglycaemia. Environmental factors are recognized as a key contributor to the development of T1D, with the gut serving as a primary interface for environmental stimuli.
Ruonan Liu +6 more
wiley +1 more source
Global genome diversity of the Leishmania donovani complex
eLife, 2020 Protozoan parasites of the Leishmania donovani complex – L. donovani and L. infantum – cause the fatal disease visceral leishmaniasis. We present the first comprehensive genome-wide global study, with 151 cultured field isolates representing most of the ...
Susanne U Franssen +20 more
doaj +1 more source
Fungal Biomolecules for Food and Pharmaceutical Application
eFood, Volume 6, Issue 1, February 2025.The review summarizes the diverse roles of fungal biomolecules in the food and pharmaceutical industries and highlights their significant contribution to modern medicine and health‐related fields. ABSTRACT Mushrooms have long been an integral part of human culture and health and are valued for their nutritional and therapeutic properties.
Giancarlo Angeles Flores +4 more
wiley +1 more source