The recombinant protein rSP03B is a valid antigen for screening dog exposure to Phlebotomus perniciosus across foci of canine leishmaniasis [PDF]
, 2017 The frequency of sandfly-host contacts can be measured by host antibody levels against sandfly salivary proteins. Recombinant salivary proteins are suggested to represent a valid replacement for salivary gland homogenate (SGH); however, it is necessary ...
Alten +23 more
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Proteome Profiling of Leishmania Infantum Promastigotes
Journal of Eukaryotic Microbiology, 2011 ABSTRACT. A proteome analysis of the promastigote stage of the trypanosomatid parasite Leishmania infantum (MON‐1 zymodeme) is described here for the first time. Total protein extracts were prepared at early logarithmic and stationary phases of replicate axenic cultures and processed by 2D electrophoresis (pH 3–10).
Alcolea, Pedro J. +2 more
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Rapid Detection of Leishmania infantum Infection in Dogs: Comparative Study Using an Immunochromatographic Dipstick Test, Enzyme-Linked Immunosorbent Assay, and PCR [PDF]
, 2002 Current zoonotic visceral leishmaniasis (ZVL) control programs in Brazil include the culling of Leishmania infantum-infected reservoir dogs, a strategy that has failed to prevent a rise of canine and human ZVL cases over the past decade.
Bruce Alex +8 more
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A Calcium- and GTP-Dependent Transglutaminase in Leishmania infantum
Veterinary Sciences, 2023 While human and animal leishmaniasis affect several millions of people worldwide, L. infantum is the species responsible for visceral leishmaniasis in Europe, Middle East, and America. Antileishmanial drugs present issues associated with drug toxicity and increasing parasite resistance.
Almugadam, Shawgi Hago +7 more
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Paf-Metabolic Enzymes and Paf-like Activity in and Promastigotes
European Journal of Inflammation, 2011 Leishmania spp are obligate intracellular protozoan parasites of the mononuclear phagocyte system that cause a spectrum of diseases known as leishmaniasis.
P. Chatzovoulos +5 more
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Miltefosine induces metacaspase and PARP genes expression in Leishmania infantum
Brazilian Journal of Infectious Diseases, 2011 Objectives: Apoptosis is the process of programmed cell death (PCD) that occurs in both animal and plant cells. Protozoan parasites possess metacaspase and these caspase-related proteases could be involved in the PCD pathways in these organisms ...
Shahram Khademvatan +2 more
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Leishmaniasis: new approaches to disease control. [PDF]
, 2003 The leishmaniases afflict the world's poorest populations. Among the two million new cases each year in the 88 countries where the disease is endemic (fig 1), it is estimated that 80% earn less than $2 a day.
Croft, Simon L +3 more
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Revista da Sociedade Brasileira de Medicina Tropical, 2010 INTRODUÇÃO: Leishmaniose visceral é uma zoonose que acomete diversos mamíferos tendo os canídeos domésticos como principais reservatórios em ambiente urbano.
Nely Pinheiro Souza +6 more
doaj +1 more source
Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani [PDF]
, 2020 A chemically diverse range of novel tetraoxanes was synthesized and evaluated in vitro against intramacrophage amastigote forms of Leishmania donovani. All 15 tested tetraoxanes displayed activity, with IC50 values ranging from 2 to 45 µm.
Amado, Patrícia +5 more
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A nationwide survey of Leishmania infantum infection in cats and associated risk factors in Italy
PLoS Neglected Tropical Diseases, 2019 Though scantly investigated, Leishmania infantum infection and clinical cases of leishmaniasis in cats have been recently reported in several countries of the Mediterranean basin, with large variability in prevalence data.
R. Iatta +12 more
semanticscholar +1 more source