Results 71 to 80 of about 78,367 (315)

Binding of Leishmania infantum Lipophosphoglycan to the Midgut Is Not Sufficient To Define Vector Competence in Lutzomyia longipalpis Sand Flies

mSphere, 2020
The major surface lipophosphoglycan (LPG) of Leishmania parasites is critical to vector competence in restrictive sand fly vectors in mediating Leishmania attachment to the midgut epithelium, considered essential to parasite survival and development ...
Iliano V. Coutinho-Abreu, James Oristian, Waldionê de Castro, Timothy R. Wilson, Claudio Meneses, Rodrigo P. Soares, Valéria M. Borges, Albert Descoteaux, Shaden Kamhawi, Jesus G. Valenzuela   +9 more
doaj   +1 more source

First Detection and Molecular Analysis of Leishmania infantum DNA in Sand Flies of Kosovo

Pathogens, 2023
Phlebotomine sand flies (Diptera: Psychodidae) are the principal vectors of phleboviruses and Leishmania spp., the causative agents of leishmaniases. The Mediterranean sand fly fauna is diverse, and leishmaniasis, mainly caused by Leishmania infantum, is
Betim Xhekaj, Ina Hoxha, Katharina Platzgummer, Edwin Kniha, Julia Walochnik, Kurtesh Sherifi, Agim Rexhepi, Behlul Behluli, Vit Dvořák, Hans-Peter Fuehrer, Adelheid G. Obwaller, Wolfgang Poeppl, Jovana Stefanovska, Aleksandar Cvetkovikj   +13 more
doaj   +1 more source

Rapid Detection of Leishmania infantum Infection in Dogs: Comparative Study Using an Immunochromatographic Dipstick Test, Enzyme-Linked Immunosorbent Assay, and PCR [PDF]

, 2002
Current zoonotic visceral leishmaniasis (ZVL) control programs in Brazil include the culling of Leishmania infantum-infected reservoir dogs, a strategy that has failed to prevent a rise of canine and human ZVL cases over the past decade.
Bruce Alex, Bruce Alex, Clive R. Davies, Clive R. Davies, J. Clin Microbiol, Richard Reithinger, Richard Reithinger, Rupert J. Quinnell, Rupert J. Quinnell   +8 more
core   +3 more sources

Study of in vitro biological activity of thiazoles on Leishmania (Leishmania) infantum

Journal of Global Antimicrobial Resistance, 2020
In the prospection of possible agents against neglected diseases, thiazole compounds are presented as promising candidates and are known to have activity against trypanosomatid parasites. Thus, this work aimed to evaluate the effects of thiazole compounds on Leishmania infantum, the aetiological agent of visceral leishmaniasis.Thiazole compounds (five ...
Marcos Veríssimo de Oliveira Cardoso, Regina Celia Bressan Queiroz de Figueiredo, Valdemiro Amaro da Silva Junior, Mary Angela Aranda de Souza, Ana Cristina Lima Leite, Rafaela Ramos Mororó Cavalcanti, Vinícius Vasconcelos Gomes de Oliveira, Vinícius Vasconcelos Gomes de Oliveira   +7 more
openaire   +4 more sources

Prevalence of Leishmania species among patients with cutaneous leishmaniasis in Qassim province of Saudi Arabia

BMC Public Health, 2019
Background Leishmaniasis is a parasitic infection endemic in more than ninety countries of the world. The cutaneous leishmaniasis (CL) is a most common form of leishmaniasis and it remains to be a major public health issue in Saudi Arabia. This study was
Zafar Rasheed, Ahmed A. Ahmed, Tarek Salem, Mohammed S. Al-Dhubaibi, Ahmad A. Al Robaee, Abdullateef A. Alzolibani   +5 more
doaj   +1 more source

Experimental infection and transmission of Leishmania by Lutzomyia cruzi (Diptera: Psychodidae): Aspects of the ecology of parasite-vector interactions. [PDF]

PLoS Neglected Tropical Diseases, 2017
Several parameters should be addressed before incriminating a vector for Leishmania transmission. Those may include its ability to become infected by the same Leishmania species found in humans, the degree of attractiveness for reservoirs and humans and ...
Everton Falcão de Oliveira, Elisa Teruya Oshiro, Wagner de Souza Fernandes, Paula Guerra Murat, Márcio José de Medeiros, Alda Izabel Souza, Alessandra Gutierrez de Oliveira, Eunice Aparecida Bianchi Galati   +7 more
doaj   +1 more source

Transcription of toll-like receptors 2, 3, 4 and 9, FoxP3 and Th17 cytokines in a susceptible experimental model of canine Leishmania infantum infection [PDF]

, 2015
Canine leishmaniosis (CanL) due to Leishmania infantum is a chronic zoonotic systemic disease resulting from complex interactions between protozoa and the canine immune system.
A Ives, A Rodriguez, A Rodriguez-Cortes, A Rodriguez-Cortes, A Rodriguez-Cortes, AB Reis, AK House, AK Rai, Alhelí Rodríguez-Cortés, AM Elassad, BL Travi, C Gallego, C Gonzalez-Lombana, C Maia, C Maia, C Riera, CE O'Neil, CF Alves, CR Engwerda, D Menezes-Souza, D Sacks, D Strauss-Ayali, DA Vargas-Inchaustegui, Damer P. Blake, E Bourreau, F Chappuis, FF Tuon, FF Tuon, G Baneth, GA Cezario, GD Melo, GK Katara, GM Santos-Gomes, H Kumar, IR Peters, J Alvar, J Liese, J Moreno, J Sano, JF Flandin, JM Ehrchen, Jordi Alberola, K Ghosh, K Wolk, Karin Allenspach, KL Silva, L Solano-Gallego, L Solano-Gallego, Laia Solano-Gallego, LM Melo, LP Carvalho, MA Almeida, MG Pitta, MJ de Veer, MJ Rica-Capela, MM Figueiredo, MM Figueiredo, MS Nascimento, N Peters, O Courtenay, O Francino, OA Garden, OR Rodrigues, P Desjeux, P Holzmuller, P Kropf, R Kumar, S Lopez Kostka, S Nylen, S Schmitz, S Tiwananthagorn, S Tolouei, SH Wood, Shazia Hosein, T Korn, TM Castilho, VL da Matta, VS Boaventura, VS Raman, Y Belkaid, Yara M. Traub-Csekö, ZK Peng   +81 more
core   +4 more sources

Efficient and Rapid Arylation of NH₂‐Unprotected Bromobisindole Ethanamines via Suzuki‐Miyaura Coupling: Generating New Leads Against Leishmania

Chemistry – A European Journal, EarlyView.
A library of novel bisindole derivatives was synthesized through an optimized rapid Suzuki‐Miyaura coupling reaction, utilizing NH2‐unprotected bromobisindole ethanamines and boronic acids with yields up to 93%. The compounds were screened for their activity against L. infantum promastigotes.
Alessandro Buono, Aurora Diotallevi, Sara Maestrini, Michele Verboni, Paula Kiuru, Luca Galluzzi, Andrea Duranti, Diego Olivieri, Simone Lucarini   +8 more
wiley   +1 more source

Molecular and serological detection of Leishmania spp. in horses from an endemic area for canine visceral leishmaniasis in southeastern Brazil

Pesquisa Veterinária Brasileira
: This study aimed to verify the occurrence of Leishmania spp. and Leishmania (Leishmania) infantum in horses from a visceral leishmaniasis endemic area in Brazil.
Julia C. Benassi, Graziella U. Benvenga, Helena L. Ferreira, Rodrigo M. Soares, Diogo T. Silva, Vanessa F. Pereira, Vera Letticie A. Ruiz, Trícia Maria F. de S. Oliveira   +7 more
doaj   +1 more source

The use of kDNA minicircle subclass relative abundance to differentiate between Leishmania (L.) infantum and Leishmania (L.) amazonensis

Parasites & Vectors, 2017
Background Leishmaniasis is a neglected disease caused by many Leishmania species, belonging to subgenera Leishmania (Leishmania) and Leishmania (Viannia).
Marcello Ceccarelli, Luca Galluzzi, Aurora Diotallevi, Francesca Andreoni, Hailie Fowler, Christine Petersen, Fabrizio Vitale, Mauro Magnani   +7 more
doaj   +1 more source